酢酸プレザチド銅

copper;acetic acid;(2S)-6-amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid

HCID 3086626

基本情報

CAS
130120-57-9
標準SMILES
CC(=O)O.NCCCC[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CN)C(=O)O.[Cu+2]
InChIKey
PBAQNGMOINVZLP-ULEGLUPFSA-N
分子式
C16H28CuN6O6+2
平均分子量
463.98 g/mol
単同位体質量
463.13553296

名称と識別子

優先名称
copper;acetic acid;(2S)-6-amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid
IUPAC
copper;acetic acid;(2S)-6-amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid
現地名
酢酸プレザチド銅
英語名
Prezatide copper acetate
分子式
C32H54CuN12O12
分子量
862.39

名称と別名

copper;acetic acid;(2S)-6-amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acidSCHEMBL29360257PBAQNGMOINVZLP-ULEGLUPFSA-N酢酸プレザチド銅酢酸ビス(トリペプチド-1)銅BIS(TRIPEPTIDE-1) COPPER ACETATEprezatide copperGHK-Cu(Prezatide Copper Acetate)copper,acetic acid,(2S)-6-amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acidGHKCu.ACOHGHK-Cu (2:1)GHK-Cu, >=98%
名称をさらに表示
Prezatide copper acetateCopper Tripeptide-3 (AHK-Cu)Copper Tripeptide-1(2:1,HOAc)

データベース識別子

CAS
130120-57-9
PubChem CID
3086626
DTXSID
DTXSID00156359

物性

構造計算による物性

極性表面積
214 Ų
水素結合供与体数
7
水素結合受容体数
9
回転可能結合数
11
重原子数
29

物理化学的性質

化粧品成分の機能
スキンコンディショニング
InChIKey
VJKXESGORYEAGC-UHFFFAOYSA-K
SMILES
C(=O)(O)C.C(C1CC2=CNC=N2[Cu+2]2(N3C=NC(CC(NC(=O)CN)C(=O)NC(C(=O)[O-])CCCCN)=C3)NCC(=O)[N-]12)(=O)NC(C(=O)[O-])CCCCN.[H+]
LogP
-2.241 · -2.241 (est)

安全と法規制

安全データ

注意喚起語
警告
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード H226

化学と産業

応用分野 · 3 件

説明Iamin gel was launched in the US for the care of chronic and acute wounds. It can be prepared by combining the tripeptide GHK and copper (Ⅱ) acetate. There are several species present in equilibrium but the biscomplex is the dominant compound at neutral pH. The GHK sequence is found in only eight human proteins and is an endogenous growth factor that stimulates collagen synthesis and angiogenesis. This is part of the explanation for its wound healing and tissue repair ability. It can significantly delay fibroblast activation, is a growth factor for hepatocyctes, neurons, thyroid follicular cells and is a chemoattractant for monocytes, macrophages, mast cells and capillary endothelial cells. Copper is also known to have an effect on lysyl oxidase which is a key enzyme involved in collagen formation.

使用Prezatide is used for skin care, and has the potential to treat chronic obstructive pulmonary disease and metastatic colon cancer. Prezatide copper acetate is used in personal skin care products with anti-inflammatory and anti-allergic effects, such as essence lotion, cream, facial mask and sunscreen, etc

使用anti-wrikle

サプライヤー100 社

湖北威德利化学试剂有限公司181-6332-1995 18062128043 · [email protected]
Shochem(Shanghai) Co.,Ltd86-21-50800795 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]

補足説明

定義本品は、トリペプチド-1(*)と塩化第二銅(*)との反応生成物の酢酸塩である。参照表示名称:塩化第二銅, トリペプチド-1

関連反応

2 件

化合物ノート

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