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HCID 18321作成日：2026年10月29日

2,3-エポキシ-1,1,1-トリクロロプロパン

2-(トリクロロメチル)オキシラン · 1,2-エポキシ-3,3,3-トリクロロプロパン · 2-トリクロロメチルオキシラン · 1,1,1-トリクロロ-2,3-エポキシプロパン · 3,3,3-トリクロロ1,2-エポキシプロパン · 2,3-エポキシ-1,1,1-トリクロロプロパン · (トリクロロメチル)オキシラン · TRICHLOROPROPANEOXIDE

https://huagongshe.com/ja/chemical/18321

識別子と物理属性

CAS No.	3083-23-6
分子式	C3H3Cl3O
平均分子量	161.41 g/mol
単同位体質量	159.924948 g/mol
SMILES	ClC(Cl)(Cl)C1CO1
InChIKey	VFEXYZINKMLLAK-UHFFFAOYSA-N
PubChem CID	18321
EC No.	221-384-8
DTXSID	DTXSID3025251
現地名	2,3-エポキシ-1,1,1-トリクロロプロパン

化学・物理的性質

XLogP	1.8
極性表面積	12.5
水素結合供与体数	0
水素結合受容体数	1
回転可能結合数	0
重原子数	7
形式電荷	0
複雑度	76
密度	1.495 at 68 °F (NTP, 1992) - Denser than waterwill sink1.4950
溶解度	less than 0.1 mg/mL at 65.3 °F (NTP, 1992)
引火点	152 °F (NTP, 1992)
沸点	300 °F at 764 mmHg (NTP, 1992)226.05°C (rough estimate)
蒸気圧	11.6 mmHg at 77 °F28.5 mmHg at 108 °F65.5 mmHg at 149 °F (NTP, 1992)11.6 [mmHg]
Physical Description	1,2-epoxy-3,3,3-trichloropropane is a clear colorless liquid. (NTP, 1992)Clear colorless liquid[CAMEO]
Kovats Retention Index	885
屈折率	1.4737 (estimate)
安定性	安定。可燃性。強力な酸化剤とは相容れない。
CAS データベース	3083-23-6
EPAの化学物質情報	1,1,1-Trichloro-2,3-epoxypropane (3083-23-6)

化学的特性

colourless liquid

安全性と法規制

GHS 分類	WarningH226 (100%): Flammable liquid and vapor [Warning Flammable liquids]H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]H351 (100%): Suspected of causing cancer [Warning Carcinogenicity]H373 (100%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]P203, P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P317, P318, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
火災危険	This chemical is combustible. (NTP, 1992)
健康有害性	ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes. (NTP, 1992)
有害性の概要	Intraperitoneal LD50 (rat) = 142 mg/kg[RTECS] Enhances the tumor initiating ability of some carcinogens[ChemIDplus] Highly flammable and polymerizable[CAMEO] See Epibromohydrin and Epichlorohydrin.
反応性グループ	Halogenated Organic CompoundsEpoxidesPolymerizable Compounds
Reactivity Alerts	Polymerizable
Reactivity Profile	Epoxides are highly reactive. They polymerize in the presence of catalysts or when heated. These polymerization reactions can be violent. Compounds in this group react with acids, bases, and oxidizing and reducing agents. They react, possibly violently with water in the presence of acid and other catalysts.
Air and Water Reactions	Insoluble in water.
Hazard Classes and Categories	Flam. Liq. 3 (100%)Acute Tox. 4 (100%)Skin Irrit. 2 (100%)Eye Irrit. 2 (100%)STOT SE 3 (100%)Carc. 2 (100%)STOT RE 2 (100%)
消火	Fires involving this compound should be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
応急処置	EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.INHALATION: IMMEDIATELY leave the contaminated areatake deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be usedif not available, use a level of protection greater than or equal to that advised under Protective Clothing.INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
非火災時の漏出対応	SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.STORAGE PRECAUTIONS: You should store this material in a refrigerator. STORE AWAY FROM SOURCES OF IGNITION. (NTP, 1992)
Personal Protective Equipment (PPE)	RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)
毒性	mmo-sat 740 mg/plate APSXAS 17,189,80

用途

使用

Trichloropropene Oxide is a epoxide hydratase inhibitor and possess potential carcinogenic properties.

一般的な説明

Clear colorless liquid.

2,3-エポキシ-1,1,1-トリクロロプロパン

CAS No.

3083-23-6

分子式

C3H3Cl3O

平均分子量

161.41 g/mol

単同位体質量

159.924948 g/mol

SMILES

ClC(Cl)(Cl)C1CO1

InChIKey

VFEXYZINKMLLAK-UHFFFAOYSA-N

PubChem CID

18321

EC No.

221-384-8

DTXSID

DTXSID3025251

現地名

2,3-エポキシ-1,1,1-トリクロロプロパン

化学・物理的性質

XLogP

1.8

極性表面積

12.5

水素結合供与体数

水素結合受容体数

回転可能結合数

重原子数

形式電荷

複雑度

密度

1.495 at 68 °F (NTP, 1992) - Denser than waterwill sink1.4950

溶解度

less than 0.1 mg/mL at 65.3 °F (NTP, 1992)

引火点

152 °F (NTP, 1992)

沸点

300 °F at 764 mmHg (NTP, 1992)226.05°C (rough estimate)

蒸気圧

11.6 mmHg at 77 °F28.5 mmHg at 108 °F65.5 mmHg at 149 °F (NTP, 1992)11.6 [mmHg]

Physical Description

1,2-epoxy-3,3,3-trichloropropane is a clear colorless liquid. (NTP, 1992)Clear colorless liquid[CAMEO]

Kovats Retention Index

885

屈折率

1.4737 (estimate)

安定性

安定。可燃性。強力な酸化剤とは相容れない。

CAS データベース

3083-23-6

EPAの化学物質情報

1,1,1-Trichloro-2,3-epoxypropane (3083-23-6)

化学的特性

colourless liquid

安全性と法規制

GHS 分類

WarningH226 (100%): Flammable liquid and vapor [Warning Flammable liquids]H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]H351 (100%): Suspected of causing cancer [Warning Carcinogenicity]H373 (100%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]P203, P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P317, P318, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

火災危険

This chemical is combustible. (NTP, 1992)

健康有害性

ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes. (NTP, 1992)

有害性の概要

Intraperitoneal LD50 (rat) = 142 mg/kg[RTECS] Enhances the tumor initiating ability of some carcinogens[ChemIDplus] Highly flammable and polymerizable[CAMEO] See Epibromohydrin and Epichlorohydrin.

反応性グループ

Halogenated Organic CompoundsEpoxidesPolymerizable Compounds

Reactivity Alerts

Polymerizable

Reactivity Profile

Epoxides are highly reactive. They polymerize in the presence of catalysts or when heated. These polymerization reactions can be violent. Compounds in this group react with acids, bases, and oxidizing and reducing agents. They react, possibly violently with water in the presence of acid and other catalysts.

Air and Water Reactions

Insoluble in water.

Hazard Classes and Categories

Flam. Liq. 3 (100%)Acute Tox. 4 (100%)Skin Irrit. 2 (100%)Eye Irrit. 2 (100%)STOT SE 3 (100%)Carc. 2 (100%)STOT RE 2 (100%)

消火

Fires involving this compound should be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

応急処置

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.INHALATION: IMMEDIATELY leave the contaminated areatake deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be usedif not available, use a level of protection greater than or equal to that advised under Protective Clothing.INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

非火災時の漏出対応

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.STORAGE PRECAUTIONS: You should store this material in a refrigerator. STORE AWAY FROM SOURCES OF IGNITION. (NTP, 1992)

Personal Protective Equipment (PPE)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

毒性

mmo-sat 740 mg/plate APSXAS 17,189,80