基本情報
- CAS
116817-14-2- 標準SMILES
CNCCC(Oc1cccc2ccccc12)c1cccs1.O=C(O)C(=O)O- InChIKey
NMLRFGBDXFMJJM-UHFFFAOYSA-N- 分子式
- C20H21NO5S
- 平均分子量
- 387.5 g/mol
- 単同位体質量
- 387.11404394
名称と識別子
- 優先名称
- LY 227942
- IUPAC
- N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine;oxalic acid
- 英語名
- (±)-Duloxetine-d5 Oxalate (N-methyl-dj propanamine-d2)
- 分子式
- C20H21NO5S
- 分子量
- 387.45
名称と別名
LY 227942RefChem:925023116817-14-22-Thiophenepropanamine, N-methyl-gamma-(1-naphthalenyloxy)-, ethanedioate (1:1)(S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine oxalate116817-77-7N-Methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine;oxalic acidSCHEMBL3335orb1696281methyl[(3S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl]amine; oxalic acidDTXSID601365346AKOS040752772
名称をさらに表示
rac-Duloxetine Oxalate(±)-Duloxetine-d5 Oxalate (N-methyl-dj propanamine-d2)
T32995N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine oxalate
データベース識別子
- CAS
116817-14-2- PubChem CID
- 19830079
- DTXSID
DTXSID601365346
物性
構造計算による物性
- 極性表面積
- 124 Ų
- 水素結合供与体数
- 3
- 水素結合受容体数
- 7
- 回転可能結合数
- 7
- 重原子数
- 27
- 形式電荷
- 0
- 複雑度
- 383
化学と産業
薬理情報
MeSH Pharmacological Classification
Compounds capable of relieving pain without the loss of CONSCIOUSNESS.
Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.
Drugs that selectively block or suppress the plasma membrane transport of SEROTONIN and NORADRENALINE into axon terminals and are used as ANTIDEPRESSIVE AGENTS.
Any drugs that are used for their effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons.
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