基本情報
- CAS
29621-88-3- 標準SMILES
N[C@@H](C[Se][Se]C[C@H](N)C(=O)O)C(=O)O- InChIKey
JULROCUWKLNBSN-IMJSIDKUSA-N- 分子式
- C6H12N2O4Se2
- 平均分子量
- 334.11 g/mol
- 単同位体質量
- 335.91274946
概要
RN given refers to parent cpd; structure
名称と識別子
- 優先名称
- Selenocystine
- IUPAC
- (2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]diselanyl]propanoic acid
- 現地名
- L-セレノシスチン一水和物
- 英語名
- L-SELENOCYSTINE
- 分子式
- C6H12N2O4Se2
- 分子量
- 334.09
名称と別名
1464-43-3CHEBI:28553RefChem:8848323,3'-diselane-1,2-diylbis(2-aminopropanoic acid)3,3'-Diselenobisalanine3,3'-DiselenodialanineSelenocystineL-Selenocystine29621-88-3Seleno-L-cystineSelenocystine, L-C6H12N2O4Se2
名称をさらに表示
L-セレノシスチン一水和物(R,R)-3,3'-ジセレノビス(2-アミノプロピオン酸)一水和物セレノ-L-シスチン一水和物L‐セレノシスチンセレノ-L-シスチンH-Se-Cystine-OHL-SELENOCYSTINE 98%L-Selenocystine,98%Seleno-L-cystine 95%3’-diselenodi-l-alanin3,3'-DISELENO-L-ALANINEl-3,3’-diselenodialanine
L-3,3'-DiselenodialanineAlanine, 3,3'-diselenodi-, L-(2R,2'R)-3,3'-diselanediylbis(2-aminopropanoic acid)MFCD00800971261B157KR83,3'-Diselenobis[L-alanine]L-Selenocystine Preparation Kit(2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]diselanyl]propanoic acid
データベース識別子
- CAS
29621-88-3
物性
構造計算による物性
- 極性表面積
- 127 Ų
- 水素結合供与体数
- 4
- 水素結合受容体数
- 6
- 回転可能結合数
- 7
- 重原子数
- 14
- 形式電荷
- 0
- 複雑度
- 192
物理化学的性質
- 融点
- 224.5 · 224.5-229.5 °C (lit.)
- 沸点
- 538.3 · 538.3±60.0 °C(Predicted)
- 貯蔵温度
- 2 · 2-8°C
- 溶解性
- Aqueous Acid (Slightly), Aqueous Base (Slightly)
- 酸解離定数(Pka)
- 1.69 · 1.69±0.10(Predicted)
- 外見
- 粉
- 色
- 黄色
- BRN
- 1969559 · 1969559
- 安定性
- Hygroscopic
- 主な用途
- ペプチド合成
- InChI
- 1S/C6H12N2O4Se2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1
- InChIKey
- JULROCUWKLNBSN-IMJSIDKUSA-N
- SMILES
- N[C@@H](C[Se][Se]C[C@H](N)C(O)=O)C(O)=O
化学的性質
化学的特性yellow fine powder
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
Danger
H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
P260, P261, P264, P270, P271, P273, P301+P316, P304+P340, P316, P319, P321, P330, P391, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 41 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
危険有害性情報
Hazard Classes and CategoriesAcute Tox. 3 (100%)
安全データ
- wgk
- 3
- rtecs
- AY6032000
- ridadr
- UN 3283 6.1/PG 3
- PRTR法
- 第一種指定化学物質
- hs_code
- 29319090
- risk_code
- 23/25-33-50/53
- 安衛法
- 57,57-2
- hazard_code
- T,N
- safety_code
- 20/21-28-45-60-61
- hazard_class
- 6.1
- packing_group
- III
- 毒劇物取締法
- 毒物
- Hazard Classifications
- Acute Tox. 3 InhalationAcute Tox. 3 OralAquatic Acute 1Aquatic Chronic 1STOT RE 2
- ストレージクラス
- 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
化学と産業
薬理情報
MeSH Pharmacological Classification
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
応用分野
説明L-Selenocystine is a diselenide-bridged amino acid that may be confused with selenocysteine (Sec), which is a rare amino acid featuring a single selenium atom. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions. This compound can be reduced by low molecular thiols and disulfide reductases to Sec. It is reduced to Sec by mammalian thioredoxin reductase (apparent Km = 6.0 μM), and this property can be used to assay thioredoxin reductase activity. L-Selenocystine induces an unfolded protein response, ER stress, and large cytoplasmic vacuolization in HeLa cells and has cytostatic effects in a range of cancer cell types.
使用Seleno-L-cystine can be used for the synthesis of:Biologically active selenol compounds.Non-natural selenylated diamino acids.
サプライヤー100 社
国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖南韵邦生物科技股份有限公司0731-88532326 13319508186 · [email protected]
関連反応
0 件
現在のフィルター条件では反応記録がありません。
化合物ノート
読み込み中…