基本情報
- CAS
34883-43-7- 標準SMILES
Clc1ccc(-c2ccccc2Cl)cc1- InChIKey
UFNIBRDIUNVOMX-UHFFFAOYSA-N- 分子式
- C12H8Cl2
- 平均分子量
- 223.09 g/mol
- 単同位体質量
- 222.0003056
概要
2,4'-dichlorobiphenyl is a dichlorobiphenyl that is chlorobenzene in which the hydrogen at position 2 has been replaced by a 4-chlorophenyl group. It is a dichlorobiphenyl and a member of monochlorobenzenes.
名称と識別子
- 優先名称
- 2,4'-Dichlorobiphenyl
- IUPAC
- 1-chloro-2-(4-chlorophenyl)benzene
- 現地名
- 2,4'-ジクロロ[1,1'-ビフェニル]
- 英語名
- 2,4'-Dichlorobiphenyl
- 分子式
- C12H8Cl2
- 分子量
- 223.1
名称と別名
2,4'-DICHLOROBIPHENYL34883-43-72,4'-Dichloro-1,1'-biphenylPCB 81,1'-Biphenyl, 2,4'-dichloro-DTXSID0022511TTP086070WCHEBI:342321-chloro-4-(2-chlorophenyl)benzeneRefChem:53554681-934-1DTXCID902511
名称をさらに表示
2,4'-ジクロロ-1,1'-ビフェニル2,4'-ジクロロ[1,1'-ビフェニル]2,4'-ジクロロビフェニル2,4′‐ジクロロビフェニル標準品2,4′‐ジクロロビフェニル標準液2,4'-ジクロロビフェニル (35ΜG/ML イソオクタン溶液)2,4'-DICB (UNLABELED 35 UG/ML IN ISOOCTANE)2,4'-ジクロロビフェニル, 100 µg/mL in Isooctane2,4′-ジクロロ-1,1′-ビフェニル2,4′-ジクロロ[1,1′-ビフェニル]2,4′-ジクロロビフェニルPCB-82,4′-ジクロロビフェニル標準液BZNO 82,4'-CBPCB NO 8C20000800 PCB No. 8Hexanal Impurity 242,4’-dichloro-bipheny2,4’-dichloro-1’-biphenyl
1-chloro-2-(4-chlorophenyl)benzenePCB No. 8Biphenyl, 2,4'-dichloro-CHEMBL1958902,4'-DICHLOROBIPHENYL (IUPAC N.8) (purity)2,4/'-DichlorobiphenylBRN 1946417UNII-TTP086070W
物性
構造計算による物性
- XLogP
- 5.1
- 極性表面積
- 0 Ų
- 水素結合供与体数
- 0
- 水素結合受容体数
- 0
- 回転可能結合数
- 1
- 重原子数
- 14
- 形式電荷
- 0
- 複雑度
- 173
実験および物理化学的性質
SpringerMaterials Properties13C nuclear magnetic resonance spectrum
LogP5.09
Endocrine DisruptorsPotential endocrine disrupting compound
Collision Cross Section141 Ų [M]+ [CCS Type: TIMS, Method: calibration with PAHs]
物理化学的性質
- 融点
- 46 °C · 46°C
- 沸点
- 289.78 °C · 289.78°C (rough estimate)
- 比重(密度)
- 1.249 · 1.2490 (rough estimate)
- 屈折率
- 1.594 · 1.5940 (rough estimate)
- 貯蔵温度
- Sealed in dry,Room Temperature
- 水溶解度
- 0.62 mg/L · 0.62mg/L(25℃)
- BRN
- 1946417 · 1946417
- Henry's Law Constant
- 3.8 · 3.8×10-2 mol/(m3Pa) at 25℃, Li et al. (2003)
- EPAの化学物質情報
- 2 · 2,4'-Dichlorobiphenyl (34883-43-7)
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
Warning
H373 (100%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
P260, P273, P319, P391, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Warning
H350 (100%): May cause cancer [Danger Carcinogenicity]
危険有害性情報
Regulatory InformationSubstance: 2,4-PCB
Hazard Classes and Categories
Carc. 1B (100%)
STOT RE 2 (100%)
安全と保護具
Minimum Risk LevelIntermediate Oral: 0.03 ug/kg/day (L134)
毒性情報
Treatment
There are no specific treatments for PCB poisoning, since it is not usually recognized until after substantial chronic exposure. Only preventing further exposure and treating the observed symptoms can be done. Acute inhalation can be treated by administering oxygen. (L4)
Health Effects
The most common health effects of PCBs are skin conditions such as chloracne and rashes. Chronic PCB exposure has also been shown to cause liver, stomach and kidney, damage, jaundice, edema, anemia, changes in the immune system, behavioral alterations, and impaired reproduction. (L4)
化学と産業
薬理情報
Metabolism/Metabolites
PCBs are absorbed via inhalation, oral, and dermal routes of exposure. They are trasported in the blood, often bound to albumin. Due to their lipophilic nature they tend to accumulate in lipid-rich tissues, such as the liver, adipose, and skin. Metabolism of PCBs is very slow and varies based on the degree and position of chlorination. PCBs are metabolized by the microsomal monooxygenase system catalyzed by cytochrome P-450 enzymes to polar metabolites that can undergo conjugation with glutathione and glucuronic acid. The major metabolites are hydroxylated products which are excreted in the bile and faeces. The slow metabolism of PCBs means they tend to accumulate in body tissues. (L4, T6)
用途と製造
Uses
PCBs were used as coolants and lubricants in transformers, capacitors, and other electrical devices (such as fluorescent lights and refridgerators) produced before 1977. PCBs may contaminate the air and water near hazardous waste sites. In addition, PCBs bioaccumulate in the environment and may be found in fish, meat, and dairy products. (L4)
応用分野
使用2,4''-Dichlorobiphenyl is a polychlorinated biphenyl (PCB) congeners.
上流・下流製品情報
上流原料
サプライヤー42 社
関連反応
0 件
現在のフィルター条件では反応記録がありません。
化合物ノート
読み込み中…