Benzohydroxamic acid

HCID 178724751

基本情報

CAS
122231-61-2
標準SMILES
O/N=C(\O)c1ccccc1
InChIKey
VDEUYMSGMPQMIK-UHFFFAOYSA-N
分子式
C7H7NO2
平均分子量
137.14 g/mol

概要

Rhombic crystals or light beige solid. (NTP, 1992)

名称と識別子

優先名称
Benzohydroxamic acid
IUPAC
N-hydroxybenzamide
英語名
Benzenecarboximidic acid, N-hydroxy-, (Z)- (9CI)
分子式
C7H7NO2
分子量
137.13598

名称と別名

N-HydroxybenzamideBENZOHYDROXAMIC ACID495-18-1Benzhydroxamic acidBenzamide, N-hydroxy-Phenylhydroxamic acidBenzoylhydroxamic acidHydroxylamine, N-benzoyl-DTXSID7025421K8YW73872DNSC-147248DTXCID305421
名称をさらに表示
Benzenecarboximidic acid, N-hydroxy-, (Z)- (9CI)
RefChem:163535207-797-6N-Hydroxy-benzamideBenzohydroxamateBenzohyroxamatebenzenecarbohydroxamic acid122231-61-2MFCD00002109

データベース識別子

CAS
122231-61-2
ChEMBL
CHEMBL16300
UNII
K8YW73872D
EC Number
207-797-6
Nikkaji
J1.560A

物性

構造計算による物性

XLogP
0.3
極性表面積
49.3 Ų
水素結合供与体数
2
水素結合受容体数
2
回転可能結合数
1
重原子数
10

実験および物理化学的性質

DrugsPharmaceuticals -> Listed in ZINC15
SpringerMaterials PropertiesChemical shift
LogP0.26
Solubility5 to 10 mg/mL at 74.7 °F (NTP, 1992)
Boiling PointExplodes (NTP, 1992)
Melting Point259 to 266 °F (NTP, 1992)

安全と法規制

GHS分類

GHS Classification · 4 件

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P203, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 33 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Regulatory Information · 3 件

Chemical: Benzamide, N-hydroxy-

Status: No longer Valid Update: 18-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/24948

Benzamide, N-hydroxy-: Does not have an individual approval but may be used under an appropriate group standard

Fire HazardsFlash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Health HazardsACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes of nitrogen oxides. (NTP, 1992)
Reactive GroupAlcohols and Polyols
Reactivity Profile · 1 件

N-HYDROXYBENZAMIDE is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Air and Water ReactionsSlightly soluble in water.

安全と保護具

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1 件

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 件

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE) · 1 件

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

化学と産業

用途と製造

General Manufacturing InformationBenzamide, N-hydroxy-: ACTIVE

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