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二過マンガン酸カルシウム
二過マンガン酸カルシウム · 過マンガン酸カルシウム · ヘキサオキソ-2,4-ジオキサ-1,5-ジマンガナ-3-カルカペンタン · acerdol · dipermanganate · kaliumpermanganat · permanganatocalcico · CAICIUM PERMANGANATE
識別子と物理属性
| CAS No. | 10118-76-0 |
|---|---|
| 分子式 | CaMn2O8 |
| 平均分子量 | 277.95 g/mol |
| 単同位体質量 | 277.79799814 g/mol |
| SMILES | [Ca+2].[O]=[Mn](=[O])(=[O])[O-].[O]=[Mn](=[O])(=[O])[O-] |
| InChIKey | HYSMCTNXSYZEHS-UHFFFAOYSA-N |
| PubChem CID | 24959 |
| EC No. | 233-322-7 |
| DTXSID | DTXSID001015791 |
| 現地名 | 二過マンガン酸カルシウム |
化学・物理的性質
| 極性表面積 | 149 |
|---|---|
| 水素結合供与体数 | 0 |
| 水素結合受容体数 | 8 |
| 回転可能結合数 | 0 |
| 重原子数 | 11 |
| 形式電荷 | 0 |
| 複雑度 | 95.8 |
| 物質分類 | Other Classes -> Inorganic Oxidizing Agents |
| 密度 | 2.4 g/cu cm2.400 |
| Color/Form | Violet or dark-purple deliquescent crystals |
| 溶解度 | Freely soluble in waterreacts with ethanol非常に溶けやすいH2Oアルコール分解 [MER06] |
| Physical Description | Calcium permanganate is a purple crystalline solid. It is used as a disinfectant and deodorizer, in water purification, and for many other uses.Violet to purple crystals (tends to adsorb water from air and become liquid)[HSDB] |
| Other Experimental Properties | Decomposes in alcoholStrong oxidizer /tetrahydrate/Decomposes 130-40 °C /Tetrahydrate/PURPLE CRYSTALSDENSITY: 2.4331 G SOL IN 100 CC WATER @ 14 °C338 G SOL IN 100 CC WATER @ 25 °CSOL IN AMMONIUM HYDROXIDE /PENTAHYDRATE/ |
| 外観・状態 | 紫色の吸湿性結晶 |
| 色 | purp hygroscopic crystals, crystalline |
| EPAの化学物質情報 | Permanganic acid (HMnO4), calcium salt (10118-76-0) |
化学的特性
violet or dark purple, deliquescent crystal(s); made by reacting KMnO4 and CaCl2; used in the textile industry, to sterilize water, and as a deodorizer [HAW93] [MER06]
安全性と法規制
| 輸送ラベル（DOT） | Oxidizer |
|---|---|
| 火災危険 | Excerpt from ERG Guide 140 [Oxidizers]:CAUTION: Ammonium nitrate products may explode if involved in fire or contaminated with hydrocarbons (fuels), organic matter, other contaminants or when hot molten and contained. Treat as an explosive (GUIDE 112). |
| 健康有害性 | Excerpt from ERG Guide 140 [Oxidizers]:· Inhalation, ingestion or contact (skin, eyes) with vapors or substance may cause severe injury, burns or death. |
| 有害性の概要 | Very toxic by ingestion, inhalation, or skin absorptionCan cause skin burns[CAMEO] Potassium permanganate crystals and concentrated solutions are corrosive (release potassium hydroxide when contact water)Permanganates can induce methemoglobinemia after ingestion[Olson, p. 133] See Manganese and linked occupational diseases. |
| 輸送番号・ガイド（DOT） | 1456 140 |
| 反応性グループ | Oxidizing Agents, Strong |
| Reactivity Alerts | Strong Oxidizing Agent |
| OSHA Standards | Permissible Exposure Limit: Table Z-1 Ceiling value: 5 mg/cu m. /Manganese cmpd (as Mn)/ |
| Reactivity Profile | CALCIUM PERMANGANATE is an oxidizing agent. Noncombustible but it will accelerate the burning of combustible material. If the combustible material is finely divided the mixture may be explosive. Contact with liquid combustible materials may result in spontaneous ignition. Contact with sulfuric acid may cause fires or explosions. Mixtures with acetic acid or acetic anhydride can explode if not kept cold [Von Schwartz 1918 p. 34 ]. Explosions can occur when calcium permanganate that has been treated with sulfuric acid comes in contact with benzene, carbon disulfide, diethyl ether, ethyl alcohol, petroleum, or other organic matter. |
| 大気基準 | Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Calcium permanganate is included on this list.... Substances for which a Federal Register notice has been published that included consideration of the serious health effects, including cancer, form ambient air exposure to the substance. Manganese (50 FR 32627Aug. 13, 1985) is included on this list. /Manganese/ |
| DOT Emergency Guidelines | /GUIDE 140: OXIDIZERS/ Fire or Explosion: These substances will accelerate burning when involved in a fire. Some may decompose explosively when heated or involved in a fire. May explode from heat or contamination. Some will react explosively with hydrocarbons (fuels). May ignite combustibles (wood, paper, oil, clothing, etc.). Containers may explode when heated. Runoff may create fire or explosion hazard./GUIDE 140: OXIDIZERS/ Health: Inhalation, ingestion or contact (skin, eyes) with vapors or substance may cause severe injury, burns or death. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may cause pollution./GUIDE 140: OXIDIZERS/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering./GUIDE 140: OXIDIZERS/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing will only provide limited protection.For more DOT Emergency Guidelines (Complete) data for CALCIUM PERMANGANATE (8 total), please visit the HSDB record page. |
| DOT Hazard Classification | Calcium permanganateUN1456Div 5.1 Oxidizer (49 eCFR § 173.127)PG II: the degree of danger presented by the material is medium |
| 消火 | Excerpt from ERG Guide 140 [Oxidizers]: |
| 漏出応急措置 | · CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.· Keep combustibles (wood, paper, oil, etc.) away from spilled material. |
| 応急処置 | Excerpt from ERG Guide 140 [Oxidizers]:General First Aid: |
| 暴露管理・個人防護 | · Wear positive pressure self-contained breathing apparatus (SCBA).TIH (Toxic Inhalation Hazard) - Term used to describe gases and volatile liquids that are toxic when inhaled. Some are TIH materials themselves, e.g., chlorine, and some release TIH gases when spilled in water, e.g., chlorosilanes. [ERG 2016].0.2 [mg/m3], as Mn (inhalable fraction), 0.02 mg/m3, as Mn (respirable fraction)[German Research Foundation (DFG)] |
| 消火手順 | If material on fire or involved in fire: Flood with water. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible.Evacuation: If fire becomes uncontrollable - consider evacuation of one-half (1/2) mile radius. |
| 保管条件 | KEEP TIGHTLY CLOSED. |
| 非火災時の漏出対応 | Excerpt from ERG Guide 140 [Oxidizers]: |
| 処分方法 | SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices. |
| Preventive Measures | SRP: Local exhaust ventilation should be applied wherever there is an incidence of point source emissions or dispersion of regulated contaminants in the work area. Ventilation control of the contaminant as close to its point of generation is both the most economical and safest method to minimize personnel exposure to airborne contaminants.WHEN USING WITH STRONG ACIDS TO DESTROY ORGANIC MATTER, PERFORM REACTION BEHIND SAFETY BARRIER. /PERMANGANATES/If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers.Personnel protection: Avoid breathing dusts. Avoid bodily contact with the material. ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. ... |
| Isolation and Evacuation | Excerpt from ERG Guide 140 [Oxidizers]:Immediate precautionary measure |
| Minimum Risk Level | Chronic Inhalation: 0.0003 mg/m3 (L134) |
| Threshold Limit Values (TLV) | 0.02 [mg/m3], as Mn (respirable fraction), 0.1 mg/m3, as Mn (inhalable fraction)8 hr Time Weighted Avg: 0.2 mg/cu m /Manganese and inorganic compounds, as Mn/Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded. /Manganese and inorganic compounds, as Mn/ |
| Treatment | EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration. |
| 健康影響 | Manganese mainly affects the nervous system and may cause behavioral changes and other nervous system effects, which include movements that may become slow and clumsy. This combination of symptoms when sufficiently severe is referred to as “manganism”. (L228) |
| 有害作用 | Neurotoxin - Parkinsonism |
| 暴露経路 | Oral (L228)inhalation (L228) |
| 毒性の概要 | Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particularily the globus pallidus of the basal ganglia. It is believed that the manganese ion, Mn(II), enhances the autoxidation or turnover of various intracellular catecholamines, leading to increased production of free radicals, reactive oxygen species, and other cytotoxic metabolites, along with a depletion of cellular antioxidant defense mechanisms, leading to oxidative damage and selective destruction of dopaminergic neurons. In addition to dopamine, manganese is thought to perturbations other neurotransmitters, such as GABA and glutamate. In order to produce oxidative damage, manganese must first overwhelm the antioxidant enzyme manganese superoxide dismutase. The neurotoxicity of Mn(II) has also been linked to its ability to substitute for Ca(II) under physiological conditions. It can enter mitochondria via the calcium uniporter and inhibit mitochondrial oxidative phosphorylation. It may also inhibit the efflux of Ca(II), which can result in a loss of mitochondrial membrane integrity. Mn(II) has been shown to inhibit mitochondrial aconitase activity to a significant level, altering amino acid metabolism and cellular iron homeostasis. (L228) |
| Signs and Symptoms | Manganese mainly affects the nervous system and may cause behavioral changes and other nervous system effects, which include movements that may become slow and clumsy. This combination of symptoms when sufficiently severe is referred to as “manganism”. (L228) |
| Carcinogen Classification | No indication of carcinogenicity to humans (not listed by IARC). |
| Non-Human Toxicity Excerpts | PERMANGANATE ... OXIDIZES GASTRIC MUCOSAL CELLS. /PERMANGANATE/MOST BACTERIA ARE KILLED WITHIN 1 HR BY PERMANGANATES IN DILUTION OF 1:10,000, BUT SOME MICROORGANISMS SURVIVE EXPOSURE TO MUCH HIGHER CONCN. GERMICIDAL EFFICIENCY ... IS GREATLY REDUCED IN PRESENCE OF ORG MATTER. /PERMANGANATES/ |
| Antidote and Emergency Treatment | Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . /Manganese and related compounds/Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in severe respiratory distress. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors for hypotension with a normal fluid volume. Watch for signs of fluid overload ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Manganese and related compounds/ |
| 州飲料水ガイドライン | (MN) MINNESOTA 300 ug/L /Manganese/ |
| 輸送番号（UN） | UN 1456 |
| 危険等級 | 5.1 |
| 包装等級 | II |
| 有害物質データ | 10118-76-0(Hazardous Substances Data) |
用途
使用
Antiseptic, disinfectant, deodorizer; with CaF2 as binder for welding electrode coatings and fluxes.
一般的な説明
Purple crystalline solid. CALCIUM PERMANGANATE is used as a disinfectant and deodorizer, in water purification, and for many other uses.
製法・合成法
純化方法
Crystallise it from water (3.3mL/g) by partial evaporation in a desiccator. It is deliquescent. Note that it loses oxygen more readily than the potassium salt. It is an oxidising agent.