(±)-イソボルネオール

解説(±)-イソボルネオール，ショウノウや香料合成の中間体。 DL体は融点 212℃の結晶。植物精油には見出されないモノテルペンアルコールである。

説明Isoborneol has a piney, camphoraceous odor. May be prepared by the hydrolysis of isobomyl acetate, or by catalytic reduction of camphor (both d- and ι-isomers); the optically inactive compound can be prepared by treating camphene with a 1:1 mixture of sulfuric acid and glacial acetic acid and then hydrolyzing the isobomyl acetat.

天然物の起源Reported found in the oil of Abies sibirica and a few other essences and in the essential oil from roots of Chamaeciparis formosensis. Also reported found in apple, papaya, blackberry, cinnamomum, ginger, thymus, cheeses, cognac, Ocimum basilicum, rosemary, temoe lawak (Curcuma xanthorriza Roxb.) turmeric, sage, clary sage, ashanti pepper, German chamomile oil, eucalyptus oil and mastic gum leaf oil

使用Isoborneol is a monoterpene and a component of several plant essential oils, showed dual viricidal activity against herpes simplex virus 1 (HSV-1).

一般的な説明Isoborneol is a monoterpene and a known antioxidant, which is a component of several plant essential oils.

製造方法By the hydrolysis of isobornyl acetate, or by catalytic reduction of camphor (both d- and l-isomers); the optically inactive compound can by prepared by treating camphene with a 1:1 mixture of sulfuric acid and glacial acetic acid and then hydrolyzing the isobornyl acetate

純化方法Crystallise isoborneol from EtOH or pet ether (b 60-80o). It sublimes in a vacuum. The 4-nitrobenzoyl derivative has m 153o. [Yager & Morgan J Am Chem Soc 57 2081 1935, Beilstein 6 II 80, 6 III 299, 6 IV 281.]