リボフラビンリン酸エステルナトリウム

Riboflavin sodium phosphate

HCID 23666409
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基本情報

CAS
130-40-5
標準SMILES
Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(C[C@H](O)[C@H](O)[C@H](O)COP(=O)([O-])O)c2cc1C.[Na+]
InChIKey
OHSHFZJLPYLRIP-BMZHGHOISA-M
分子式
C17H20N4NaO9P
平均分子量
478.3 g/mol
単同位体質量
478.08655951

名称と識別子

優先名称
Riboflavin sodium phosphate
IUPAC
sodium [(2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] hydrogen phosphate
現地名
リボフラビンリン酸エステルナトリウム
英語名
Riboflavin 5'-Monophosphate Sodium Salt
分子式
C17H21N4O9P.Na
分子量
479.33

名称と別名

130-40-5riboflavin sodium phosphateRIBOFLAVIN PHOSPHATE SODIUMRiboflavin-5-phosphate sodiumRiboflavin 5'-monophosphate sodium saltRiboflavina 5 fosfato de sodioRiboflavine-5'-phosphate sodiumRiboflavin 5'-phosphate sodium anhydrousRiboflavin 5'-(dihydrogen phosphate), sodium salt (1:1)Flavin Mononucleotide Sodium SaltSodium Riboflavin PhosphateRIBOFLAVIN 5-PHOSPHATE SODIUM
名称をさらに表示
リボフラビン5'-モノホスファートナトリウムホスフランリボフラビンホスファートナトリウムリン酸リボフラビンナトリウムビタミンB2リン酸エステルリボフラビンりん酸エステルナトリウムリボフラビン5'-りん酸ナトリウムビタミンB2りん酸エステルナトリウムリボフラビン5'-りん酸エステルナトリウムリボフラビン5'-りん酸水素ナトリウムリボフラビン5'-(りん酸ナトリウム)リボフラビンリン酸Ｎａナトリウム＝1-デオキシ-1-（7，8-ジメチル-2，4-ジオキソ-3，4-ジヒドロベンゾ［g］プテリジン-10（2H）-イル）-5-O-（ヒドロキシホスフィナト）-D-リビトールリボフラビン-5'-りん酸ナトリウム塩りん酸リボフラビンナトリウム塩 (〜70%)リボフラビン 5′-モノホスファート ナトリウム塩リボフラビンリン酸エステルナトリウム (JP17)リボフラビン5′-(りん酸ナトリウム)リボフラビン5′-りん酸水素ナトリウム{[(2R,3S,4S)-5-{7,8-ジメチル-2,4-ジオキソ-2H,3H,4H,10H-ベンゾ[g]プテリジン-10-イル}-2,3,4-トリヒドロキシペンチル]オキシ}(ソジオオキシ)ホスフィン酸FLAVIN MONONUCLEOTIDERIBOFLAVIN-5-PHOSPHATERIBOFLAVIN 5'-PHOSPHATE SODIUMRiboRiboflavin Phosphate Sodium Salt(2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-2,3,4-trihydroxypentyl dihydrogen phosphateTenofovir Impurity 155Vitamin B2 Sodium Phosphate
Riboflavin (phosphate sodium)957E53WV42NSC 759230Riboflavin monophosphate monosodium saltSodium (2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-2,3,4-trihydroxypentyl hydrogen phosphateMFCD00065362FMN-NaFLAVIN MONONUCLEOTIDE MONOSODIUM SALT [MI]

データベース識別子

CAS
130-40-5、22251-85-0
PubChem CID
23666409
DTXSID
DTXSID80889330
ChEBI
CHEBI:32098
UNII
957E53WV42
EC Number
204-988-6、244-868-0

物性

構造計算による物性

極性表面積
204 Ų
水素結合供与体数
5
水素結合受容体数
10
回転可能結合数
7
重原子数
32

実験および物理化学的性質

Physical DescriptionExists as the dihydrate: Yellow solid; [Merck Index] Yellow to orange hygroscopic solid; [JECFA]
Collision Cross Section197.2 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

物理化学的性質

融点
300 °C · >300°C
比旋光度
20 · [α]D20 +38～+43° (c=1.5, dil. HCl) (Calculated on dehydrous basis)
FEMA
2976 · 2976 | QUININE HYDROCHLORIDE
屈折率
41 ° · 41 ° (C=1.5, 5mol/L HCl)
貯蔵温度
2 · 2-8°C
溶解性
2 O: · H2O: 可溶50mg/mL、透明、オレンジ
化学的性質 · 1 件

化学的特性Riboflavin 5'-Monophosphate Sodium Salt is a yellow toorange-yellow, crystalline hygroscopic powder. It is odorless, and has a slightly bitter taste. It is soluble in water, and practically insoluble in ethanol(95), in chloroform and in diethyl ether. It is decomposed on exposure to light.

安全と法規制

GHS分類

GHS Classification · 3 件

This chemical does not meet GHS hazard criteria for 97% (65 of 67) of all reports.

Not Classified；Reported as not meeting GHS hazard criteria by 65 of 67 companies (only 3% companies provided GHS information). For more detailed information, please visit ECHA C&L website.

Aggregated GHS information provided per 67 reports by companies from 2 notifications to the ECHA C&L Inventory.；Reported as not meeting GHS hazard criteria per 65 of 67 reports by companies.；There is 1 notification provided by 2 of 67 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory Information · 2 件

Regulation (EC) No 1831/2003 (amended)

Riboflavin 5-phosphate sodium: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryMay cause irritation; Prolonged or repeated exposure may cause skin discoloration; [Sigma-Aldrich MSDS]
Hazard Classes and CategoriesNot Classified

法規制情報

Regulatory Information · 2 件

Regulation (EC) No 1831/2003 (amended)

Riboflavin 5-phosphate sodium: Does not have an individual approval but may be used under an appropriate group standard

安全データ

F
3-8-10
wgk
3
tsca
TSCA listed
hs_code
29362300
risk_code
36/38
hazard_code
Xi

化学と産業

用途と製造

UsesA bioactive form of riboflavin; [Merck Index] Used as a nutritional supplement; [FDA] Used as a coloring agent for foods; [JECFA]
Use ClassificationCosmetics -> Skin conditioning
General Manufacturing InformationRiboflavin 5'-(dihydrogen phosphate), sodium salt (1:1): ACTIVE
応用分野 · 4 件

用途薬理・生理作用研究用。

用途酵素研究用。

使用One of the bioactive forms of Riboflavin. Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, leafy vegetables. Richest natural source is yeast. Minute amounts present in all plant and animal cells. Vitamin (enzyme cofactor).

一般的な説明Riboflavin 5'-Monophosphate Sodium Salt Hydrate (Vitamin B2 Salt) may serve as both a carbon source and reducing agent for synthesising luminescent carbon dots and carbon-encapsulated metal (Au, Pt, Pd) particles. Simultaneous hydrothermal heating of B2salt and metal salt solutions yields water-soluble carbon dots in the supernatant and carbon-coated metal particles in the precipitate. The resulting carbon dots exhibit dual nitrogen and phosphorus doping, enhancing their luminescent properties, while the metal-loaded carbon particles hold significant potential for catalytic applications.

調製方法 · 1 件

純化方法Purify FMN by paper chromatography using tert-butanol/water, cutting out the main spot and eluting it with water. It can also be purified by adsorption onto an apo-flavodoxin column, followed by elution and freeze drying. It crystallises from aqueous acidic solution. [Mayhew & Strating Eur J Biochem 59 539 1976, Beilstein 26 III/IV 2555.]

上流・下流製品情報

上流原料

サプライヤー100 社

北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
河北九星化工产品有限公司13503103636 · [email protected]
上海如吉生物科技发展有限公司+86-21-65211385-8001 36031160 · [email protected]

補足説明

定義本品は、リン酸(*)とリボフラビン(*)のエステルのナトリウム塩であり、次の化学式で表される。参照表示名称：リン酸, リボフラビン

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