CAS 90693-88-2 Sodium 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (HCID 23692652)

基本情報

CAS: 90693-88-2
標準SMILES: CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](COP(=O)([O-])OC[C@H](N)C(=O)O)OC(=O)CCCCCCC/C=C\CCCCCCCC.[Na+]
InChIKey: RRLDZFIFYLDDLI-OLZOWLLTNA-N
分子式: C42H77NNaO10P
平均分子量: 810 g/mol

名称と識別子

優先名称: Sodium 1,2-dioleoyl-sn-glycero-3-phospho-L-serine
IUPAC: sodium [(2S)-2-amino-2-carboxyethyl] [(2R)-2,3-bis[[(Z)-octadec-9-enoyl]oxy]propyl] phosphate
英語名: 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodiuM salt)
分子式: C42H79NNaO10P
分子量: 812.05

名称と別名

90693-88-2Sodium 1,2-dioleoyl-sn-glycero-3-phospho-L-serineZBE12XT39T1,2-Dioleoyl-sn-glycero-3-phospho-serine, sodium salt1,2-Dioleoyl-sn-glycero-3-phospho-L-serine, sodium salt1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt)4,6,10-Trioxa-5-phosphaoctacos-19-enoic acid, 2-amino-5-hydroxy-11-oxo-8-(((9Z)-1-oxo-9-octadecenyl)oxy)-, 5-oxide, sodium salt (1:1), (2S,8R,19Z)-RefChem:10986231,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodiumUNII-ZBE12XT39T1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodium salt)DOPS sodium

名称をさらに表示

18:1 PS (DOPS)DOPS (18:1 PS)1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)1,2-Dioctadecenoyl-sn-glycero-3-PhosphoserineDioyl phosphatidylserine (sodium salt) (DOPS-NA)1,2-Dioleoyl-sn-glycero-3-phosphoserine sodium salt (DOPS Na)sodium O-(((R)-2,3-bis(oleoyloxy)propoxy)oxidophosphoryl)-L-serinate18:1 PS (DOPS)1,2-di - (9Z-octadecanoyl) - sn-glycero-3-phosphoyl-L-serine sodium salt

物性

構造計算による物性

極性表面積: 175 Å²
水素結合供与体数: 2
水素結合受容体数: 11
回転可能結合数: 42
重原子数: 55
形式電荷: 0
複雑度: 1,030

物理化学的性質

貯蔵温度: -20 °C · Store at -20°C
溶解性: 10 mg/ml · Chloroform: 10 mg/ml
外見: A crystalline solid
色: Light yellow to orange
水溶解度: soluble (Insoluble in ethanol and DMSO, soluble in Chloroform:Methanol:Water (65:25:4) at 5mg/mL)
InChIKey: RRLDZFIFYLDDLI-OLZOWLLTNA-N
SMILES: [C@H](COC(=O)CCCCCCC/C=C\CCCCCCCC)(OC(=O)CCCCCCC/C=C\CCCCCCCC)COP(O)(=O)OC[C@H](N)C(=O)O.[NaH] |&1:0,49,r|

安全と法規制

安全データ

wgk: WGK 3
ストレージクラス: 13 - Non Combustible Solids

化学と産業

応用分野 · 2 件

説明1,2-Dioleoyl-sn-glycero-3-PS (DOPS) is a phospholipid containing oleic acid (Item Nos. 90260 | 24659) at the sn-1 and sn-2 positions, respectively. Nanovesicles composed of DOPS and the lysosomal protein saposin C (SapC) are cytotoxic to SK-MEL-28 cells in vitro and decrease tumor volume in a squamous cell carcinoma mouse xenograft model. DOPS has been used in the formation of unilamellar vesicles to study the effect of curvature on membrane structure and in the formation of supported lipid bilayers to study the effects of various support materials on lipid redistribution between membrane leaflets.

使用1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodiuM salt) is a lipid being studied in the assembly and long-term stability of solid supported lipid bilayers from artificial and natural lipid mixtures.

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化合物ノート

読み込み中…

Sodium 1,2-dioleoyl-sn-glycero-3-phospho-L-serine