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テトラペプチド-61

Epitalon

HCID 219042
ノート反応
基本情報概要名称と識別子物性化学と産業関連反応化合物ノート
部分構造検索類似構造を探す

基本情報

CAS
307297-39-8
標準SMILES
C[C@H](N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)O
InChIKey
HGHOBRRUMWJWCU-FXQIFTODSA-N
分子式
C14H22N4O9
平均分子量
390.35 g/mol
単同位体質量
390.13867829

概要

Epitalon is an organic molecular entity.

名称と識別子

優先名称
Epitalon
IUPAC
(4S)-4-[[(2S)-2-aminopropanoyl]amino]-5-[[(2S)-3-carboxy-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
現地名
テトラペプチド-61
英語名
Epitalon
分子式
C14H22N4O9
分子量
390.35

名称と別名

Epitalon307297-39-8EpithalonEpithaloneAla-Glu-Asp-GlyAE-0 peptideO65P17785GGlycine, L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-alanyl-glutamyl-aspartyl-glycineDTXSID80952957RefChem:921052DTXCID801381023
名称をさらに表示
テトラペプチド-61EpithalonAcetateGlycine, L-alanyl-L-a-glutamyl-L-a-aspartyl-ALAGLUASPGLYAla-Glu-Asp-Gly-OHEptaton EpithalonEpithalon(Epitalon) acetateEpitalon, Epithalon TetraPeptideEpithalon, Epithalon Tetra Peptide
(S)-4-((S)-2-aminopropanamido)-5-(((S)-3-carboxy-1-((carboxymethyl)amino)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid(4S)-4-[[(2S)-2-aminopropanoyl]amino]-5-[[(2S)-3-carboxy-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid64082-79-7EpithalaminL-Alanyl-L-glutamyl-L-aspartyl-glycineEpithalamineEpithalon?UNII-O65P17785G

データベース識別子

CAS
307297-39-8、64082-79-7

物性

構造計算による物性

XLogP
-5.5
極性表面積
225 Ų
水素結合供与体数
7
水素結合受容体数
10
回転可能結合数
12
重原子数
27
形式電荷
0
複雑度
607

物理化学的性質

沸点
959.8 · 959.8±65.0 °C(Predicted)
比重(密度)
1.466 · 1.466±0.06 g/cm3(Predicted)
貯蔵温度
-20 °C · Store at -20°C
溶解性
250 mg/mL · DMSO: 250 mg/mL (495.67 mM)
酸解離定数(Pka)
3.16 · 3.16±0.10(Predicted)
外見
Solid
色
White to off-white
化粧品成分の機能
口腔ケアスキンコンディショニング - その他抗酸化物質肌を保護するヘアコンディショニング
InChIKey
HGHOBRRUMWJWCU-VTCOHLDGNA-N
SMILES
[C@H](CC(=O)O)(C(=O)NCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)C |&1:0,15,24,r|

化学と産業

応用分野 · 2 件

説明Epitalon (also known as Epithalon or Epithalone) is the synthetic version of the polypeptide Epithalamin which is naturally produced in the pineal gland. It was synthesized by Vladimir Khavinson, a Russian professor and gerontologist, whose research focused on the development of peptide preparations used to restore function in various organs in order to prevent and reverse the aging process. He is currently the Director of the Saint Petersburg Institute of Bioregulation and Gerontology.Epitalon is considered the "fountain of youth" peptide. It is a tetra-peptide, which means that it is composed of four amino acid chains. The peptide is used to regulate the cell cycle during telomerase activity. Telomerase, also called telomere terminal transferase, is an enzyme made of protein and RNA subunits that elongates chromosomes. When telomerase activity is not present (when we age), our cells age. Our telomeres get shorter and begin to die off. If telomerase is activated in our cells, our telomeres lengthen, the cell continues to grow and divide, delaying the aging process. (UT Southwestern Medical Lab)https://www.amisantabarbara.com/epitalon

来歴Epitalon was discovered and developed by the Russian scientist and gerontologist Professor, Doctor of Medical sciences Vladimir Khavinson of St. Petersburg Institute of Bioregulation and Gerontology, whose research is focused on the development of peptide preparations used to restore function in various organs in order to prevent and reverse the aging process. Epitalon was identified as active component of a bovine pineal gland extract (known as Epithalamin).Low-molecular peptides isolated from pineal gland and Epithalamin of animals were studied in different biologic models. Most all performed scientific studies and clinical trials of Epitalon and Epithalamin have been conducted just by already mentioned St. Petersburg Institute of Bioregulation and Gerontology in Russia, primarily overseen by Professor Vladimir Khavinson, who has been involved in this research already for over 35 years, and has merit not only in the discovery of epitalon, but also in its highly advanced scientific and clinical review. Throughout this time, Epitalon has been extensively investigated in animal and human clinical trials and today is one of the best scientifically investigated peptides.https://beringomega.org

サプライヤー2 社

杭州摩库生物医药科技有限公司

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化合物ノート

読み込み中…

このページの内容基本情報概要名称と識別子物性化学と産業関連反応化合物ノート
PubChem CID
219042
DTXSID
DTXSID80952957
ChEBI
CHEBI:230091
UNII
O65P17785G
+86-057181025280; +8617767106207 · [email protected]
南京克罗托鲁宁医药科技有限公司13382066392

補足説明

定義本品は、アラニン、アスパラギン酸、グルタミン酸及びグリシンからなる合成テトラペプチドである。