ベルテロイン

説明Berteroin is a sulforaphane analog found in cruciferous vegetables including Chinese cabbage, rucola salad leaves, and mustard oil. At 1.7 μM, it has been shown to double the phase II enzyme quinone reductase activity in mouse hepatoma cells. Berteroin exerts anti-inflammatory activity in LPS-stimulated RAW 264.7 macrophages, inhibiting degradation of IκBα, as well as NF-κB p65 translocation to the nucleus and DNA binding activity. It also suppresses IRAK degradation and phosphorylation of TAK1, p38 MAPK, ERK1/2, and Akt.

天然物の起源Reported found in radish and horseradish.