基本情報
- CAS
12168-85-3- 標準SMILES
[Ca+2].[Ca+2].[O-][Si]([O-])([O-])[O-].[O]=[Ca]- InChIKey
BCAARMUWIRURQS-UHFFFAOYSA-N- 分子式
- Ca3O5Si
- 平均分子量
- 228.32 g/mol
- 単同位体質量
- 227.8392722
概要
might be used as injectable bioactive cement
名称と識別子
- 優先名称
- Tricalcium silicate
- IUPAC
- dicalcium;oxocalcium;silicate
- 現地名
- ケイ酸三カルシウム
- 英語名
- tricalcium silicon pentaoxide
- 分子式
- Ca3H4O5Si-8
- 分子量
- 232.34826
名称と別名
名称をさらに表示
データベース識別子
- CAS
12168-85-3- PubChem CID
- 25523
- DTXSID
DTXSID6049804- EC Number
- 235-336-9
物性
構造計算による物性
- 極性表面積
- 109 Ų
- 水素結合供与体数
- 0
- 水素結合受容体数
- 5
- 回転可能結合数
- 0
- 重原子数
- 9
- 形式電荷
- 0
- 複雑度
- 21.1
実験および物理化学的性質
Physical Description
Large Crystals; CBI; Dry Powder; Other Solid
Colorless solid; [HSDB]
Other Experimental Properties
Hydrates and hardens rapidly
Hardening does not require air, and will occur under water
物理化学的性質
- 融点
- 2150 ℃ · 2150℃ [CRC10]
- 比重(密度)
- 3.14 g/cm3 · 3.14 g/cm3
- 色
- refractory solid
- InChI
- InChI=1S/3Ca.5O.H4Si.4H/h;;;;;;;;1H4;;;;/q;;+2;5*-2;;;;;
- InChIKey
- CEVVLONEMFEQGL-UHFFFAOYSA-N
- SMILES
- [Ca+2].[Ca].[Ca].[SiH4].[O-2].[O-2].[O-2].[O-2].[O-2]
- LogP
- 0.651 · 0.651 (est)
- EPAの化学物質情報
- Tricalcium silicate (12168-85-3)
化学的性質
化学的特性refrac solid [CRC10]
安全と法規制
GHS分類
GHS Classification
This chemical does not meet GHS hazard criteria for 4.8% (1 of 21) of reports.
Danger
H315 (95.2%): Causes skin irritation [Warning Skin corrosion/irritation]
P264, P264+P265, P280, P302+P352, P305+P354+P338, P317, P321, P332+P317, and P362+P364 (click each P-code to see the statement)
Aggregated GHS information provided per 21 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
危険有害性情報
Regulatory Information
Chemical: Calcium oxide silicate (Ca3O(SiO4))
Calcium oxide silicate (Ca3O(SiO4)) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Calcium oxide silicate (Ca3O(SiO4)) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Tricalcium silicate: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
FDA Requirements
Tricalcium silicate used as an anticaking agent, tolerance 2%, is generally recognized as safe when used in table salt in accordance with good manufacturing practice.
Tricalcium silicate used as an anticaking agent, tolerance 2%, is generally recognized as safe when used in table salt in accordance with good manufacturing or feeding practice.
安全と保護具
Disposal Methods
SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal and plant life; and conformance with environmental and public health regulations.
毒性情報
Probable Routes of Human Exposure
According to the 2006 TSCA Inventory Update Report, the number of persons reasonably likely to be exposed in the industrial manufacturing, processing, and use of tricalcium silicate is 1,000 or greater; the data may be greatly underestimated(1).
NIOSH (NOES Survey 1981-1983) has statistically estimated that 62,383 workers (433 of these were female) were potentially exposed to tricalcium silicate in the US(1).
Antidote and Emergency Treatment
/SRP:/ Immediate first aid: Remove patient from contact with the material. Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Inorganic Bases/Alkaline Corrosives and Related Compounds/
/SRP:/ Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 6 to 12 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patent can swallow, has a strong gag reflex, and does not drool ... . Do not attempt to neutralize. Cover skin burns with dry sterile dressings after decontamination ... . /Inorganic Bases/Alkaline Corrosives and Related Compounds/
/SRP:/ Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Early intubation, at the first signs of upper airway obstruction, may be necessary. Positive-pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Inorganic Bases/Alkaline Corrosives and Related Compounds/
法規制情報
FDA Requirements
Tricalcium silicate used as an anticaking agent, tolerance 2%, is generally recognized as safe when used in table salt in accordance with good manufacturing practice.
Tricalcium silicate used as an anticaking agent, tolerance 2%, is generally recognized as safe when used in table salt in accordance with good manufacturing or feeding practice.
安全データ
- tsca
- TSCA listed
- 有毒物質データの
- 12168-85-3(Hazardous Substances Data)
化学と産業
用途と製造
Uses
Used as the main hydraulic compound in Portland cement and as an anti-caking agent in foods; [HSDB]
Cement Producing [Category: Industry]
Tricalcium silicate decisively determines the essential properties of cement.
Absorbent for liquids, gases, vapors; in chromatography, road construction; constituent of lime glass, portland cement; reinforcing filler in elastomers and plastics; suspension agent, anti-caking agent; pigment and pigment extender; binder for refractory material /Calcium silicate/
Principal active hydraulic compound in Portland cement; anticaking agent in foods; component of asbestos-cement wallboard.
U.S. Production
2023: 110,000,000,000 - <120,000,000,000 lb
(1972) 7.26X10+13 GRAMS (PORTLAND CEMENT)
(1975) 6.06X10+13 GRAMS (PORTLAND CEMENT)
Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: Calcium oxide silicate. Aggregated National Production Volume: 1 billion pounds and greater.
Methods of Manufacturing
It is formed by the solid-state reaction between calcium oxide and silica and can be produced from pure CaCO3 and SiO2.
Reaction of calcium oxide (lime) with silica to form dicalcium silicate which reacts with residual lime
Formulations/Preparations
... Hydraulic cement in the form of finely divided, gray powder composed of lime, alumina, silica and iron oxide as tetracalcium aluminoferate, ... tricalcium aluminate, ... tricalcium silicate, ... and dicalcium silicate ... Small amounts of magnesia, sodium, potassium, and sulfur are also present. /cement, Portland/
General Manufacturing Information
Oil and Gas Drilling, Extraction, and Support activities
Calcium oxide silicate (Ca3O(SiO4)): ACTIVE
Portland cement consists mainly of tricalcium silicate and dicalcium silicate.
応用分野
解説ケイ酸三カルシウム(五酸化ケイ素三カルシウム):Ca3SiO5(228.32).固体中には独立した四面体型のSiO4とOを含み,酸化物ケイ酸塩とみなされる.セメントクリンカーの40~70% に当たる主成分で,セメント業界ではケイ酸三石灰(alite)とよばれる.
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