N-ニトロソアミン

Nitrosamine

HCID 37183CAS 35576-91-1

部分構造検索類似構造を探す

基本情報

標準SMILES: NN=O
InChIKey: XKLJHFLUAHKGGU-UHFFFAOYSA-N
分子式: H2N2O
平均分子量: 46.029 g/mol
単同位体質量: 46.01671269

名称と識別子

優先名称: Nitrosamine
IUPAC: nitrous amide
現地名: N-ニトロソアミン
英語名: Nitrosamine
分子式: H2N2O
分子量: 46.03

名称と別名

Nitrosaminenitrous amideNitrosamide35576-91-1N-NITROSAMINELGB75A6POHNSC-223080DTXSID2074037NSC223080RefChem:166119DTXCID6039053CHEBI:35803

名称をさらに表示

ニトロソアミンニトロキシルアミドヒドロキシジイミドN-ニトロソアミン亜硝酸アミドヒドロキシジアゼンニトロソアミドNitsoamideNitrosoamineNitrosamide (8CI,9CI)35576-91-1---NitrosamineBenserazide Impurity 11 (Nitrosamine)

hydroxydiazeneHYDROXYDIIMIDENITROXYLAMIDEketohydrazineHydroxydiiminediazene-N-oxideNSC 223080UNII-LGB75A6POH

データベース識別子

CAS: 35576-91-1
PubChem CID: 37183
DTXSID: DTXSID2074037
UNII: LGB75A6POH
Nikkaji: J332.210F

物性

構造計算による物性

XLogP: -0.6
極性表面積: 55.5 Å²
水素結合供与体数: 1
水素結合受容体数: 3
回転可能結合数: 0
重原子数: 3
形式電荷: 0
複雑度: 10

物理化学的性質

融点: 62 °C · 62 °C
沸点: 191 · 191-195 °C
比重(密度): 1.53 · 1.53±0.1 g/cm3(Predicted)
酸解離定数(Pka): -4.2 · -4.20±0.70(Predicted)
EPAの化学物質情報: Nitrosamine (35576-91-1)

安全と法規制

危険有害性情報

Hazards Summary · 1 件

The acute toxicity of the dialkylnitrosamines decreases with increasing chain length. [ACGIH] Appreciation of the carcinogenicity of the nitrosamines has led to their characterization in many occupational and environmental circumstances. N-nitrosodimethylamine (NDMA) has caused fatal hepatic necrosis after acute exposure and liver cirrhosis after chronic exposure. [LaDou, p. 507-8]

Reactive GroupNitro, Nitroso, Nitrate, and Nitrite Compounds, Organic

Reactivity AlertsStrong Oxidizing Agent

Reactivity ProfileNitrated organics, such as NITROSAMINES, range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction.

Air and Water ReactionsNo rapid reaction with air. No rapid reaction with water.

毒性情報

Adverse EffectsOccupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

化学と産業

用途と製造

Uses · 3 件

Nitrosamines are produced in foundry, tanning, and rubber manufacturing processes. Nitrosamines are carcinogens in experimental animals. [Hawley] Sources of exposure include cigarette smoking, cured or smoked meat and fish, metalworking fluids, rubber vulcanization, leather tanning, and endogenous nitrosation of drugs in the stomach. [Rom, p. 1229-31]

Metal Preparation and Pouring [Category: Foundry]；Metal Machining [Category: Heat or Machine]；Leather Tanning and Processing [Category: Industry]

Smoking cigarettes [Category: Food & Drugs]

サプライヤー6 社

泰州市众致生物科技有限公司[email protected] 15066129350 · [email protected]

金瓯生物医药（南京）有限公司13000000000 · [email protected]

深圳振强药物研发有限公司+86-0755-66853366 +86-13670046396 · [email protected]

河南誉康卓宁进出口有限公司13393721940 · [email protected]

Shaanxi Didu New Materials Co. Ltd+86-86-17392712779 +86-13289823923 · [email protected]