ポリエチレングリコールモノセチルエーテル n≒23

Polyethylene Glycol Cetyl Ether

HCID 2724259
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基本情報

CAS
9004-95-9
標準SMILES
CCCCCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
InChIKey
NLMKTBGFQGKQEV-UHFFFAOYSA-N
分子式
C56H114O21
平均分子量
1,123.5 g/mol
単同位体質量
1,122.78526067

概要

The CIR Expert Panel concluded that the alkyl PEG ethers, listed below, are safe in the present practices of use and concentration described in this safety assessment when formulated to be nonirritating. This assessment is also intended to address future alkyl PEG ether cosmetic ingredients that vary from those ingredients recited herein only by the number of ethylene glycol repeat units...Ceteth-12...

名称と識別子

優先名称
Polyethylene Glycol Cetyl Ether
IUPAC
2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hexadecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
現地名
ポリエチレングリコールモノセチルエーテル n≒23
英語名
Polyethylene Glycol Monocetyl Ether
分子式
C56H114O21
分子量
1123.5

名称と別名

9004-95-9CetocireCETOMACROGOLRomopal OCollone ACLubrol WNikkol BCEthosperse CL20Lipocol C2Ceteth 2Emulgen 210Nikkol BC 15TX
名称をさらに表示
ポリエチレングリコールモノセチルエーテル n≒23ポリエチレングリコールモノセチルエーテル n≒23 [生化学用]POE セチルエ-テルブリジR58αヘキサデシルωヒドロキシポリ（オキシエチレン）セテス－１２セテス－１４セテス－１５セテス－１６セテス－２セテス－２０セテス－２４セテス－２５セテス－３０セテス－４５ポリエチレングリコールモノセチルエーテル (n=約23)ポリエチレングリコールモノセチルエーテル (n=約23) [生化学用]ポリエチレングリコールモノヘキサデシルエーテル (n=約23)ポリオキシエチレンモノセチルエーテル (n=約23)セテス-7CETETH-20BRIJ 5658BRIJ 58bc10BRIJ 52CETETH-7AEO-8BRIJ C10
Nikkol BC 20TXNikkol BC 30Nikkol BC 40Emalex 105Emalex 110Emalex 115Emalex 120Emulgen 2200

データベース識別子

CAS
9004-95-9
PubChem CID
2724259
DTXSID
DTXSID7046708
ChEMBL
CHEMBL2355804
EC Number
500-014-1
Nikkaji
J600.269B

物性

構造計算による物性

XLogP
4.5
極性表面積
205 Ų
水素結合供与体数
1
水素結合受容体数
21
回転可能結合数
74
重原子数
77

実験および物理化学的性質

PolymersOther Classes -> Polyoxyethylenes
Cosmetics · 6 件

Cosmetic ingredients (Ceteth-12) -> CIR (Cosmetic Ingredient Review)

Cosmetic ingredients (Ceteth-14) -> CIR (Cosmetic Ingredient Review)

Cosmetic ingredients (Ceteth-15) -> CIR (Cosmetic Ingredient Review)

Cosmetic ingredients (Ceteth-16) -> CIR (Cosmetic Ingredient Review)

Cosmetic ingredients (Ceteth-24) -> CIR (Cosmetic Ingredient Review)

Cosmetic ingredients (Ceteth-25) -> CIR (Cosmetic Ingredient Review)

Food Contact SubstancesFCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
Physical DescriptionWhite solid; mp = 32-34 deg C; [Sigma-Aldrich MSDS]

物理化学的性質

融点
41 · 41-49 °C
沸点
35.4 · 35.4-39.6 °C
比重(密度)
0.978 g/mL · 0.978 g/mL at 25 °C(lit.)
蒸気圧
0.26 psi · 0.26 psi ( 20 °C)
屈折率
20 · n20/D 1.466(lit.)
闪点
230 °F · >230 °F

化学的性質

化学的特性off-white waxy solid

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 20.6% (173 of 841) of reports.

Warning

H315 (63.9%): Causes skin irritation [Warning Skin corrosion/irritation]

P264, P280, P302+P352, P321, P332+P317, and P362+P364 (click each P-code to see the statement)

Aggregated GHS information provided per 841 reports by companies from 13 notifications to the ECHA C&L Inventory.

Danger

危険有害性情報

Regulatory Information · 4 件

Chemical: Poly(oxy-1,2-ethanediyl), .alpha.-hexadecyl-.omega.-hydroxy-

FRI - indicates a polymeric substance containing no free-radical initiator in its Inventory name but is considered to cover the designated polymer made with any free-radical initiator regardless of the amount used.

Status: Active Update: 21-06-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/25379

Cetomacrogol: Non hazardous

Other Safety InformationIMAP assessments - Ethoxylates of aliphatic alcohols (>C6): Human health tier II assessment
Hazards SummaryCauses tremor, dyspnea, and diarrhea in oral lethal-dose studies of mice; Causes blood serum changes and dermatitis in 4-week intermittent dermal studies of rabbits; [RTECS] May cause irritation; [Sigma-Aldrich MSDS]
EPA Safer ChemicalChemical: Polyethylene glycol monocetyl ether
Hazard Classes and Categories · 2 件

Skin Irrit. 2 (63.9%)

Acute toxicity (ingestion) - category 4

毒性情報

Toxicity Summary · 6 件

The CIR Expert Panel concluded that the alkyl PEG ethers, listed below, are safe in the present practices of use and concentration described in this safety assessment when formulated to be nonirritating. This assessment is also intended to address future alkyl PEG ether cosmetic ingredients that vary from those ingredients recited herein only by the number of ethylene glycol repeat units...Ceteth-12...

Safe for use in cosmetics, with qualifications

The CIR Expert Panel concluded that the alkyl PEG ethers, listed below, are safe in the present practices of use and concentration described in this safety assessment when formulated to be nonirritating. This assessment is also intended to address future alkyl PEG ether cosmetic ingredients that vary from those ingredients recited herein only by the number of ethylene glycol repeat units...Ceteth-14...

Safe for use in cosmetics, with qualifications

The CIR Expert Panel concluded that the alkyl PEG ethers, listed below, are safe in the present practices of use and concentration described in this safety assessment when formulated to be nonirritating. This assessment is also intended to address future alkyl PEG ether cosmetic ingredients that vary from those ingredients recited herein only by the number of ethylene glycol repeat units...Ceteth-15...

Safe for use in cosmetics, with qualifications

安全データ

wgk
3
tsca
TSCA listed
rtecs
TR1581470
毒性
LD50 orally in Rabbit: 2500 mg/kg
hs_code
34021300
risk_code
36/37/38

化学と産業

薬理情報

MeSH Pharmacological Classification · 1 件

Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics.

用途と製造

Uses · 6 件

CIR ingredient: Ceteth-12

CIR ingredient: Ceteth-14

CIR ingredient: Ceteth-15

CIR ingredient: Ceteth-16

CIR ingredient: Ceteth-24

CIR ingredient: Ceteth-25

Household ProductsInformation on 35 consumer products that contain Polyethylene glycol 1000 monocetyl ether in the following categories is provided:
Use Classification · 3 件

EPA Safer Chemical Functional Use Classes -> Surfactants

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Cosmetics -> Emulsifying; Cleansing; Surfactant

General Manufacturing InformationPoly(oxy-1,2-ethanediyl), .alpha.-hexadecyl-.omega.-hydroxy-: ACTIVE
応用分野 · 3 件

用途乳化剤、分散剤、可溶化剤、洗浄剤等であるが、膜タンパクの可溶化剤としても使用される。

使用Polyethylene glycol hexadecyl ether, or Brij 58, has been used in a study to assess properties of gemini-conventional surfactant mixtures and their effects on solubilization of polycyclic aromatic hydrocarbons. It has also been used in a study to investigate RNase-sensitive constraint of bacterial nucleoid structure.

一般的な説明Brij 58 is a nonionic surfactant or detergent for protein extraction and permeabilization of cells. It may be used in the preparation of yeast spheroplasts.

上流・下流製品情報

サプライヤー100 社

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

補足説明

定義本品は、セタノール(*)のポリオキシエチレングリコールエーテルであり、次の化学式で表される。n：平均18参照表示名称：セタノール

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