7784-44-3O=[As]([O-])([O-])O.[NH4+].[NH4+]XPVHUBFHKQQSDA-UHFFFAOYSA-NAmmonium arsenate appears as a white crystalline solid. Toxic by ingestion.
Metals -> Arsenic Compounds, Inorganic
Carcinogens
Ammonium arsenate appears as a white crystalline solid. Toxic by ingestion.
White solid, soluble in water; Decomposes in hot water; [Hawley]
COLOURLESS CRYSTALS WITH CHARACTERISTIC ODOUR.
化学的特性Ammonium arsenate a combustible, white powder or plate-like colorless crystal.
安全情報は参考情報です。供給元の安全データシート(SDS)、適用法令、専門家による評価に代わるものではありません。
Restricted substance: Diammonium hydrogenarsenate
The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:
· Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.
Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:
· Highly toxic, may be fatal if inhaled, ingested or absorbed through skin.
Arsenic is absorbed mainly by inhalation or ingestion, as to a lesser extent, dermal exposure. It is then distributed throughout the body, where it is reduced into arsenite if necessary, then methylated into monomethylarsenic (MMA) and dimethylarsenic acid (DMA) by arsenite methyltransferase. Arsenic and its metabolites are primarily excreted in the urine. Arsenic is known to induce the metal-binding protein metallothionein, which decreases the toxic effects of arsenic and other metals by binding them and making them biologically inactive, as well as acting as an antioxidant. (L20)
一般的な説明A white crystalline solid. Toxic by ingestion.
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読み込み中…
7784-44-3DTXSID0036895Decomposes on heating. This produces toxic and corrosive fumes. Reacts with acids. This produces toxic arsine gas (see ICSC 0222). Attacks many metals such as iron, aluminium and zinc in the presence of water. This produces toxic fumes of arsenic (see ICSC 0013) and arsine (see ICSC 0222). Reacts with strong oxidants and bases. This produces toxic and corrosive fumes including ammonia.
Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:
In case of fire in the surroundings, use appropriate extinguishing media.
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Seek medical attention if you feel unwell.
Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer for medical attention.
Rinse mouth. Refer immediately for medical attention.
· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.
· Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.
Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:
General First Aid:
Provision to contain effluent from fire extinguishing. Separated from acids, strong oxidants, bases and food and feedstuffs. Well closed. Dry. Do NOT store or transport in containers made from metal. Store in an area without drain or sewer access.
· Wear positive pressure self-contained breathing apparatus (SCBA).
Biological Exposure Indices (BEI) [ACGIH] - Inorganic arsenic plus methylated metabolites in urine = 35 ug As/L; end of workweek;
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Vacuum with specialist equipment or carefully sweep into containers. Carefully collect remainder. Then store and dispose of according to local regulations.
Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:
Immediate precautionary measure
Arsenic poisoning can be treated by chelation therapy, using chelating agents such as dimercaprol, EDTA or DMSA. Charcoal tablets may also be used for less severe cases. In addition, maintaining a diet high in sulfur helps eliminate arsenic from the body. (L20)
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.
Oral (L2) ; inhalation (L2); dermal (L2)
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by competing with phosphate it uncouples oxidative phosphorylation, thus inhibiting energy-linked reduction of NAD+, mitochondrial respiration, and ATP synthesis. Hydrogen peroxide production is also increased, which might form reactive oxygen species and oxidative stress. Arsenic's carginogenicity is influenced by the arsenical binding of tubulin, which results in aneuploidy, polyploidy and mitotic arrests. The binding of other arsenic protein targets may also cause altered DNA repair enzyme activity, altered DNA methylation patterns and cell proliferation. (T1, A17)
Cough. Sore throat.
Redness. Pain.
Abdominal pain. Diarrhoea. Vomiting. Burning sensation in the throat and chest. Headache. Weakness. Shock or collapse.
Exposure to lower levels of arsenic can cause nausea and vomiting, decreased production of red and white blood cells, abnormal heart rhythm, damage to blood vessels, and a sensation of burn (T1).