2-Aminothiazole

HCID 178786969

ノート反応

部分構造検索類似構造を探す

基本情報

CAS: 361381-86-4
標準SMILES: Nc1nccs1
InChIKey: RAIPHJJURHTUIC-UHFFFAOYSA-N
分子式: C3H4N2S
平均分子量: 100.14 g/mol

概要

2-aminothiazole appears as light brown crystals or brown granular solid. (NTP, 1992)

名称と識別子

優先名称: 2-Aminothiazole
IUPAC: 1,3-thiazol-2-amine
英語名: 2-Aminothiazole
分子式: C3H4N2S
分子量: 100.14226

名称と別名

2-AMINOTHIAZOLEaminothiazole96-50-42-ThiazolamineAbadole2-ThiazolylamineAbadolBasedol2-Thiazylamine4-Thiazolin-2-onimineAminothiazolAminotiazol

名称をさらに表示

Thiazole, 2-amino-AminothiazolumUSAF EK-P-5501RP 2921AminotiazoloDTXSID5024508NSC-19005K8WKN668K

データベース識別子

CAS: 361381-86-4
ChEMBL: CHEMBL344760
ChEBI: CHEBI:40782
UNII: 5K8WKN668K
EC Number: 202-511-6
Nikkaji: J3.972A

物性

構造計算による物性

XLogP: 0.4
極性表面積: 67.2 Å²
水素結合供与体数: 1
水素結合受容体数: 3
回転可能結合数: 0
重原子数: 6
形式電荷: 0
複雑度: 48.1

実験および物理化学的性質

SpringerMaterials PropertiesChemical shift

LogP0.38

Solubilityless than 1 mg/mL at 68 °F (NTP, 1992)

Boiling PointDecomposes (NTP, 1992)

Melting Point194 °F (NTP, 1992)

Physical Description2-aminothiazole appears as light brown crystals or brown granular solid. (NTP, 1992)

安全と法規制

GHS分類

GHS Classification · 4 件

Warning

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P304+P340, P305+P351+P338, P319, P330, P337+P317, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 87 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Regulatory Information · 3 件

Chemical: 2-Thiazolamine

Status: Active Update: 11-12-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/21653

2-Aminothiazole: Does not have an individual approval but may be used under an appropriate group standard

Fire HazardsFlash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)

Health HazardsSYMPTOMS: Symptoms of exposure to this compound may include nausea, headache and weakness. It may also cause irritation.

Reactive GroupAmines, Phosphines, and Pyridines

Reactivity Profile2-AMINOTHIAZOLE reacts violently when nitrated with nitric or nitric-sulfuric acids. It is also incompatible with strong oxidizing agents, strong acids, acid chlorides and acid anhydrides. (NTP, 1992)

Air and Water ReactionsInsoluble in water.

安全と保護具

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

First Aid · 1 件

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 件

SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE) · 1 件

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)