亜りん酸ジイソプロピル

Diisopropyl phosphite

HCID 3072CAS 1809-20-7

基本情報

標準SMILES
CC(C)O[PH](=O)OC(C)C
InChIKey
BLKXLEPPVDUHBY-UHFFFAOYSA-N
分子式
C6H15O3P
平均分子量
166.16 g/mol
単同位体質量
166.07588133

名称と識別子

優先名称
Diisopropyl phosphite
IUPAC
2-propan-2-yloxyphosphonoyloxypropane
現地名
亜りん酸ジイソプロピル
英語名
Diisopropyl phosphite
分子式
C6H15O3P
分子量
166.16

名称と別名

RefChem:920277217-317-71809-20-7676G4RQ6NDbis(propan-2-yl) phosphonateDiisopropyl hydrogen phosphiteDiisopropyl hydrogen phosphonateDiisopropyl phosphiteDiisopropyl phosphonateDiisopropylphosphonateIsopropyl phosphonateNSC-82344
名称をさらに表示
亜りん酸ジイソプロピルジイソプロピルホスホナートホスホン酸ジイソプロピルホスホン酸ビス(1-メチルエチル)ジイソプロピル=ホスホナート亜りん酸水素ジイソプロピルDiisopropylphosphine oxide3P-230(iPrO)2P(O)HO,O-DiisopropyLisopropylphosphonateDI-I-PROPYLPHOSPHITEDiisopropyl phosphit
O,O-diisopropyl phosphitePhosphonic acid, bis(1-methylethyl) esterPhosphonic acid, diisopropyl ester

データベース識別子

CAS
1809-20-7
PubChem CID
3072
DTXSID
DTXSID7061988
EC Number
217-317-7

物性

構造計算による物性

XLogP
0.4
極性表面積
35.5 Ų
水素結合供与体数
0
水素結合受容体数
3
回転可能結合数
4
重原子数
10

実験および物理化学的性質

Vapor Pressure0.54 [mmHg]
Physical DescriptionLiquid; [Alfa Aesar MSDS]

物理化学的性質

沸点
71 °C · 71 °C (8 mmHg)
比重(密度)
0.997 · 0.997
屈折率
1.4065 · 1.4065-1.4085
闪点
69 °C · 69°C
貯蔵温度
Inert atmosphere,Room Temperature
溶解性
クロロホルム(少量)、メタノール(少量)

化学的性質

化学的特性clear colourless liquid, corrosive, soluble in organic solvents such as ethanol.

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 78.2% (43 of 55) of all reports.

Warning

H302 (20%): Harmful if swallowed [Warning Acute toxicity, oral];H315 (18.2%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (20%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (16.4%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 55 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 43 of 55 reports by companies.;There are 9 notifications provided by 12 of 55 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory Information · 2 件

Chemical: Phosphonic acid, bis(1-methylethyl) ester

Phosphonic acid, bis(1-methylethyl) ester: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazards Summary · 1 件

Causes convulsions and lung changes in inhalation lethal-concentration studies of rats, mice, and guinea pigs; [RTECS] A skin and strong eye irritant; Harmful by inhalation; Toxic by ingestion; [Alfa Aesar MSDS] See Dimethyl hydrogen phosphite.

Hazard Classes and CategoriesAcute Tox. 4 (20%);Skin Irrit. 2 (18.2%);Eye Irrit. 2A (20%);STOT SE 3 (16.4%)

毒性情報

Adverse EffectsNeurotoxin - Other CNS neurotoxin
Toxicity DataLC50 (rat) = 9,600 mg/m3

法規制情報

Regulatory Information · 2 件

Chemical: Phosphonic acid, bis(1-methylethyl) ester

Phosphonic acid, bis(1-methylethyl) ester: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

安全データ

tsca
TSCA listed
rtecs
SZ7660000
ridadr
3265
毒性
guinea pig,LC50,inhalation,9010mg/m3 (9010mg/m3),LUNGS, THORAX, OR RESPIRATION: OTHER CHANGESGASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDSBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD,Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 29(11), Pg. 51, 1985.
hs_code
29209085
risk_code
36/37/38-22

化学と産業

用途と製造

General Manufacturing InformationPhosphonic acid, bis(1-methylethyl) ester: ACTIVE
調製方法 · 1 件

製造方法Diisopropyl phosphite is prepared by directly reacting isopropanol with phosphorus trichloride.3(CH3)2CHOH+PCl3→[(CH3)2CHO]2POH+2HCl↑+(CH3)2CHClAt a ratio of 3:1 (mol), continuously feed 215kg/h of isopropanol and 150kg/h of phosphorus trichloride. When mixed, this results in a violent reaction that generates hydrogen chloride gas. This gas is quickly removed from the mixing pot using vacuum mercury. The crude ester produced is then heated in a falling film type spinner deacidification device and further deacidified. The resulting product is then cooled to below 40°C and obtained with a content of 92%-95% and a yield of 95%~98%.

サプライヤー50 社

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
南京一化生物科技有限公司13429882898; 13429882898
Baoji Guokang Healthchem co.,ltd+8615604608665 15604608665 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]

関連反応

41 件

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