基本情報
- CAS
35693-99-3- 標準SMILES
Clc1ccc(Cl)c(-c2cc(Cl)ccc2Cl)c1- InChIKey
HCWZEPKLWVAEOV-UHFFFAOYSA-N- 分子式
- C12H6Cl4
- 平均分子量
- 292 g/mol
- 単同位体質量
- 289.922361
概要
2,2',5,5'-tetrachlorobiphenyl is a tetrachlorobiphenyl that is biphenyl in which the hydrogens at the 2 and 5 position of each benzene ring are replaced by chlorines. It is a dichlorobenzene and a tetrachlorobiphenyl.
名称と識別子
- 優先名称
- 2,2',5,5'-Tetrachlorobiphenyl
- IUPAC
- 1,4-dichloro-2-(2,5-dichlorophenyl)benzene
- 現地名
- 2,2',5,5'-テトラクロロビフェニル
- 英語名
- 2,2',5,5'-TETRACHLOROBIPHENYL
- 分子式
- C12H6Cl4
- 分子量
- 291.99
名称と別名
2,2',5,5'-TETRACHLOROBIPHENYL35693-99-3PCB 521,1'-Biphenyl, 2,2',5,5'-tetrachloro-2,5,2',5'-Tetrachlorobiphenyl2,2',5,5'-TCB2,2',5,5'-Tetrachloro-1,1'-biphenyl2,3',5,6'-Tetrachlorobiphenyl1,4-dichloro-2-(2,5-dichlorophenyl)benzeneDTXSID30383051EH557950RCHEBI:34206
名称をさらに表示
2,2',5,5'-テトラクロロビフェニル2,2',5,5'-テトラクロロ-1,1'-ビフェニル2,5,2',5'-テトラクロロビフェニル2,5,2',5'-テトラクロロ-1,1'-ビフェニル2,2',5,5'-テトラクロロ[1,1'-ビフェニル]2,2′,5,5′‐テトラクロロビフェニル標準品2,2′,5,5′‐テトラクロロビフェニル標準液2,2',5,5'-PCB (#52)2,2',5,5'-TETRACB (PCB-52) (13C12, 99%) 40+/-2 UG/ML IN NONANE2,2',5,5'-TETRACB 100 UG/ML IN ISOOCTANEPCB NO 52 溶液2,2',5,5'-テトラクロロビフェニル, 100 µg/mL in Isooctane2,2′,5,5′-テトラクロロ-1,1′-ビフェニル2,2′,5,5′-テトラクロロ[1,1′-ビフェニル]2,2′,5,5′-テトラクロロビフェニル2,5,2′,5′-テトラクロロ-1,1′-ビフェニル2,5,2′,5′-テトラクロロビフェニル
物性
構造計算による物性
- XLogP
- 6.1
- 極性表面積
- 0 Ų
- 水素結合供与体数
- 0
- 水素結合受容体数
- 0
- 回転可能結合数
- 1
- 重原子数
- 16
- 形式電荷
- 0
- 複雑度
- 209
実験および物理化学的性質
PolymersPolychlorinated biphenyl
SpringerMaterials Properties13C nuclear magnetic resonance spectrum
LogP5.81
Endocrine DisruptorsPotential endocrine disrupting compound
Collision Cross Section
151.98 Ų [M]+ [CCS Type: TW; Buffer gas: N2; Ionization: GC-APCI+]
156.2 Ų [M-Cl+O]-
155.8 Ų [M]+ [CCS Type: TIMS, Method: calibration with PAHs]
物理化学的性質
- 融点
- 87 ℃ · 87℃
- 沸点
- 374.95 °C · 374.95°C (rough estimate)
- 比重(密度)
- 1.442 · 1.4420 (rough estimate)
- 屈折率
- 1.612 · 1.6120 (rough estimate)
- 闪点
- 4 °C · 4 °C
- 貯蔵温度
- 2 · 2-8°C
- 溶解性
- Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
- 水溶解度
- 109.5 ug/L · 109.5ug/L(25℃)
- BRN
- 2053828 · 2053828
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
Warning
H373 (100%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
P260, P273, P319, P391, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 60 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
危険有害性情報
Regulatory Information
Hazard Traits - Carcinogenicity; Dermatotoxicity; Developmental Toxicity; Endocrine Toxicity; Hepatotoxicity and Digestive System Toxicity; Immunotoxicity; Neurotoxicity; Reproductive Toxicity
Substance: 2,2',5,5'-tetrachlorobiphenyl
Hazard Classes and CategoriesSTOT RE 2 (100%)
安全と保護具
Minimum Risk LevelIntermediate Oral: 0.03 ug/kg/day (L134)
毒性情報
Treatment
There are no specific treatments for PCB poisoning, since it is not usually recognized until after substantial chronic exposure. Only preventing further exposure and treating the observed symptoms can be done. Acute inhalation can be treated by administering oxygen. (L4)
Health Effects
The most common health effects of PCBs are skin conditions such as chloracne and rashes. Chronic PCB exposure has also been shown to cause liver, stomach and kidney, damage, jaundice, edema, anemia, changes in the immune system, behavioral alterations, and impaired reproduction. (L4)
化学と産業
薬理情報
Metabolism/Metabolites
PCBs are absorbed via inhalation, oral, and dermal routes of exposure. They are trasported in the blood, often bound to albumin. Due to their lipophilic nature they tend to accumulate in lipid-rich tissues, such as the liver, adipose, and skin. Metabolism of PCBs is very slow and varies based on the degree and position of chlorination. PCBs are metabolized by the microsomal monooxygenase system catalyzed by cytochrome P-450 enzymes to polar metabolites that can undergo conjugation with glutathione and glucuronic acid. The major metabolites are hydroxylated products which are excreted in the bile and faeces. The slow metabolism of PCBs means they tend to accumulate in body tissues. (L4, T6)
用途と製造
Uses
PCBs were used as coolants and lubricants in transformers, capacitors, and other electrical devices (such as fluorescent lights and refridgerators) produced before 1977. PCBs may contaminate the air and water near hazardous waste sites. In addition, PCBs bioaccumulate in the environment and may be found in fish, meat, and dairy products. (L4)
上流・下流製品情報
下流製品
サプライヤー49 社
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
盐城通铭生物科技有限公司15195160625 · [email protected]
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