ホキシム

Phoxim

HCID 26927CAS 14816-18-3
部分構造検索類似構造を探す

基本情報

標準SMILES
CCOP(=S)(OCC)ON=C(C#N)c1ccccc1
InChIKey
ATROHALUCMTWTB-UHFFFAOYSA-N
分子式
C12H15N2O3PS
平均分子量
298.3 g/mol
単同位体質量
298.05410052

名称と識別子

優先名称
Phoxim
IUPAC
N-diethoxyphosphinothioyloxybenzenecarboximidoyl cyanide
現地名
ホキシム
英語名
Phoxim
分子式
C12H15N2O3PS
分子量
298.3

名称と別名

PHOXIM14816-18-3BaythionPhoximeSebacil (insecticide)6F5V775VPOBAYER-9053Bay-77488BAY 77488PhoxinDTXSID8034324Phenylglyoxylnitrile oxime O,O-diethyl phosphorothioate
名称をさらに表示
バイチオンチオりん酸O-(α-シアノベンジリデンアミノ)O,O-ジエチルボラトンホキシムO,O-ジエチル-O-(α-シアノベンジリデンアミノ)チオホスフェートキルビスペシャル2-[[(ジエトキシホスフィノチオイル)オキシ]イミノ]-2-フェニルアセトニトリルバレクソンバレキソンチオリン酸－Ｏ，Ｏ－ジエチル－Ｏ－アルファ－シアノベンジリデンアミノホキシム標準品チオリン酸Ｏ，ＯジエチルＯアルファシアノベンジリデンアミノホキシム標準液ホキシム STANDARDホキシム Standard, 100 µg/mL in MeOHFoximb77488VOLATONoms1170Sebacilsra7502Valexon
O,O-Diethyl-alpha-cyanobenzylidineaminooxyphosphonothiateCHEBI:38812Sebacil Pour-onRefChem:863020DTXCID20810007phenylglyoxylonitrile oxime O,O-diethylphosphorothioate238-887-3alpha-(((Diethoxyphosphinothioyl)oxy)imino)benzeneacetonitrile

データベース識別子

CAS
14816-18-3
PubChem CID
26927
DTXSID
DTXSID8034324
ChEMBL
CHEMBL1906626
UNII
6F5V775VPO
EC Number
238-887-3

物性

構造計算による物性

XLogP
4.4
極性表面積
95.9 Ų
水素結合供与体数
0
水素結合受容体数
6
回転可能結合数
7
重原子数
19

実験および物理化学的性質

Collision Cross Section165.7 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID8034324]

物理化学的性質

融点
5.55 °C · 5.55°C
沸点
0.01 · bp0.01 102°
比重(密度)
420 · d420 1.176
蒸気圧
2.1 · 2.1×10-3 Pa (20 °C)
屈折率
20 · nD20 1.5405
貯蔵温度
0 · 0-6°C

化学的性質

化学的特性yellowish oily liquid, Specific gravity: 1.176 (20°C)

安全と法規制

GHS分類

GHS Classification · 6 件

Warning

H302: Harmful if swallowed [Warning Acute toxicity, oral]；H317: May cause an allergic skin reaction [Warning Sensitization, Skin]；H361f ***: Suspected of damaging fertility [Warning Reproductive toxicity]；H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]；H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P203, P261, P264, P270, P272, P273, P280, P301+P317, P302+P352, P318, P321, P330, P333+P317, P362+P364, P391, P405, and P501 (click each P-code to see the statement)

Danger

危険有害性情報

Other Safety Information · 1 件

IMAP assessments - 3,5-Dioxa-6-aza-4-phosphaoct-6-ene-8-nitrile, 4-ethoxy-7-phenyl-, 4-sulfide: Human health tier I assessment；IMAP assessments - 3,5-Dioxa-6-aza-4-phosphaoct-6-ene-8-nitrile, 4-ethoxy-7-phenyl-, 4-sulfide: Environment tier I assessment

Hazard Classes and Categories · 3 件

Acute Tox. 3 (33.6%)；Acute Tox. 4 (66.4%)；Acute Tox. 3 (67.3%)；Skin Sens. 1 (97.3%)；Acute Tox. 2 (34.5%)；Repr. 2 (96.5%)；Aquatic Acute 1 (100%)；Aquatic Chronic 1 (100%)

Reproductive toxicity - category 2；Acute toxicity - category 4；Skin sensitisation - category 1；Hazardous to the aquatic environment (acute) - category 1；Hazardous to the aquatic environment (chronic) - category 1

Repr. 2；Acute Tox. 4 *；Skin Sens. 1；Aquatic Acute 1；Aquatic Chronic 1

毒性情報

Acute Toxicity LinkChemical: PHOXIM

安全データ

wgk
3
rtecs
MD4740000
ridadr
UN 2810
毒性
LD50 orally in mice: >2000 mg/kg (Vinopal, Fukuto)
hs_code
29269090
risk_code
22-50/53-62-43

化学と産業

薬理情報

ATC CodeQP - Antiparasitic products, insecticides and repellents；QP53 - Ectoparasiticides, insecticides and repellents；QP53A - Ectoparasiticides for topical use, incl. insecticides；QP53AF - Organophosphorous compounds；QP53AF01 - Phoxime
MeSH Pharmacological Classification · 2 件

Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.

Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.

用途と製造

Use Classification · 4 件

Veterinary Drug -> INSECTICIDE -> JECFA Functional Classes

Veterinary Drug -> INSECTICIDE -> JECFA Functional Classes

Veterinary Drug -> INSECTICIDE -> JECFA Functional Classes

INSECTICIDES

応用分野 · 2 件

説明Phoxim is a light yellow liquid, Solubility in water is 1.5 mg/L (20 C). It is readily soluble in most organic solvents and slightly in aliphatic hydrocarbons. Log Kow = 3.38. It is relatively slowly hydrolyzed in aqueous media; DT50 (22 C) at pH 4, 7, and 9 is 26.7, 7.2, and 3.1 d, respectively.

使用Phoxim is used to control stored product insect pests in silos and barns. It is also used to control household insects such as ants and other public health pests. Agricultural targets include caterpillars and soil insects in maize, vegetables, cotton and potatoes.

上流・下流製品情報

サプライヤー50 社

国药集团化学试剂有限公司86-21-63210123 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖北万得化工有限公司15377098680 15377098680 · [email protected]
湖北威德利化学试剂有限公司181-6332-1995 18062128043 · [email protected]
盐城通铭生物科技有限公司15195160625 · [email protected]

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