フレノシン

解説N-2-hydroxytetracosanoylgalactocerebroside．C48H93NO9(828.27)．フレノシン，セレブロンともいう．構成脂肪酸としてフレノシン酸(セレブロン酸)を有するβ-D-ガラクトセレブロシド．脳，神経組織，脊髄などに含まれる．"針状または小板状結晶．融点212 ℃．[α]D＋4.5°(10％ ピリジン)．熱ジオキサン，ブタノール，クロロホルム，ピリジンに可溶，エタノール，ベンゼンに不溶．種々の2-ヒドロキシ脂肪酸を含むものをフレノシン形，直鎖脂肪酸を含むものをケラシン形として区別されている．森北出版「化学辞典（第2版）

説明Galactosylceramides are glycosphingolipids that contain galactose attached to a ceramide containing an N-acyl hydroxy or non-hydroxy fatty acid. They are metabolic precursors to sulfatides , found primarily in nerve tissues, and are the main glycosphingolipids in the central nervous system. Galactosylceramides are involved in a multitude of cellular processes including cell agglutination, cellular signaling in glycosynapses, cellular development, and activation of T cells. They accumulate in globoid cells in the brain of patients with Krabbe disease, a disorder characterized by a deficiency in galactosylcerebrosidase activity. This product is a mixture of isolated bovine hydroxy galactosylceramides. [Matreya, LLC. Catalog No. 1138]