基本情報
- 標準SMILES
O.O.O.O.O.O.O.O=S(=O)([O-])[O-].[Mg+2]- InChIKey
WRUGWIBCXHJTDG-UHFFFAOYSA-L- 分子式
- Mg.S.O4.7H2O
- 平均分子量
- 246.48 g/mol
- 単同位体質量
- 246.01072397
概要
Magnesium sulfate heptahydrate is a hydrate that is the heptahydrate form of magnesium sulfate. It has a role as a laxative and a cathartic. It is a magnesium salt and a hydrate. It contains a magnesium sulfate.
名称と識別子
- 優先名称
- Magnesium Sulfate Heptahydrate
- IUPAC
- magnesium;sulfate;heptahydrate
- 現地名
- 硫酸マグネシウム·7水和物
- 英語名
- Magnesium sulfate heptahydrate
- 分子式
- Mg.O4S.7H2O
- 分子量
- 246.47
名称と別名
名称をさらに表示
データベース識別子
- CAS
10034-99-8、14457-55-7- PubChem CID
- 24843
- DTXSID
DTXSID5040544- ChEBI
CHEBI:31795- UNII
- SK47B8698T
- EC Number
- 600-073-4、913-387-4
物性
構造計算による物性
- 極性表面積
- 95.6 Ų
- 水素結合供与体数
- 7
- 水素結合受容体数
- 11
- 回転可能結合数
- 0
- 重原子数
- 13
- 形式電荷
- 0
- 複雑度
- 62.2
実験および物理化学的性質
物理化学的性質
- 融点
- 1124 °C · 1124°C
- 比重(密度)
- 2.66 · 2.66
- 蒸気密度
- 0.01 · <0.01 (vs air)
- 蒸気圧
- 0.1 mm · <0.1 mm Hg ( 20 °C)
- 屈折率
- 1.433 · 1.433
- 貯蔵温度
- 5 °C · Store at +5°C to +30°C.
- 溶解性
- 2 O: · H2O: 1M at20℃、透明、無色
- 外見
- 個体
- 比重
- 1.68 · 1.68
- 色
- 白い
- PH
- 5 · 5.0-8.0 (25℃, 50mg/mL in H2O)
- 臭い (Odor)
- Odorless
- 水溶解度
- 水と酸に溶ける。アルコールおよびグリセロールにわずかに溶ける。
- Merck
- 14 · 14,5691
- Dielectric constant
- 8.2 · 8.2(Ambient)
- 安定性
- 安定。不燃性。空気に触れると徐々に劣化することがあります。
- 化粧品成分の機能
- 増量剤
- InChI
- 1S/Mg.H2O4S.7H2O/c;1-5(2,3)4;;;;;;;/h;(H2,1,2,3,4);7*1H2/q+2;;;;;;;;/p-2
- InChIKey
- WRUGWIBCXHJTDG-UHFFFAOYSA-L
- SMILES
- O.O.O.O.O.O.O.[Mg++].[O-]S([O-])(=O)=O
- LogP
- -1.031 · -1.031 (est)
- CAS データベース
- 10034 · 10034-99-8(CAS DataBase Reference)
- NISTの化学物質情報
- magnesium sulfate heptahydrate(10034-99-8)
- EPAの化学物質情報
- Magnesium sulfate heptahydrate (10034-99-8)
化学的性質
化学的特性White or almost white, crystalline powder or brilliant, colourless crystals.
安全と法規制
GHS分類
GHS Classification
This chemical does not meet GHS hazard criteria for 100% (424 of 424) of all reports.
Not Classified
Aggregated GHS information provided per 424 reports by companies from 2 notifications to the ECHA C&L Inventory.
This chemical does not meet GHS hazard criteria for 100% (2 of 2) of all reports.
Not Classified
Aggregated GHS information provided per 2 reports by companies from 1 notifications to the ECHA C&L Inventory.
危険有害性情報
Regulatory Information
Chemical: Sulfuric acid, magnesium salt, heptahydrate
Sulfuric acid magnesium salt (1:1), heptahydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Sulfuric acid magnesium salt (1:1), heptahydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Sulfuric acid magnesium salt (1:1), heptahydrate: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and Categories
Not Classified
Not Classified
安全と保護具
Protective Action Criteria (PAC)
1.2 [mg/m3]
13 [mg/m3]
81 [mg/m3]
安全データ
- wgk
- 1
- tsca
- Yes
- rtecs
- OM4508000
- 毒性
- man,TDLo,oral,183mg/kg/4H-I (183mg/kg),GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA",Journal of Toxicology, Clinical Toxicology. Vol. 20, Pg. 107, 1983.
- hs_code
- 28332100
- risk_code
- 36/37/38
- hazard_code
- Xi
- safety_code
- 24/25-36-26
- ストレージクラス
- 13 - Non Combustible Solids
化学と産業
薬理情報
FDA Pharmacological Classification
50% MAGNESIUM SULFATE
Increased Large Intestinal Motility [PE]; Stimulation Large Intestine Fluid/Electrolyte Secretion [PE]; Inhibition Small Intestine Fluid/Electrolyte Absorption [PE]; Magnesium Ion Exchange Activity [MoA]; Osmotic Laxative [EPC]; Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Activity [MoA]; Calculi Dissolution Agent [EPC]
EPSOM SALT
Calculi Dissolution Agent [EPC]; Osmotic Activity [MoA]; Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Laxative [EPC]; Magnesium Ion Exchange Activity [MoA]; Inhibition Small Intestine Fluid/Electrolyte Absorption [PE]; Stimulation Large Intestine Fluid/Electrolyte Secretion [PE]; Increased Large Intestinal Motility [PE]
MAGNESIA SULPHURICA
Calculi Dissolution Agent [EPC]; Osmotic Activity [MoA]; Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Laxative [EPC]; Magnesium Ion Exchange Activity [MoA]; Inhibition Small Intestine Fluid/Electrolyte Absorption [PE]; Stimulation Large Intestine Fluid/Electrolyte Secretion [PE]; Increased Large Intestinal Motility [PE]
MeSH Pharmacological Classification
Compounds capable of relieving pain without the loss of CONSCIOUSNESS.
Agents capable of inducing a total or partial loss of sensation, especially tactile sensation and pain. They may act to induce general ANESTHESIA, in which an unconscious state is achieved, or may act locally to induce numbness or lack of sensation at a targeted site.
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
Drugs used to prevent SEIZURES or reduce their severity.
A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
Drugs that prevent preterm labor and immature birth by suppressing uterine contractions (TOCOLYSIS). Agents used to delay premature uterine activity include magnesium sulfate, beta-mimetics, oxytocin antagonists, calcium channel inhibitors, and adrenergic beta-receptor agonists. The use of intravenous alcohol as a tocolytic is now obsolete.
用途と製造
Use Classification
EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives
Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern
応用分野
解説水溶性の苦味を有する無色結晶,MgSO4.無水塩のほか,一,二,四,五,六,七および十二水和物が知られている.もっともふつうなのは七水和物で,シャリ塩またはエプソム塩とよばれる.古くから緩下剤として知られる.紙の充填剤,耐火剤,媒染剤,医薬品,マグネシウム肥料として用いられる.
用途肥料、耐火剤、陶磁器
用途紙の充てん剤、絹の増加量剤、耐火綿布の製造、媒染剤、医薬として用いられる。
用途高純度金属化合物。
用途食品添加物。
説明In addition to its use in foods as a flavor enhancer, nutrient supplement and processing aid, magnesium sulfate (as Epsom salt) is employed in over-the-counter preparations as a laxative. As a legend (prescription drug) it has been used as an anticonvulsant and electrolyte replenisher.
使用Magnesium sulfate heptahydrate has been used:as a component in Kreb′s Ringer bufferas a component in minimal medium to culture Ralstonia solanacearumin the preparation of maceration solution for Lamb′s lettuce cell isolation and isotonic glucose buffer
一般的な説明Magnesium sulfate heptahydrate is hydroscopic and is vulnerable to warm temperatures.
上流・下流製品情報
上流原料
下流製品
サプライヤー50 社
補足説明
定義本品は、硫酸(*)のマグネシウム塩であり、次の化学式で表される。参照表示名称:硫酸
定義Epsomite: a mineral form of magnesiumsulphate heptahydrate,MgSO4.7H2O.
関連反応
関連ノート
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