エリスロシン B
Erythrosine sodium
基本情報
- CAS
16423-68-0- 標準SMILES
O=C([O-])c1ccccc1-c1c2cc(I)c(=O)c(I)c-2oc2c(I)c([O-])c(I)cc12.[Na+].[Na+]- InChIKey
IINNWAYUJNWZRM-UHFFFAOYSA-L- 分子式
- C20H6I4Na2O5
- 平均分子量
- 879.9 g/mol
概要
Erythrosin B is an organic sodium salt that is the disodium salt of 2-(2,4,5,7-tetraiodo-6-oxido-3-oxo-8a,10a-dihydroxanthen-9-yl)benzoic acid. It has a role as a fluorescent dye. It contains an erythrosin(2-).
名称と識別子
- 優先名称
- Erythrosine sodium
- IUPAC
- disodium;2-(2,4,5,7-tetraiodo-3-oxido-6-oxoxanthen-9-yl)benzoate
- 現地名
- エリスロシン B
- 英語名
- ERYTHROSIN B
- 分子式
- C20H8I4O5.2Na
- 分子量
- 881.87
名称と別名
Erythrosine sodiumDTXSID901015598RefChem:1084261DTXCID601233Benzoic acid, 2-(6-hydroxy-2,4,5,7-tetraiodo-3-oxo-3H-xanthen-9-yl)-, disodium saltC.I. Acid Red 51E 127Erythrosine BSFood Red No. 3568-63-8Acid red 51C.I. 45430
名称をさらに表示
エリスロシン B食用 赤色3号ヨードエオシンナトリウム塩エリトロシン赤色3号食用赤色3号エリスロシンピロシンBC.I.アシッドレッド51FDandCレッド32',4',5',7'-テトラヨード-3',6'-ビス(ソジオオキシ)スピロ[イソベンゾフラン-1(3H),9'-[9H]キサンテン]-3-オンジアンチンBエリトロシンBS3',6'-ビス(ソジオオキシ)-2',4',5',7'-テトラヨードスピロ[イソベンゾフラン-1(3H),9'-[9H]キサンテン]-3-オンエリスロシン【色素】テトラヨードフルオレッセインナトリウム塩フードレッドNo.3ヨーデオシンBエリトロシンBC.I.フードレッド14ebsERYTHROSINEERYTHROSINE BTETRAIODOFLUORESCEIN2',4',5',7'-TETRAIODOFLUORESCEIN DISODIUM SALTE127
物性
構造計算による物性
- 極性表面積
- 89.5 Ų
- 水素結合供与体数
- 0
- 水素結合受容体数
- 5
- 回転可能結合数
- 1
- 重原子数
- 31
- 形式電荷
- 0
- 複雑度
- 796
実験および物理化学的性質
CosmeticsHair dyeing
Animal DrugsPharmaceuticals -> UK Veterinary Medicines Directorate List
物理化学的性質
- 融点
- 142 · 142~144℃
- 比重(密度)
- 0.98 · 0.98
- 蒸気圧
- 0 Pa · 0Pa at 25℃
- 闪点
- 285 ℃ · 285℃
- 貯蔵温度
- room temp
- 溶解性
- 100 g/リットル · 100g/リットル
- 酸解離定数(Pka)
- 4.1 · 4.1(at 25℃)
- 外見
- 微粉
- 色
- 濃い赤から茶色
- PH
- 6 · 6-7 (10g/l, H2O, 20℃)
- 水溶解度
- 水に溶ける
- Merck
- 14 · 14,3693
- BRN
- 1443945 · 1443945
- Henry's Law Constant
- 3.9 · 3.9×1013 mol/(m3Pa) at 25℃, Zhang et al. (2010)
- 安定性
- 安定。強力な酸化剤とは相容れない。
- 主な用途
- カラーフィルター、発光ダイオード、ナノセンサー、イメージング材料、インク、塗料、着色泡、洗剤、洗浄剤、化粧品、口腔ケア剤、染毛剤、消毒剤、火傷治療、糖尿病、肥満、癌、ウイルス性疾患、放射線化学療法、光線力学療法
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory.
危険有害性情報
Regulatory InformationErythrosine sodium: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazard Classes and CategoriesAcute Tox. 4 (100%)
毒性情報
Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).
安全データ
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- LM5950000
- ridadr
- UN3077
- 毒性
- LD50 in male, female mice, male, female rats (g/kg): 0.40, 0.32, 0.34, 0.37 i.p.; 6.7, 6.9, 7.4, 6.8 orally (Butterworth); LD50 in mice, rats (mg/kg): 2558, 2891 orally (Yankell)
- hs_code
- 32129000
- risk_code
- 22
- 化審法
- (5)-1503, (5)-1596
- 安衛法
- 57,57-2
- hazard_code
- Xn
- safety_code
化学と産業
用途と製造
Use ClassificationCosmetics -> Hair dyeing
応用分野
用途1. 酸性染料 2. 写真乳剤の色増感剤 3. 分析用試薬 1) 酸塩基指示薬 : pH1.2～2.5でオレンジ色から赤色に変わる。pH3.6以上で暗トウ色のケイ光を発する。 2) 水銀(I)の検出 : 水銀(I)イオンおよび硫酸と反応し、赤色沈殿を作る。
説明FD & C Red No. 3 is principally the disodium salt of the monohydrate of 9(ocarboxyphenyl)-6-hydroxy-2,4,5,7-tetraiodo-3H- xanthen-3-one.The colorant is a brown powder that dissolves in water to give a solution red at neutrality, with a yellow-brown precipitate in acid, and with a red precipitate in base. When dissolved in concentrated sulfuric acid, it yields a brown-yellow solution that evolves iodine and a precipitate of the free acid when heated.FD & C Red No. 3 is used in dietary supplements, confectionery products, dairy products, cherries, jellies, jams, dessert powders, canned fruit and vegetable products, fish products, condiment sauces and bakery goods.1 .
使用Erythrosin B (FD&C Red #3) is a colorant. It is not recommended for use below ph 5.0, being insoluble at ph 3–5 but being stable at ph 7 and 8. It has a solubility in water of 9 g/100 ml at 25°c. It has fair stability to oxidation and poor to fair stability to light, while having good stability in 10% sugar systems. It has exceptional clarity and brilliance, having a bluish pink hue with very good tinctorial strength. It has poor compatibility with food components and is used in candies and confections as well as cherry dyeing. The common name is erythrosine.
一般的な説明Erythrosin B (C.I. 45430)for microscopy Certistain, is a dry dye for microscopy that is often used as a counterstain, vizualising proteins, connective tissues, fibers and keratin in sample material of human origin. Depending on user requirements and personal preferences, it can be used for the preparation of the commonly used aqueous or alcoholic Erythrosin B staining solutions. As the dye belongs to the portfolio of Certistain dyes, it is chemically analyzed according to strict specifications before release (CE marked and IVD product) and a high staining quality, with reliable staining results is guaranteed. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
調製方法
関連反応
2 件
化合物ノート
読み込み中…