3-モルホリノプロパンスルホン酸ナトリウム
3-モルホリノプロパンスルホン酸ナトリウム · MOPSナトリウム塩 · 3-モルホリノ-1-プロパンスルホン酸ナトリウム · 3-モルホリノプロパン-1-スルホン酸ナトリウム · 3-モルホリノプロパンスルホン酸ナトリウム塩 · MOPS ナトリウム塩 · 3-モルホリノ-1-プロパンスルホナート · 3-(モルホリン-4-イル)プロパン-1-スルホナート
識別子と物理属性
| CAS No. | 117961-20-3 |
|---|---|
| 分子式 | C7H14NNaO4S |
| 平均分子量 | 231.25 g/mol |
| 単同位体質量 | 231.05412338 g/mol |
| SMILES | O=S(=O)([O-])CCCN1CCOCC1.[Na+] |
| InChIKey | MWEMXEWFLIDTSJ-UHFFFAOYSA-M |
| PubChem CID | 3859613 |
| EC No. | 428-420-3 |
| DTXSID | DTXSID3072246 |
| 現地名 | 3-モルホリノプロパンスルホン酸ナトリウム |
化学・物理的性質
| 極性表面積 | 78.1 |
|---|---|
| 水素結合供与体数 | 0 |
| 水素結合受容体数 | 5 |
| 回転可能結合数 | 4 |
| 重原子数 | 14 |
| 形式電荷 | 0 |
| 複雑度 | 233 |
| 融点 | 277-282°C |
| 密度 | 1.41[at 20℃] |
| 貯蔵条件 | room temp |
| 溶解度 | H2O: 1M at20℃、透明、無色水に溶けます (20°C で 523 g/L)。 |
| 外観・状態 | 粉体・固形 |
| 色 | 白い |
| pH | 10.0-12.0 (1M in H2O) |
| pKa（酸解離定数） | 7.2(at 25℃) |
| 由来生物 | synthetic |
| 主な用途 | 診断アッセイの製造 |
| InChI | 1S/C7H15NO4S.Na/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)/q+1/p-1 |
| InChIKey | MWEMXEWFLIDTSJ-UHFFFAOYSA-M |
| SMILES | [Na+].[O-]S(=O)(=O)CCCN1CCOCC1 |
| CAS データベース | 71119-22-7(CAS DataBase Reference) |
| EPAの化学物質情報 | 4-Morpholinepropanesulfonic acid, sodium salt (71119-22-7) |
| Absorption | ≤0.1 at 260 in H2O at 1M≤0.1 at 280 in H2O at 1M |
化学的特性
white powder
安全性と法規制
| GHS 分類 | This chemical does not meet GHS hazard criteria for 4.2% (2 of 48) of reports.WarningH315 (93.8%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 48 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.This chemical does not meet GHS hazard criteria for 100% (11 of 11) of all reports. |
|---|---|
| 規制情報 | PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.REACH registered substance: Sodium 3-morpholin-4-ylpropane-1-sulfonate (EC: 428-420-3)4-Morpholinepropanesulfonic acid, sodium salt: Does not have an individual approval but may be used under an appropriate group standard |
| Hazard Classes and Categories | Skin Irrit. 2 (93.8%)Not Classified |
| F | 10 |
| 水環境危害等級（WGK） | 1 |
| TSCA 収載状態 | TSCA listed |
| 税関コード | 29349097 |
| 危険文句（R） | 36/37/38 |
| 危険表示 | Xi |
| 安全措置（S） | 24/25-36-26 |
| 貯蔵分類 | 13 - Non Combustible Solids |
用途
説明
MOPS sodium salt is a buffering agent used in biochemistry and molecular biology that was selected and described by Good et al. It is a zwitterionic, morpholinic buffer that is useful for a pH range of 6.5 – 7.9 and commonly used for cell culture media, as a running buffer in electrophoresis and for protein purification in chromatography. MOPS lacks the ability to form a complex with most metal ions and is recommended for use as a non-coordinating buffer in solutions with metal ions. MOPS is often used in buffered culture media for bacteria, yeast, and mammalian cells. MOPS is regarded as an excellent buffer for use in separating RNA in agarose gels. It is recommended to sterilize MOPS buffers by filtration rather than with autoclave due to the unknown identity of yellow degradation products that occur after sterilization of MOPS with autoclave. It is suitable for use in the bicinchoninic acid (BCA) assay.MOPS sodium salt can be mixed with MOPS free acid to attain desired pH. Alternatively, MOPS free acid can be titrated with sodium hydroxide to attain desired pH.
使用
MOPS Sodium Salt is a buffering agent used in organic chemistry.