水銀(II)ジヨージド

If material involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty). Use water in flooding quantities as fog. Use foam, dry chemical or carbon dioxide. /Mercuric iodide; mercuric iodide, solution/

PROTECT FROM LIGHT.

Storage temperature: Ambient

Mercury spills should be cleaned up immediately by use of a special vacuum cleaner. Then the area should be washed with a dilute calcium sulfide solution. Small quantities of mercury can be picked up by mixing with copper metal granules. ... /Mercury/

Mercury removal from waste water can be accomplished by these processes: BMS process; Chlorine is added to the waste water, oxidizing any mercury present to the ionic state. The BMS adsorbent (an activated carbon concentrate of sulfur cmpd on its surface) is used to collect ionic mercury. The spent adsorbent is then distilled to recover the mercury, leaving a carbon residue for reuse or disposal. TMR IMAC Process; Waste water is fed into a reactor, whereby a slight excess of chlorine is maintained, oxidizing any mercury present to ionic mercury. The liquid is then passed through the TMR IMAC ion-exchange resin where mercury ions are adsorbed. The mercury is then stripped from the spent resin with hydrochloric acid solution. /Mercury cmpds/

SPILLED MERCURY CMPD OR SOLN CAN BE CLEANED UP BY ANY METHOD THAT DOES NOT CAUSE EXCESSIVE AIRBORNE CONTAMINATION OR SKIN CONTACT. /MERCURY COMPOUNDS/

1) Ventilate area of spill. 2) Collect spilled material for reclamation using commercially available mercury vapor depressants or specialized vacuum cleaners. /Inorganic mercury/

Personnel protection: Avoid breathing dusts, and fumes from burning material. Keep upwind. Avoid bodily contact with the material. ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. ... If contact with the material anticipated, wear appropriate chemical protective clothing. /Mercuric iodide; mercuric iodide solution/

If material not involved in fire: Keep material out of water sources and sewers. /Mercuric iodide; mercuric iodide solution/

Preventative measure: adequate ventilation; careful attention to good housekeeping, e.g., avoidance of spills, and prompt and proper cleaning if a spill occurs; all containers of mercury and its compounds should be kept tightly closed; should be washed on a regular basis with dilute calcium sulfide solution or other suitable reactant; floors should be nonporous; all workers directly involved in the plant operation should shower thoroughly each day before leaving. /Mercury compounds/

0.02 [mg/m3], as Hg (0.01 ppm, inhalable fraction and vapor (iodides))

8 hr Time Weighted Avg (TWA): 0.025 mg/cu m, skin /Mercury, elemental and inorganic forms, as Hg/

Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded. /Mercury, elemental and inorganic forms, as Hg/

A4: Not classifiable as a human carcinogen. /Mercury, elemental and inorganic forms, as Hg/

Biological Exposure Index (BEI): Determinant: total inorganic mercury in urine; Sampling Time: prior to shift; BEI:35 ug/g creatine. The determinant may be present in biological specimens collected from subjects who have not been occupationally exposed, at a concentration which could affect interpretation of the result. Such background concentrations are incorporated in the BEI value. /Mercury/

Biological Exposure Index (BEI): Determinant: total inorganic mercury in blood; Sampling Time: end of shift at end of workweek; BEI: 15 ug/L. The determinant may be present in biological specimens collected from subjects who have not been occupationally exposed, at a concentration which could affect interpretation of the result. Such background concentrations are incorporated in the BEI value. /Mercury/

Mercury mainly affects the nervous system. Exposure to high levels of metallic, inorganic, or organic mercury can permanently damage the brain, kidneys, and developing fetus. Effects on brain functioning may result in irritability, shyness, tremors, changes in vision or hearing, and memory problems. Acrodynia, a type of mercury poisoning in children, is characterized by pain and pink discoloration of the hands and feet. Mercury poisoning can also cause Hunter-Russell syndrome and Minamata disease. (L7)

High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through alterations in intracellular thiol status, mercury can promote oxidative stress, lipid peroxidation, mitochondrial dysfunction, and changes in heme metabolism. Mercury is known to bind to microsomal and mitochondrial enzymes, resulting in cell injury and death. For example, mercury is known to inhibit aquaporins, halting water flow across the cell membrane. It also inhibits the protein LCK, which causes decreased T-cell signalling and immune system depression. Mercury is also believed to inhibit neuronal excitability by acting on the postsynaptic neuronal membrane. It also affects the nervous system by inhibiting protein kinase C and alkaline phosphatase, which impairs brain microvascular formation and function, as well as alters the blood-brain barrier. Mercury also produces an autoimmune response, likely by modification of major histocompatibility complex (MHC) class II molecules, self peptides, T-cell receptors, or cell-surface adhesion molecules. (L7, A8, A25, A26)

A 31 year old inhabitant of French Guiana was prescribed mercuric iodide per os for a half month. Shortly before the end of the treatment he developed fasciculations in the trunk and particularly the lower limb muscles, distal painful paresthesias with vasomotor disorders, episodes of excessive perspiration and palmoplantar erythema, moderate fluctuating hypertension, progressive loss of weight and irritability with insomnia. Clinical and electrical signs of neuropathy were lacking. The clinical picture was that of Morvan's fibrillary chorea with acrodynia, the conditions of onset strongly suggesting a mercurial intoxication. Blood and particularly urine mercury levels were elevated. Administration of dimercaprol considerably increased urinary excretion of mercury and there was progressive improvement and finally recovery after two months of dimercaprol treatment.

MERCURIC IODIDE INJECTED INTO ANTERIOR CHAMBER OF RABBITS HAS CAUSED PURULENT EXUDATION AND INFLAMMATION.

DOGS & CATS ARE PARTICULARLY SUSCEPTIBLE TO TOXIC EFFECTS OF HG FROM MERCURIAL OINTMENTS, BOTH DUE TO DIRECT ABSORPTION & LICKING OF PARTS TO WHICH OINTMENT HAS BEEN APPLIED. POISONING IN CATTLE HAS ALSO BEEN RECORDED AFTER USE OF OINTMENTS CONTAINING ... MERCURIC IODIDE ...

Mercuric iodide (HgI2), mercuric chloride (HgCl2) ... were administered via stomach to males and females (1-20 days of pregnancy) to study the toxic effects on the male gonads and embryogenesis, respectively. In the second series, mercury (Hg) salts were given to male rats daily for 2 mo. All the cmpd were markedly embryotoxic and the severity depended on the dose and the intake schedule. ... HgI2 was more toxic than HgCl2. These materials characteristically decr the size of the placenta. They showed no teratogenic activity. The embryolethal effect of HgI2 (1/8 LD50) was most pronounced when it was administered during 1-4 days of pregnancy. The embryo deaths were not practically any different from the control if HgI2 was administered on other days. Thus, these Hg cmpd are sufficiently effective with reference to intrauterine development (cause embryo death but show no teratogenicity), whereas the embryolethal effect is most evident during the initial stage of embryogenesis.

Among mercuric iodide, mercuric chloride, and mercuric ammonium chloride, the acute toxic concn to monolayer cell cultures (Hepl-2, Vero and amnion) was the lowest for mercuric iodide (HgI2) (cell degeneration), followed by that of mercuric chloride (HgCl2). The Hg(II) compounds belonged to class II type materials (highly toxic). The sensitivity of the cell lines to the Hg was practically similar; only human amnion cells were somewhat more sensitive than the remaining ones. The Hg inhibited the cell growth and multiplication and the max effect was observed by 48 hr. The investigated cmpd inhibited monoamine oxidase activity in the hepatic mitochondria at 10-2M.

For more Non-Human Toxicity Excerpts (Complete) data for MERCURIC IODIDE (6 total), please visit the HSDB record page.

D009; A solid waste containing mercury may or may not become characterized as a hazardous waste when subjected to the Toxicity Characteristic Leaching Procedure listed in 40 CFR 261.24, and if so characterized, must be managed as a hazardous waste. /Mercury/

Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Mercuric iodide is included on this list.