りん酸ジカリウム

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Dipotassium hydrogen phosphate is exempted from the requirement of a tolerance when used as a buffering agent in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops only.

Residues of potassium phosphate are exempted from the requirement of a tolerance when used as a buffer in accordance with good agricultural practices as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops or to raw agricultural commodities after harvest. /Potassium phosphate/

17 [mg/m3]

190 [mg/m3]

1100 [mg/m3]

The CIR Expert Panel concluded that the following 31 ingredients are safe in the present practices of use and concentration in cosmetics as described in this safety assessment, when formulated to be non-irritating...Dipotassium Phosphate...

Safe for use in cosmetics, with qualifications

ACUTE POTASSIUM INTOXICATION BY MOUTH IS RARE BECAUSE LARGE SINGLE DOSES USUALLY INDUCE VOMITING & BECAUSE IN ABSENCE OF PREEXISTING KIDNEY DAMAGE, POTASSIUM IS RAPIDLY EXCRETED. /POTASSIUM SALTS/

SIDE EFFECTS OF /ORAL/ POTASSIUM SALTS MAY INCLUDE NAUSEA, VOMITING, DIARRHEA, AND ABDOMINAL DISCOMFORT. /POTASSIUM SALTS/

CLINICAL SIGNS AND SYMPTOMS OF /ORAL/ POTASSIUM OVERDOSAGE INCLUDE PARESTHESIAS OF THE EXTREMITIES, LISTLESSNESS, MENTAL CONFUSIONS, WEAKNESS OR HEAVINESS OF THE LEGS, FLACCID PARALYSIS, COLD SKIN, GRAY PALLOR, PERIPHERAL VASCULAR COLLAPSE WITH FALL IN BLOOD PRESSURE, CARDIAC ARRHYTHMIAS, AND HEART BLOCK. /POTASSIUM SALTS/

/IN POTASSIUM POISONING/ RESPIRATIONS ARE INITIALLY ACCELERATED BUT SKELETAL MUSCLE WEAKNESS MAY ADVANCE TO STAGE OF PARALYSIS. /POTASSIUM SALTS/

For more Human Toxicity Excerpts (Complete) data for DIPOTASSIUM PHOSPHATE (6 total), please visit the HSDB record page.

INVESTIGATED BY PLEDGET TECHNIQUE IN 1 ESOPHAGEAL STUDY WITH CATS, PRODUCED EXTENSIVE NECROSIS & ULCERATION. INGESTION MAY PRODUCE OROPHARYNGEAL BURNS, ESOPHAGITIS & GASTRITIS ACCOMPANIED BY ULCERATION, BLEEDING & DIARRHEA.

AFTER ORAL ADMIN OF 0.8 G/KG BODY WT FOR 14 OR 38 WK DOGS VOMITED, WERE CACHECTIC, & HAD ELEVATED CREATININE & BLOOD UREA NITROGEN. RENAL DAMAGE WAS MOST MARKED @ 38 WK, THERE WERE DISSEMINATED ATROPHY (USUALLY OF PROXIMAL TUBLES), FOCAL SCAR TISSUE & NEPHROCALCINOSIS.

ORALLY POISONED ANIMALS DIED FROM RESP FAILURE SOMETIMES FOLLOWING CONVULSIONS & ... GASTROENTERITIS, DEHYDRATION OF ORGANS & EARLY RENAL TUBULAR NECROSIS. /POTASSIUM SALTS/

/ORALLY POISONED ANIMALS/ SURVIVORS HAD ANOREXIA, POLYDIPSIA, POLYURIA, FEVER, CONVULSIVE MOVEMENTS & GI DISTURBANCES DURING FIRST 24 HR, BUT RAPIDLY RECOVERED ... . /POTASSIUM SALTS/

For more Non-Human Toxicity Excerpts (Complete) data for DIPOTASSIUM PHOSPHATE (8 total), please visit the HSDB record page.

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 6 to 12 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Do not attempt to neutralize. Cover the skin burns with dry sterile dressings after decontamination ... . /Inorganic Bases/Alkaline Corrosives and Related Compounds/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in respiratory arrest. Early intubation, at the first signs of upper airway obstruction, may be necessary. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV of D5W TKO /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of pulmonary edema. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Consider drug therapy for pulmonary edema ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Inorganic Bases/Alkaline Corrosives and Related compounds/

1

PPRTV Current

4

PPRTV Current

FAO/WHO EXPERT COMMITTEE ON FOOD ADDITIVES...RECOMMENDED.../LEVELS/ FOR TOTAL DIETARY PHOSPHORUS...UNCONDITIONAL ACCEPTANCE LEVEL /OF LESS THAN 30 MG/KG BODY WT/ IS CONSIDERED SAFE IN ANY TYPE OF DIET...CONDITIONAL ACCEPTANCE LEVEL /OF 30-70 MG/KG BODY WT/ IS ACCEPTABLE ONLY WHEN DIETARY CALCIUM LEVEL IS HIGH /PHOSPHATES/

7.80e+04

1.20e+06

2.00e+04

1.5E+01(G)

1.00e+00

Volatile

2.30e+05

3.50e+06

6.00e+04

1.5E+01 (G)

1.00e+00

Volatile

Dipotassium phosphate used as a sequestrant in food for human consumption is generally recognized as safe when used in accordance with good manufacturing practice.

Dipotassium phosphate used as a sequestrant in animal drugs, feeds, and related products is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

Potassium phosphates (mono-, di-, and tribasic) are indirect food additives for use only as a component of adhesives. /Potassium phosphates (mono-, di-, and tribasic)/

Dipotassium hydrogen phosphate is exempted from the requirement of a tolerance when used as a buffering agent in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops only.

Residues of potassium phosphate are exempted from the requirement of a tolerance when used as a buffer in accordance with good agricultural practices as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops or to raw agricultural commodities after harvest. /Potassium phosphate/

CIR ingredient: Dipotassium Phosphate

Used as a buffering agent and corrosion inhibitor in anti-freeze, a culture nutrient for the production of antibiotics, a sequestrant, an emulsifier in cheeses, and a buffer in coffee creamers; Also used in specialty fertilizers, paper-processing aids, and saline cathartics; [HSDB] Used as yeast nutrient, humectant, and laboratory reagent; [CHEMINFO]

Pulp and Paper Processing [Category: Industry]

Buffering agent in anti-freeze; nutrient in the culturing of antibiotics

Sequestrant; emulsifier in specified cheeses

Most of the commercial output of dipotassium phosphate is used in conjunction with borates, nitrites, nitrates, and/or silicates as corrosion inhibitor systems in ethylene glycol antifreeze formulations. Its second largest use is as a buffer in coffee creamers to prevent casein protein precipitation by coffee acids. Other uses include specialty fertilizers, paper-processing aids, and saline cathartics.

(1973) PROBABLY GREATER THAN 5X10+9 G (USE)

(1975) 4.54-6.36X10+9 GRAMS (SUPPLY)

INJECTION, 2 MEQ OF POTASSIUM ION AND 1 MEQ OF HYDROGEN PHOSPHATE ION PER ML WITH BENZYL ALCOHOL 0.9%; 30 ML VIALS; POWDER NATIONAL FORMULARY.

Grades: commercial; pure; highest purity; NF /National Formulary/; FCC /Food Chemicals Codex/

Solid and 50% active solution

Food additives

Food Additives -> ACIDITY_REGULATOR; SEQUESTRANT; YEAST_FOOD -> JECFA Functional Classes

Food Additives -> ACIDITY_REGULATOR; SEQUESTRANT; YEAST_FOOD -> JECFA Functional Classes

Food Additives -> ACIDITY_REGULATOR; SEQUESTRANT; YEAST_FOOD -> JECFA Functional Classes

Food Additives -> ACIDITY_REGULATOR; SEQUESTRANT; YEAST_FOOD -> JECFA Functional Classes

Food Additives -> ACIDITY_REGULATOR; SEQUESTRANT; YEAST_FOOD -> JECFA Functional Classes

Phosphoric acid, potassium salt (1:2): ACTIVE

THE PROPERTIES OF /POTASSIUM PHOSPHATE/ ... DI-SALTS GIVE THEM EXCELLENT POTENTIAL AS FERTILIZERS, BUT HERETOFORE THEY HAVE RECEIVED SCANT ATTENTION BY THE INDUSTRY BECAUSE OF HIGH COSTS OF PRODUCTION.

... CAN INACTIVATE METALLIC IONS, WHICH ARE CAPABLE OF INTERFERING WITH NECESSARY FOOD-PROCESSING REACTIONS ... /INACTIVATION IS/ EITHER BY PPTN & REMOVING THEM FROM INTERFERENCE WITH DESIRED FOOD-PROCESSING REACTIONS OR BY COMPLEXING & MAINTAINING THEM IN SOL, BOUND STATE. /PHOSPHATES/