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ひ酸水素ジアンモニウム

Ammonium arsenate

HCID 24574
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基本情報概要名称と識別子物性安全と法規制化学と産業関連反応化合物ノート
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基本情報

CAS
7784-44-3
標準SMILES
O=[As]([O-])([O-])O.[NH4+].[NH4+]
InChIKey
XPVHUBFHKQQSDA-UHFFFAOYSA-N
分子式
(NH4)2HAsO4
平均分子量
176 g/mol
単同位体質量
175.977826

概要

Ammonium arsenate appears as a white crystalline solid. Toxic by ingestion.

名称と識別子

優先名称
Ammonium arsenate
IUPAC
diazanium;hydrogen arsorate
現地名
ひ酸水素ジアンモニウム
英語名
AMMONIUM ARSENATE
分子式
AsH6NO4
分子量
158.97

名称と別名

AMMONIUM ARSENATEAmmonium acid arsenate7784-44-3Diammonium hydrogenarsenateDibasic ammonium arsenateDIAMMONIUM ARSENATESecondary ammonium arsenateDiammonium hydrogen arsenateDiammonium monohydrogen arsenateUN1546Arsenic acid (H3AsO4), diammonium saltdiammonium hydrogen arsorate
名称をさらに表示
ひ酸水素ジアンモニウムジアンモニウムヒ酸塩ヒ酸アンモニウム((NH4)2AsHO4)ヒ酸一水素二アンモニウム砒酸アンモニウムアザニウミル 水素 (アザニウミルオキシ)アルソナートヒ酸二アンモニウムhydrogen arsorateammoniumacidarsenateAMMONIUM ARSENATE (DI)dibasicammoniumarsenatesecondaryammoniumarsenateAMMONIUM ARSENATE (ORTHO)Ammonium hydrogenarsenateAMMONIUM ARSENATE TRIBASIC
AMMONIUM ARSENATE, (SOLID)AMMONIUM ARSENATE, [SOLID]Ammonium arsenic acidRefChem:557658(NH4)3AsO4AMMONIUM ARSENATE ((NH4)2ASHO4)AMMONIUM ARSENATE ((NH4)2HASO4)diazanium;hydrogen arsorate

物性

構造計算による物性

極性表面積
85.4 Ų
水素結合供与体数
3
水素結合受容体数
4
回転可能結合数
0
重原子数
7
形式電荷
0
複雑度
46.5

実験および物理化学的性質

Chemical Classes · 2 件

Metals -> Arsenic Compounds, Inorganic

Carcinogens

Density2.0 g/cm³
SolubilitySolubility in water: good
Physical Description · 3 件

Ammonium arsenate appears as a white crystalline solid. Toxic by ingestion.

White solid, soluble in water; Decomposes in hot water; [Hawley]

COLOURLESS CRYSTALS WITH CHARACTERISTIC ODOUR.

物理化学的性質

融点
10 · decomposes [CRC10]
比重(密度)
1.99 · 1.990
溶解性
2 O · soluble in H2O
外見
powder
色
white
水溶解度
2 Oによって分解される可溶性H2O · 高温のH2Oによって分解される可溶性H2O [HAW93]
EPAの化学物質情報
Arsenic acid (H3AsO4), diammonium salt (7784-44-3)

化学的性質

化学的特性Ammonium arsenate a combustible, white powder or plate-like colorless crystal.

安全と法規制

安全情報は参考情報です。供給元の安全データシート(SDS)、適用法令、専門家による評価に代わるものではありません。

危険有害性情報

Regulatory Information · 2 件

Restricted substance: Diammonium hydrogenarsenate

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

DOT LabelPoison
Fire Hazards · 3 件

Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:

· Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.

Health Hazards · 2 件

Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:

· Highly toxic, may be fatal if inhaled, ingested or absorbed through skin.

Hazards SummaryA skin, eye, and respiratory tract irritant; May cause arsenic poisoning; [ICSC] Toxic by ingestion; [MSDSonline] See Arsenic and the linked occupational diseases.
DOT ID and Guide1546 151
Reactive GroupSalts, Acidic
EC ClassificationSymbol: T, N; R: 45-23/25-50/53; S: 53-45-60-61; Note: A, E
UN ClassificationUN Hazard Class: 6.1; UN Pack Group: II
Reactivity ProfileSolutions of AMMONIUM ARSENATE are acidic. They neutralize bases in reactions that generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acids.
Chemical Dangers · 1 件

化学と産業

薬理情報

Metabolism/Metabolites · 1 件

Arsenic is absorbed mainly by inhalation or ingestion, as to a lesser extent, dermal exposure. It is then distributed throughout the body, where it is reduced into arsenite if necessary, then methylated into monomethylarsenic (MMA) and dimethylarsenic acid (DMA) by arsenite methyltransferase. Arsenic and its metabolites are primarily excreted in the urine. Arsenic is known to induce the metal-binding protein metallothionein, which decreases the toxic effects of arsenic and other metals by binding them and making them biologically inactive, as well as acting as an antioxidant. (L20)

用途と製造

UsesIt is used as herbicide, insecticide,and rodenticide (L926).

応用分野

一般的な説明A white crystalline solid. Toxic by ingestion.

サプライヤー5 社

武汉易泰科技有限公司上海分公司18930552037 · [email protected]
陕西缔都医药化工有限公司+86-29-81139210 +86-17392587031 · [email protected]
厦门盈融达化工有限公司+86-0592-6210733 · [email protected]
爆牛贸易重庆有限公司+86-023-6139-8061 +86-86-13650506873 · [email protected]
陕西缔都医药化工有限公司029-029-029-81148696 18161915376 · [email protected]

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化合物ノート

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データベース識別子

CAS
7784-44-3
PubChem CID
24574
DTXSID
DTXSID0036895
EC Number
232-067-9

Decomposes on heating. This produces toxic and corrosive fumes. Reacts with acids. This produces toxic arsine gas (see ICSC 0222). Attacks many metals such as iron, aluminium and zinc in the presence of water. This produces toxic fumes of arsenic (see ICSC 0013) and arsine (see ICSC 0222). Reacts with strong oxidants and bases. This produces toxic and corrosive fumes including ammonia.

Packaging and LabellingDo not transport with food and feedstuffs.

安全と保護具

Fire Fighting · 2 件

Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:

In case of fire in the surroundings, use appropriate extinguishing media.

First Aid Measures · 4 件

Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap. Seek medical attention if you feel unwell.

Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer for medical attention.

Rinse mouth. Refer immediately for medical attention.

Accidental Release Measures · 2 件

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.

First Aid · 2 件

Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:

General First Aid:

Safe Storage · 1 件

Provision to contain effluent from fire extinguishing. Separated from acids, strong oxidants, bases and food and feedstuffs. Well closed. Dry. Do NOT store or transport in containers made from metal. Store in an area without drain or sewer access.

Exposure Control and Personal Protection · 2 件

· Wear positive pressure self-contained breathing apparatus (SCBA).

Biological Exposure Indices (BEI) [ACGIH] - Inorganic arsenic plus methylated metabolites in urine = 35 ug As/L; end of workweek;

Nonfire Spill ResponseExcerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:
Spillage Disposal · 1 件

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Vacuum with specialist equipment or carefully sweep into containers. Carefully collect remainder. Then store and dispose of according to local regulations.

Isolation and Evacuation · 2 件

Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:

Immediate precautionary measure

Eye PreventionWear face shield or eye protection in combination with breathing protection if powder.
Inhalation RiskA harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered.
Skin PreventionProtective gloves. Protective clothing.

毒性情報

Treatment · 1 件

Arsenic poisoning can be treated by chelation therapy, using chelating agents such as dimercaprol, EDTA or DMSA. Charcoal tablets may also be used for less severe cases. In addition, maintaining a diet high in sulfur helps eliminate arsenic from the body. (L20)

Health EffectsArsenic poisoning can lead to death from multi-system organ failure, probably from necrotic cell death, not apoptosis. Arsenic is also a known carcinogen, esepcially in skin, liver, bladder and lung cancers. (T1, L20)
Adverse EffectsNeurotoxin - Sensorimotor
Exposure Routes · 2 件

The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Oral (L2) ; inhalation (L2); dermal (L2)

Toxicity Summary · 1 件

Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by competing with phosphate it uncouples oxidative phosphorylation, thus inhibiting energy-linked reduction of NAD+, mitochondrial respiration, and ATP synthesis. Hydrogen peroxide production is also increased, which might form reactive oxygen species and oxidative stress. Arsenic's carginogenicity is influenced by the arsenical binding of tubulin, which results in aneuploidy, polyploidy and mitotic arrests. The binding of other arsenic protein targets may also cause altered DNA repair enzyme activity, altered DNA methylation patterns and cell proliferation. (T1, A17)

Signs and Symptoms · 4 件

Cough. Sore throat.

Redness. Pain.

Abdominal pain. Diarrhoea. Vomiting. Burning sensation in the throat and chest. Headache. Weakness. Shock or collapse.

Exposure to lower levels of arsenic can cause nausea and vomiting, decreased production of red and white blood cells, abnormal heart rhythm, damage to blood vessels, and a sensation of burn (T1).

ICSC Environmental DataThe substance is toxic to aquatic organisms. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal.
Carcinogen Classification1, carcinogenic to humans. (L135)

安全データ

ridadr
UN 1546
hs_code
28429090
hazard_class
6.1
packing_group
II