Sodium hydrogen difluoride

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

Call a doctor.

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

General First Aid:

· Wear positive pressure self-contained breathing apparatus (SCBA).

Biological Exposure Indices (BEI) [ACGIH] - Fluorides in urine = 2 mg/L prior to shift or 3 mg/L at end of shift; (Repeated measurements recommended.)

1.0 [mg/m3], inhalable fraction, as F[German Research Foundation (DFG)]

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

Immediate precautionary measure

2.5 [mg/m3], as F

8 hr Time Weighted Avg (TWA): 2.5 mg/cu m. /Fluorides, as F/

Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded. /Fluorides, as F/

A4; Not classifiable as a human carcinogen. /Fluorides, as F/

Biological Exposure Index (BEI): Determinant: fluorides in urine; Sampling Time: prior to shift; BEI: 3 mg/g creatinine. Determinant: fluorides in urine; Sampling Time: end of shift; BEI: 10 mg/g creatinine. The determinant may be present in biological specimens collected from subjects who have not been occupationally exposed, at a concentration which could affect interpretation of the result. Such background concentrations are incorporated in the BEI value. The determinant is nonspecific, since it is also observed after exposure to other chemicals. /Fluorides/

1.2 [mg/m3]

13 [mg/m3]

79 [mg/m3]

Rubber gloves, safety glasses, self-contained breathing apparatus. (USCG, 1999)

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

Burns of the eye by hydrofluoric acid can be devastating. Anhydrous hydrogen fluoride has been known to destroy the eye and to require enucleation ... . The danger of hydrofluoric acid solutions depends upon the concentration. /Anhydrous hydrogen fluoride/

Industrial experience in chemical manufacturing where a mixture of fluorine, fluorides, and hydrogen fluoride may be present in the air indicates that conjunctival hyperemia in the palpebral tissue occurs commonly, irritation of the eyelids occurs occasionally, but corneal disturbance is rare. /Hydrogen fluoride/

Less than 1 g by mouth, however, has caused dangerous poisoning; whereas 120 g has been survived, probably because of prompt vomiting. Six grams have been administered intravenously to a teenager without signs of systemic toxicity, but the dosage was given intermittently over a period of 9 days. The systemic toxicity of sodium fluosilicate is about equal to that of sodium fluoride, whereas the less soluble cyrolite is much less toxic. /Sodium fluoride/

A remarkable mass of poisoning, involving 263 victims of whom 47 died, occurred at the Oregon State Hospital when sodium fluoride roach powder mistaken for powdered milk was added scrambled eggs. The prepared dish was rejected by some because of a salty or soapy taste and produced numbness of the mouth in others. Toxic signs and symptoms consisted of abrupt and severe nausea, vomiting and diarrhea, followed promptly by abdominal burning and cramps. In many cases blood was noted in the vomitus and feces. General collapse was evidenced by pallor, weakness, shallow pulse and respirations, weak heart sounds, wet cold skin, cyanosis, mydriasis and coma. Some victims also experienced a thick, mucoid discharge from the mouth and nose, paralysis of the muscles of deglutution, painful carpopedalspasms of the extremities and localized or generalized urticaria. /Sodium fluoride/

For more Human Toxicity Excerpts (Complete) data for SODIUM HYDROGEN DIFLUORIDE (6 total), please visit the HSDB record page.

OCCURS ARTIFICIALLY FROM TIN PLATE PRODUCTION; NEUTRALIZER IN LAUNDRY RINSING OPERATIONS; PRESERVATIVE FOR ZOOLOGICAL & ANATOMICAL SPECIMENS; ETCHING GLASS; ANTISEPTIC.

LEATHER BLEACH

CLEANER FOR STONE & BRICK BUILDING FACES.

The clastogenic potential of sodium fluoride was determined both in vitro (using cultured human lymphocytes) and in vivo (using the rat bone-marrow micronucleus test). The incidence of chromosome aberrations in human lymphocyte cultures exposed to 20 or 40 ug/ml sodium fluoride (3 and 9% respectively) was significantly increased compared it control cultures (0.5%). However, the incidence of micronucleated polychromatic erythrocytes in male AP rats dosed 1000 mg/kg sodium fluoride (the maximum tolerated dose over 24 hr) or 500 mg/kg sodium fluoride was similar to that in the animals dosed distilled water (vehicle control). Thus, sodium fluoride is clastogenic in vitro but not in vivo.

... Extensive experimental evaluation of possible treatments of hydrofluoric acids burns of rabbit eyes, which, to the extent that rabbit and human eyes are comparable, appears to provide a sound scientific basis for a choice. Fluoride ion is toxic when it gains access to the corneal stroma through damage of the corneal epithelium by low acid pH. ... Compared the results of irrigating burned eyes for 30 minutes with one liter each of a series of substances designed to inactivate fluoride ion, and separately evaluated the toxicity of these substances themselves. ... Subconjunctival injections ... concluded that subconjunctival 10% calcium gluconate or irrigation with 0.2% benzethionum chloride or 0.05% benzalkonium chloride were themselves too injurious to normal rabbit eyes to recommend for clinical use. ... Found the only non-toxic treatment with therapeutic value was a single irrigation with isotonic sodium chloride or magnesium chloride. ... Found that repeated irrigation was inadvisable because it strikingly increased the frequency of corneal ulceration in burned eyes. ... The simplest and most effective first-aid treatment was copious irrigation with water or saline. /Hydrofluoric acid/

Bottled water packaged in the USA to which no fluoride is added shall not contain fluoride in excess of 1.8 mg/l at 63.9-70.6 °F. Bottled water packaged in the USA to which fluoride is added shall not contain fluoride in excess of 1.2 mg/l at 63.9-70.6 °F. Imported bottled water to which no fluoride is added and imported bottled water to which fluoride is added shall not contain fluoride in excess of 1.4 mg/l and 0.8 mg/l, respectively. /Fluoride/

Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 100 lb or 45.4 kg. The toll free number of the NRC is (800) 424-8802; In the Washington D.C. metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).