基本情報
- CAS
13465-08-2- 標準SMILES
O=[N+]([O-])[O-].[NH3+]O- InChIKey
CRJZNQFRBUFHTE-UHFFFAOYSA-N- 分子式
- H4N2O4
- 平均分子量
- 96.04 g/mol
- 単同位体質量
- 96.01710661
概要
Hydroxylammonium nitrate (HAN) is the salt of hydroxylamine and nitric acid. It is being developed as a potential rocket propellant and is sometimes used in nuclear reprocessing as a plutonium reductant. Nitrite is a toxic compound known to cause methemoglobinemia. (L1137, L1628)
名称と識別子
- 優先名称
- Hydroxylamine, nitrate
- IUPAC
- hydroxyazanium nitrate
- 現地名
- ヒドロキシルアミン·硝酸塩
- 英語名
- Hydroxylamine nitrate
- 分子式
- H4N2O4
- 分子量
- 96.04
名称と別名
hydroxyazanium;nitrateHydroxylamine, nitrateHydroxylamine, nitrate (salt)Hydroxylamine, nitrate (1:1)EINECS 236-691-2EC 236-691-2NS00086997Q424954硝酸ヒドロキシルアンモニウムヒドロキシルアミン·硝酸塩ヒドロキシルアンモニウム硝酸塩硝酸ヒドロキシルアモニウム
名称をさらに表示
硝酸ヒドロキシルアミン硝酸ヒドロキシルアミン（別名：ヒドロキシルアミン?硝酸塩）ヒドロキシルアミン・硝酸塩HANHydroxylamine nitratehydroxyazanium,nitrateHYDROXYLAMMONIUM OXALATEHYDROXYLAMMONIUM NITRATEhydroxylamine,nitrate(salt)Hydroxylamine nitrate solutionHydroxylamine solution nitrateHydroxylammonium nitrate solutionHYDROXYLAMINENITRATE,AQUEOUSSOLUTION
データベース識別子
- CAS
13465-08-2- PubChem CID
- 26045
物性
構造計算による物性
- 極性表面積
- 111 Ų
- 水素結合供与体数
- 2
- 水素結合受容体数
- 4
- 回転可能結合数
- 0
- 重原子数
- 6
- 形式電荷
- 0
- 複雑度
- 20.8
物理化学的性質
- 比重(密度)
- 1.09 g/mL · 1.09 g/mL at 20 °C
- 蒸気圧
- 9.33 hPa · 9.33hPa at 25℃
- 水溶解度
- 587 g/L · 587g/L at 20℃
- LogP
- -3.6 · -3.6
- CAS データベース
- 13465 · 13465-08-2
- EPAの化学物質情報
- Hydroxylamine nitrate (13465-08-2)
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
毒性情報
Treatment
Methemoglobinemia can be treated with supplemental oxygen and methylene blue 1% solution administered intravenously slowly over five minutes followed by IV flush with normal saline. Methylene blue restores the iron in hemoglobin to its normal (reduced) oxygen-carrying state. (L1613)
Health EffectsNitrate and nitrite poisoning causes methemoglobinemia. Nitrites may cause pregnancy complications and developmental effects. They may also be carcinogenic. (L1137)
Exposure RoutesOral (L1137) ; inhalation (L1137)
Toxicity Summary
Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as methemoglobinemia, and is characterized by tissue hypoxia, as methemoglobin cannot bind oxygen. (A2450, L1613)
Signs and Symptoms
Nitrate and nitrite poisoning causes methemoglobinemia. Symptoms include cyanosis, cardiac dysrhythmias and circulatory failure, and progressive central nervous system (CNS) effects. CNS effects can range from mild dizziness and lethargy to coma and convulsions. (L1137)
Carcinogen ClassificationIngested nitrate or nitrite under conditions that result in endogenous nitrosation is probably carcinogenic to humans (Group 2A). (L135)
安全データ
- wgk
- 3
- tsca
- TSCA listed
- ridadr
- 1759
- risk_code
- 1-22-36/37/38-43-48/22-34-20/21/22-50
- hazard_code
- Xn,C,Xi,N
- safety_code
- 26-36/37-45-36/37/39-35-61
- hazard_class
- 8
- packing_group
- III
化学と産業
薬理情報
Metabolism/Metabolites
Intake of some amount of nitrates and nitrites is a normal part of the nitrogen cycle in humans. In vivo conversion of nitrates to nitrites can occur in the gastrointestional tract under the right conditions, significantly enhancing nitrates' toxic potency. The major metabolic pathway for nitrate is conversion to nitrite, and then to ammonia. Nitrites, nitrates, and their metabolites are excreted in the urine. (L1137)
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