基本情報
- CAS
9002-61-3- 標準SMILES
N[C@@H](CCCC(=O)N[C@@H](CS)C(=O)NCC(=O)O)C(=O)O- InChIKey
XFOOPZIJVVDYHI-BQBZGAKWSA-N- 分子式
- C11H19N3O6S
- 平均分子量
- 321.35 g/mol
- 単同位体質量
- 321.09945651
概要
See also: Human Chorionic Gonadotropin (annotation moved to); Serum Gonadotrophin (annotation moved to).
名称と識別子
- 優先名称
- delta-(L-alpha-Aminoadipoyl)-L-cysteinyl-glycine
- IUPAC
- (2S)-2-amino-6-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-6-oxohexanoic acid
- 現地名
- 胎盤性性腺刺激ホルモン
- 英語名
- Chorionic Gonadotropin
- 分子式
- C17H28
- 分子量
- 232.40422
名称と別名
9002-61-3DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-GLYCINEHCGCHORIONIC GONADOTROPIN HUMANChorionic gonadotrophinCHEMBL1233255XFOOPZIJVVDYHI-BQBZGAKWSA-NMSK10885(2S)-2-amino-6-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-6-oxohexanoic acidQ27461047N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinylglycineヒト絨毛性ゴナドトロピン (5,760 USP UNITS PER PACKAGE)
名称をさらに表示
胎盤性性線刺激ホルモン胎盤性性線刺激ホルモン, ヒト妊婦尿由来絨毛性ゴナドトロピン ヒト胎盤性性腺刺激ホルモンヒト絨毛性性腺刺激ホルモンHUMAN CHORIONIC GONADOTROPINLHAHUMAN CHORIONIC GONADOTROPHINaplpregnylHGGHCG 5000IUchoragonchoriogonadotropin
物性
構造計算による物性
- XLogP
- -4.1
- 極性表面積
- 160 Ų
- 水素結合供与体数
- 6
- 水素結合受容体数
- 8
- 回転可能結合数
- 10
- 重原子数
- 21
- 形式電荷
- 0
- 複雑度
- 403
物理化学的性質
- 貯蔵温度
- 2 · 2-8°C
- 溶解性
- 2 O: · H2O: ソリュブル1ML/バイアル
- 外見
- 凍結乾燥粉末
- 色
- White to off-white
- 由来生物
- human urine
- 水溶解度
- water: soluble
化学的性質
化学的特性White or yellowish-white, amorphous powder.
安全と法規制
GHS分類
GHS Classification
Danger
H317 (20.5%): May cause an allergic skin reaction [Warning Sensitization, Skin]
P203, P233, P260, P261, P264, P270, P271, P272, P280, P284, P302+P352, P304+P340, P317, P318, P319, P321, P333+P317, P342+P316, P362+P364, P403, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 117 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
危険有害性情報
Other Safety InformationIMAP assessments - Gonadotropin, chorionic: Human health tier I assessment
Hazard Classes and CategoriesSkin Sens. 1 (20.5%)
安全データ
- wgk
- 3
- rtecs
- MD6953000
- hs_code
- 2937190000
- risk_code
- 63-62
- hazard_code
- B,Xn
- safety_code
- 22-36-36/37
- Hazard Classifications
- Repr. 2
- ストレージクラス
- 11 - Combustible Solids
- 有毒物質データの
- 9002-61-3(Hazardous Substances Data)
化学と産業
薬理情報
ATC Code
G - Genito urinary system and sex hormones
QG - Genito urinary system and sex hormones
応用分野
使用Chorionic gonadotropin human has been used: to induce oocyte maturation in cultured folliclesalong with pregnant mare serum gonadotropin (PMSG) to induce superovulation in mice as medium component for fetal testes culture to aid steroidogenic responsiveness
一般的な説明Glycoprotein hormone consisting of a 92-amino acid α-chain which is identical to that of LH, FSH, and TSH; and a distinct 149-amino acid β-chain. Produced by chorionic tissue and responsible for maintaining the corpus luteum during early pregnancy. Also produced by trophoblast cell neoplasms, which are marked by elevated free hCG β-chains and hyperglycosylated hCG.
調製方法
CG is produced in the chorion.
上流・下流製品情報
上流原料
関連反応
0 件
現在のフィルター条件では反応記録がありません。
化合物ノート
読み込み中…