4'-アミノアセトアニリド

4-Aminoacetanilide

HCID 31230CAS 122-80-5

基本情報

標準SMILES
CC(=O)Nc1ccc(N)cc1
InChIKey
CHMBIJAOCISYEW-UHFFFAOYSA-N
分子式
C8H10N2O
平均分子量
150.18 g/mol
単同位体質量
150.07931294

概要

P-aminoacetanilide appears as white or slightly reddish solid. (NTP, 1992)

名称と識別子

優先名称
4-Aminoacetanilide
IUPAC
N-(4-aminophenyl)acetamide
現地名
4'-アミノアセトアニリド
英語名
4'-Aminoacetanilide
分子式
C8H10N2O
分子量
150.18

名称と別名

4-AMINOACETANILIDEp-Amino acetanilideDTXSID7024455DTXCID704455RefChem:8579774'-AminoacetanilideN-(4-Aminophenyl)acetamide122-80-5p-Aminoacetanilide4-AcetamidoanilineAcetparaminAcetamide, N-(4-aminophenyl)-
名称をさらに表示
4'-アミノアセトアニリドアセチル-p-フェニレンジアミンフリン88ホウリンAN-アセチル-p-フェニレンジアミン4-(アセチルアミノ)アニリンフォウリンAフリンホウリン88N-アセチル-1,4-フェニレンジアミンp-アセチルアミノアニリンp-アミノアセトアニリドN-(4-アミノフェニル)アセトアミド4-アセチルアミノアニリンC.I.オキシデーションベース19アセトパラミンN-アセチルベンゼン-1,4-ジアミンpアミノアセトアニリド4′-アミノアセトアニリド4-アセトアミドアニリンPARA AMINO ACETANILIDEN-(2-Aminophenyl)acetamide4’-aminoacetanilidc.i.76005fourrineaC.I. 76005
Fourrine Ap-AcetamidoanilineN-Acetyl-p-phenylenediamineAcetyl-p-phenylenediaminep-Acetoaminoaniline4-(Acetylamino)anilineFourrine 88Acetanilide, 4'-amino-

データベース識別子

CAS
122-80-5
PubChem CID
31230
DTXSID
DTXSID7024455
ChEMBL
CHEMBL1318876
ChEBI
CHEBI:229632
UNII
IH5OX0I3Z9
EC Number
204-576-6
Nikkaji
J43.352G

物性

構造計算による物性

XLogP
0.1
極性表面積
55.1 Ų
水素結合供与体数
2
水素結合受容体数
2
回転可能結合数
1
重原子数
11

実験および物理化学的性質

Chemical ClassesNitrogen Compounds -> Other Aromatics (Nitrogen)
SpringerMaterials Properties13C nuclear magnetic resonance spectrum
LogP0.08
Solubility1 to 10 mg/mL at 77 °F (NTP, 1992)
Boiling Point513 °F at 760 mmHg (NTP, 1992)
Melting Point329 to 334 °F (NTP, 1992)

物理化学的性質

融点
164 · 164-167 °C(lit.)
沸点
267 °C · 267 °C
比重(密度)
1.1392 · 1.1392 (rough estimate)
屈折率
1.618 · 1.6180 (estimate)
闪点
195 °C · 195°C
貯蔵温度
30 °C · Store below +30°C.

化学的性質

化学的特性PINK TO BROWN FINE CRYSTALLINE POWDER

安全と法規制

GHS分類

GHS Classification · 5 件

This chemical does not meet GHS hazard criteria for 4.5% (8 of 179) of reports.

Danger

H317 (88.3%): May cause an allergic skin reaction [Warning Sensitization, Skin]

P233, P260, P261, P264+P265, P271, P272, P280, P284, P302+P352, P304+P340, P305+P351+P338, P321, P333+P317, P337+P317, P342+P316, P362+P364, P403, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 179 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Regulatory Information · 3 件

Chemical: Acetamide, N-(4-aminophenyl)-

Acetamide, N-(4-aminophenyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Acetamide, N-(4-aminophenyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 22-03-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/23567

Fire HazardsFlash point data are not available for this chemical, but it is probably combustible. (NTP, 1992)
Health HazardsSYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin, eyes and mucous membranes.
Hazards SummaryA moderate eye irritant; [RTECS] May cause skin, eye, and mucous membrane irritation; [NTP] An eye irritant; [Acros Organics MSDS] See p-Chloroacetanilide.
Reactive GroupAmides and Imides
Reactivity Profile · 1 件

Aromatic amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

安全と保護具

Fire FightingFires involving this compound should be controlled using a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1 件

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 件

SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE) · 1 件

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

安全データ

F
8-9-23
wgk
1
tsca
TSCA listed
rtecs
AD8225000
hs_code
29242995
risk_code
36-42/43-20/21/22-R36

化学と産業

用途と製造

UsesUsed to make azo dyes and pharmaceuticals; [Merck Index]
U.S. Production2023: <50,000 lb
General Manufacturing InformationAcetamide, N-(4-aminophenyl)-: ACTIVE
応用分野 · 3 件

用途アミノアゾ化合物およびp-フェニレンジアミン誘導体の出発原料として用いられ、アゾ系その他種々の酸性染料の中間体として広く使われる。

使用Intermediate in the manufacture of azo dyes, pharmaceuticals.

一般的な説明White or slightly reddish solid.

調製方法

純化方法Crystallise the anilide from water. It has an unstable crystalline form with m 141o. It has IR: max (CCl4) 1681cm-1. [Beilstein 13 H 94, 13 I 28, 13 II 50, 13 III 166, 13 IV 137.]

サプライヤー50 社

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
阿诺西(上海)生物技术有限公司400-1107768 15058188853 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]
宁波君龙新材料有限公司0574 88552216 19032109277 · [email protected]

関連反応

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