2-ドデシルベンゼンスルホン酸ナトリウム

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.；SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.；INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.；INGESTION: If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

Extinguish fire with water.

If material on fire or involved in fire: Extingiush fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.)

Land spill: Dig a pit, pond, lagoon, or holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water.

Water spill: If dissolved, apply activated carbon at ten times the spilled amount in region of 10 ppm or greater concentration. Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates.

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

If material not involved in fire: Keep material out of water sources and sewers. Build dikes to contain flow as necessary.

Personnel protection: Avoid breathing vapors, or dusts. Keep upwind. Wash away any material which may have contacted the body with copious amounts of soap and water.

1.3 [mg/m3]

14 [mg/m3]

87 [mg/m3]

Rubber gloves, safety glasses. (USCG, 1999)

Rubber gloves, safety glasses.

Personnel protection: Wear appropriate chemical boots, protective gloves, and goggles.

TERRESTRIAL FATE: Based on a recommended classification scheme(2), sodium dodecylbenzenesulfonate should have high mobility(SRC) in soil based on an estimated Koc value of 110.5(1,SRC). Biodegradation of sodium dodecylbenzenesulfonic acid is expected to be an important fate process for aerobic conditions based on a variety of biodegradation studies(5-20). Volatilization of sodium dodecylbenzenesulfonic acid is not expected from moist or dry soils based on an estimated vapor pressure of approximately 2.29X10-15 mm Hg at 25 °C(3) and an estimated Henry's Law constant of 6.27X10-8 atm-cu m/mole(4).

AQUATIC FATE: Sodium dodecylbenzenesulfonate is expected to be essentially non-volatile from water(2) based upon an estimated Henry's Law constant of 6.27x10-8 atm cu m/mol(1,SRC). Biodegradation of sodium dodecylbenzenesulfonate is expected to be an important fate process for aerobic conditions based on a variety of biodegradation studies(3-18). Aquatic bioconcentration, adsorption to sediment, and hydrolysis are not expected to be important fate processes in aquatic environments(SRC).

ATMOSPHERIC FATE: Based on an estimated vapor pressure of approximately 2.29x10-15 mm Hg at 25 °C(1), sodium dodecylbenzenesulfonate will exist in the atmosphere in the particulate phase(2). Removal of sodium dodecylbenzenesulfonate from the atmosphere can occur through wet deposition(SRC).

Aquatic: Water temperature affects biodegration. The rate of sodium-C12 linear alkylbenzene sulfonic acids biodegradation in Chesapeake Bay water was max at 25-30 °C and decreased at lower incubation temperatures. /Sodium-C12 linear alkylbenzene sulfonic acids/

Terrestrial: The adsorption of sodium-C12 linear alkylbenzene sulfonic acids is affected by the type of soil. The affinity of the soil for surfactants competes with microbial attack, slowing biodegradation. /Sodium-C12 linear alkylbenzene sulfonic acids/

Salts of alkylbenzene sulfonates, including ammonium dodecylbenzenesulfonate, calcium dodecylbenzenesulfonate, DEA-dodecylbenzenesulfonate, isopropylamine dodecylbenzenesulfonate, magnesium isodecylbenzenesulfonate, MIPA-dodecylbenzenesulfonate, potassium dodecylbenzenesulfonate, sodium decylbenzenesulfonate, SDDBS, sodium tridecylbenzenesulfonate, TEA-DDBS, and TEA-tridecylbenzenesulfonate, are safe as cosmetic ingredients in the practices of use given in this safety assessment when formulated to be nonirritating.

Safe for use in cosmetics, with qualifications

Concentrations of linear alkylbenzenesulfonates in sewage samples from a mechanical-biological sewage treatment plant in Rome ranged from 257-2305 ug/l and 0.8-9.8 ug/l for raw and treated sewage, respectively, depending on the number of carbons on the alkyl chain (C9-C13)(1). The concentration of linear alkylbenzenesulfonates in Swedish municipal waste waters were 6.2 mg/l in raw sewage, from 0.06 to 4.0 mg/l in primary effluents, and from 0.07 to 0.10 mg/l in secondary effluents(2). The concentrations of linear alkylbenzenesulfonates (C10-C14) for three sewage treatment plants in Spain were between 8.4 and 14.0 mg/g (average 12.6) and 12.1 to 18.8 mg/g (average 15.8) for nondigested and digested sludges, respectively(3). /Linear alkylbenzenesulfonates/

Dodecylbenzenesulfonic acid sodium salt will dissociate to the anionic form (based on a pKa of 2.554 for dodecylbenzenesulfonic acid(5)) in the environment and the anionic form is expected to be even more mobile than indicated by the estimated Koc's for the undissociated sulfonic acid(SRC). Using a structure estimation method based on molecular connectivity indices(1), the Koc for dodecylbenzenesulfonic acid can be estimated to be about 1.71X10+4(SRC). However, the Koc for sodium dodecylbenzenesulfonate can be estimated to be about 110.5(SRC) based on an experimental water solubility of 800 mg/l(3) and a regression derived equation(2). Based on an experimental log Kow value of 1.96(6), the Koc for sodium dodecylbenzenesulfonate can also be estimated to be 278(SRC) using a regression derived equation(2). According to a suggested classification scheme(4), these estimated Koc values suggest that dodecylbenzenesulfonate has high soil mobility.

MAY CAUSE SKIN IRRITATION. IF SWALLOWED WILL CAUSE VOMITING.

... /ALKYL BENZENE SULFONATE/ DETERGENT USED INDUSTRIALLY HAS BEEN HELD RESPONSIBLE FOR DELICATE PUNCTATE SPECKLING OF CORNEAL EPITHELIUM IN PALPEBRAL FISSURE IN 92 WORKERS ... EXPOSED TO THE POWDER IN RUMANIA. ... DISTURBANCE WAS STILL PRESENT A YR LATER. /ALKYL BENZENE SULFONATE/

PROLONGED SKIN CONTACT WITH SOLN MAY CAUSE IRRITATION, BUT SENSITIZATION OR ALLERGIC REACTIONS ARE RARE. /ALKYL ARYL SODIUM SULFONATES/

... IN INDUSTRIAL, INSTITUTIONAL AND CHEMICAL DETERGENTS AND CLEANERS SUCH AS HEAVY DUTY LAUNDRY PRODUCTS; CAR, TRUCK, AND BUS CLEANERS; METAL CLEANING PRODUCTS; SPECIALTY CLEANERS AND SANITATION PRODUCTS; EMULSIFIERS, SUSPENSION OR WETTNG AGENTS, ABSORBANTS IN PESTICIDE AND OTHER AGRICULTURAL CHEMICALS; FOAMING AND WETTING AGENT IN PULP AND PAPER PRODUCTS; LATEX, TEXTILE, RUBBER AND POLYMER PROCESSING

Sodium dodecylbenzenesulfonate's production and use as an anionic detergent(1) results in its release to the environment through various waste streams(SRC).

ONLY WHEN MASSIVE AERATION WAS EMPLOYED WAS SODIUM DODECYLBENZENESULFONATE DEGRADED BY SOME UNSPECIFIED SPECIES OF MARINE BACTERIA WHEN PRESENT AS SOLE CARBON SOURCE.

The fate of benzene-labeled linear alkylbenzene sulfonates (LAS) was investigated in 2 kinds of soil under upland conditions in a biometric flask. ... Although there was a marked difference in the amt of unextractable residue between tested soils, the patterns of (14)CO2 evolution were similar, reaching 30, approx 45% of the applied (14)C at 60 days after treatment. Thus, the benzene ring of LAS was degraded in unsaturated soils. No movement of (14)C-LAS-Ca and (14)C-LAS-Na in peanuts was observed even at 30 days after foliar application. /Linear alkylbenzene sulfonates/

EXPT WITH MICROORGANISMS ... SHOWN ... /ALKYLBENZENESULFONATES/ DEGRADED TO ALKYLBENZENE UNDER LIBERATION OF SULFITE, WHICH ... OXIDIZES TO SULFATE. LONGER CHAINS DEGRADE BY C-2 BETA-OXIDATION UNTIL A C-4 RESIDUE REMAINS. CMPD MAY THEN BE HYDROXYLATED TO CATECHOL WITHOUT FURTHER SIDE CHAIN ATTACK. /ALKYLBENZENESULFONATES/

The most common metabolic pathway for surfactant biodegradation is the beta-oxidation sequence which is also used for fatty acid metabolism in all organisms. ... In anionic surfactants, removal of the hydrophilic sulfonate ... by an alkylsulfatase usually precedes beta-oxidation resulting in the production of sulfite and free sulfate groups. The desulfonation usually occurs at the cell membrane to prevent denaturation of intracellular proteins by intact surfactant, although some strains of Pseudomonas can degrade the surfactant totally without prior desulfonation. /SOAP AND DETERGENTS/

For more Environmental Biodegradation (Complete) data for SODIUM DODECYLBENZENESULFONATE (9 total), please visit the HSDB record page.

Concentrations of linear alkylbenzenesulfonates in Rapid Creek sediments in South Dakota in October of 1980 are as follows: 275, 9.1, 8.4, 2.7, 1.4, and 1.5 mg/kg at distances of 0.8, 7, 11.7, 25.3, 48, and 87.2 km downstream from a sewage treatment plant emission source(1). The average concentration of linear alkylbenzenesulfonates from river, estuarine, and Tokyo Bay sediments taken from the Tokyo area were 107, 4.82, and 0.02 ug/g of dry sediment(2,3). The average linear alkylbenzenesulfonate concentration in marine sediments adjacent to a domestic sewage discharge point in Spain was 0.1 ug/g(4). Linear alkylbenzenesulfonate was identified in most of the 37 bottom sediment samples taken from the Mississippi River between New Orleans and Minneapolis at concentrations of less than 0.01 to 5.0 mg/kg(5).

The BCF for sodium dodecylbenzenesulfonate has been experimentally determined to be 64(1) and calculated to be 107(1). The bioconcentration factor for sodium dodecylbenzenesulfonate has also been experimentally determined to be 130 (ug/g fish)/(ug/g water) using Golden Orfe(2). These experimental and estimated BCF values suggest that bioconcentration of sodium dodecylbenzenesulfonate in aquatic organisms will not be an important fate process(SRC).

The Henry's Law constant for the acid of sodium dodecylbenzenesulfonate can be estimated to be 6.27X10-8 atm-cu m/mole using a structure estimation method(1). This value of Henry's Law constant indicates that sodium dodecylbenzenesulfonate is essentially non-volatile from water(2).

MECHANISM OF DEATH AFTER HIGH ORAL DOSES IN ANIMALS IS NOT KNOWN. AT LOW LEVELS FEEDING EXPERIMENTS HAVE PRODUCED NO EVIDENCE OF SYSTEMIC TOXICITY IN RATS. /ALKYL ARYL SODIUM SULFONATES/

SODIUM ALKYLBENZENESULFONATE ADDED TO HAMSTER LUNG CELL CULTURE @ 62.5 UG/ML INDUCED CELL MUTATION, NO EFFECT ON SISTER CHROMATID EXCHANGE. SODIUM ALKYLBENZENESULFONATE ADDED TO HAMSTER LUNG CELL CULTURE MEDIUM @ 125 UG/L DESTROYED THE CELLS COMPLETELY. /SODIUM ALKYLBENZENESULFONATE/

SODIUM DODECYLBENZENE SULFONATE FED TO RATS FOR 90 DAYS. NO ADVERSE EFFECTS IN GROWTH, FOOD CONSUMPTION & UTILIZATION, SURVIVAL, BLOOD OR URINE VALUES, ORGAN WT, BODY WT, OR NO GROSS OR MICROSCOPIC TISSUE CHANGE.

THE SURFACTANT, SODIUM LAURYLBENZENESULFONATE, INHIBITED FERTILIZATION, & RETARDED EMBRYONIC DEVELOPMENT & BONE FORMATION IN ANTHOCIDARIS CRASSISPINA, CLYPEASTER JAPONICUS, HEMICENTROTUS PULCHERRIMUS, AND PSEUDOCENTROTUS DEPRESSUS. 50% INHIBITION WAS OBSERVED WHEN EGGS WERE EXPOSED TO 4-5 UMOL. MORPHOLOGICAL CHANGES WERE OBSERVED.

For more Non-Human Toxicity Excerpts (Complete) data for SODIUM DODECYLBENZENESULFONATE (11 total), please visit the HSDB record page.

Chemical: Benzenesulfonic acid, dodecyl-, sodium salt (1:1)

Benzenesulfonic acid, dodecyl-, sodium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Benzenesulfonic acid, dodecyl-, sodium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Sodium Dodecylbenzene Sulfonate is listed in the dataset of EPA Human Health Benchmarks for Pesticides under the Safe Drinking Water Act (40 eCFR 141)

Status: Active Update: 21-12-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/11639

Sodium lauryl benzene sulphonate: Does not have an individual approval but may be used under an appropriate group standard

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 1,000 lb or 454 kg. The toll free number of the NRC is (800) 424-8802; In the Washington D.C. metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).

CIR ingredient: Sodium Dodecylbenzenesulfonate

Used as anionic detergent; [Merck Index] Used in the textile processing industry and in pesticides; [IUCLID]

Textiles (Fiber & Fabric Manufacturing) [Category: Industry]；Farming (Pesticides) [Category: Industry]

Anionic detergent

USED IN INDUSTRIAL, INSTITUTIONAL AND CHEMICAL DETERGENTS AND CLEANERS SUCH AS HEAVY DUTY LAUNDRY PRODUCTS; CAR, TRUCK, AND BUS CLEANERS; METAL CLEANING PRODUCTS; SPECIALTY CLEANERS AND SANITATION PRODUCTS; EMULSIFIERS, SUSPENSION OR WETTNG AGENTS, ABSORBANTS IN PESTICIDE AND OTHER AGRICULTURAL CHEMICALS; FOAMING AND WETTING AGENT IN PULP AND PAPER PRODUCTS; LATEX, TEXTILE, RUBBER AND POLYMER PROCESSING

Dodocylbenzenesulfonate used in the foam separation of iron (III) hydroxide flox, is recovered from the collapsed foam by treatment with sodium hydroxide, sodium carbonate surfactant recovery; sodium sulfate is less effective. /Dodecylbenzenesulfonate/

(1984) 3.05X10+9 g /ALKYL BENZENE SULFONIC ACID AND SALTS/

(1974) Negligible

(1984) 4.54X10+9 g /ANIONIC SURFACE ACTIVE AGENTS/

(1974) Negligible

2023: 25,000,000 - <40,000,000 lb；2022: 25,000,000 - <40,000,000 lb；2021: 10,000,000 - <25,000,000 lb；2020: 10,000,000 - <25,000,000 lb

(1972) 1.65X10+11 G

(1975) 1.51X10+11 G

(1984) 9.32X10+10 g

(1974) 364.1 Million lbs/year

2.34X10+8 kg (1992)

HEAVY DUTY POWDER DETERGENTS, 50%; HEAVY DUTY LIQUID DETERGENTS, 12%; LIGHT DUTY LIQUID DETERGENTS, 15%; MISCELLANEOUS HOUSEHOLD CLEANER, 5%; INDUSTRIAL, INSTITUTIONAL, COMMERICAL CLEANERS, 13%; INDUSTRIAL PROCESSES AND AGRICULTURAL, 5% (1981)

Cleaning agent；Corrosion inhibitor；Not Known or Reasonably Ascertainable；Emulsifier；Soil amendments (fertilizers)；Intermediate；Foamant；Lubricating agent；Processing aids not otherwise specified；Surfactant (surface active agent)；Dust suppressant

REACTION OF A MIXTURE OF MONOCHLOROPARAFFINS HAVING PREDOMINANTLY TWELVE CARBON CHAIN LENGTHS WITH BENZENE IN THE PRESENCE OF AN ALUMINUM CHLORIDE CATALYST, FOLLOWED BY SULFONATION WITH SULFURIC ACID OR SULFUR TRIOXIDE & REACTION WITH SODIUM HYDROXIDE

BENZENE IS ALKYLATED WITH DODECENE, TO WHICH IT ATTACHES ITSELF IN ANY SECONDARY POSITION. RESULTING DODECYLBENZENE IS SULFONATED WITH SULFURIC ACID ... FOR LINEAR ALKYL SULFONATE (STRAIGHT-CHAIN ALKYL), THE DODECENE MAY BE REMOVED FROM KEROSINE OR CRUDES BY MOLECULAR SIEVE, MAY BE FORMED BY ZIEGLER POLYMERIZATION OF ETHYLENE, OR BY CRACKING WAX PARAFFINS TO ALPHA-OLEFINS.

VET: AS WETTING AGENT OR DETERGENT IN INSECTICIDAL DIPS FOR DOGS (0.2-0.5% IN FINAL DILUTION) & WITH SANITIZERS FOR POULTRY DRINKING WATER (30 MG/GAL), WASHING EGGS (150 MG/GAL), & ON PREMISES & EQUIPMENT (300 MG/GAL).

81% PURE, 13% SODIUM SULFATE

Grades of purity: 40% water; varies with manufacturer and use.

ARYLAN SBC

For more Formulations/Preparations (Complete) data for SODIUM DODECYLBENZENESULFONATE (43 total), please visit the HSDB record page.

EPA Safer Chemical Functional Use Classes -> Surfactants

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Cosmetics -> Emulsifying; Surfactant