Paromomycin Sulfate

HCID 441375

データを補完しています。通常は 1 分以内に完了します

基本情報

CAS
1263-89-4
標準SMILES
NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3N)O[C@@H]2CO)[C@H](N)[C@@H](O)[C@@H]1O.O=S(=O)(O)O
InChIKey
LJRDOKAZOAKLDU-UDXJMMFXSA-N
分子式
C23H47N5O18S
平均分子量
713.7 g/mol
単同位体質量
713.26368084

名称と識別子

優先名称
Paromomycin Sulfate
IUPAC
(2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(2R,3S,4R,5S)-5-[(1R,2R,3S,5R,6S)-3,5-diamino-2-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-hydroxycyclohexyl]oxy-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxyoxane-3,4-diol;sulfuric acid

名称と別名

Paromomycin sulfate1263-89-4GabbromicinaGabbroralHumagelAminosidin sulfateAminosidine sulfateAminosidine sulphateFarminosidinAminoxidinFarmiglucinSinosid
名称をさらに表示
PargonylHumycin sulfateParomomycin sulphateParamicinaParicina845NU6GJPSGabbromycin1600 Antibiotic

データベース識別子

CAS
1263-89-4、7205-49-4
PubChem CID
441375
DTXSID
DTXSID601335979
ChEMBL
CHEMBL2206196
ChEBI
CHEBI:7935
UNII
845NU6GJPS
EC Number
215-031-7、230-575-5

物性

構造計算による物性補完中

極性表面積
430 Ų
水素結合供与体数
15
水素結合受容体数
23
回転可能結合数
9
重原子数
47

安全と法規制

GHS分類

GHS Classification · 3 件

This chemical does not meet GHS hazard criteria for 93% (53 of 57) of all reports.

Not Classified;Reported as not meeting GHS hazard criteria by 53 of 57 companies (only 7% companies provided GHS information). For more detailed information, please visit ECHA C&L website.

Aggregated GHS information provided per 57 reports by companies from 5 notifications to the ECHA C&L Inventory.;Reported as not meeting GHS hazard criteria per 53 of 57 reports by companies.;There are 4 notifications provided by 4 of 57 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory InformationRegulation (EC) No 1831/2003 (amended)
Hazard Classes and CategoriesNot Classified

毒性情報

Drug Induced Liver Injury · 6 件

Drug Induced Liver Injury Rank (DILIrank 2.0)

Paromomycin sulfate

vNo-DILI-concern

0

No match

DOI:10.1016/j.drudis.2016.02.015

Effects During Pregnancy and Lactation · 1 件

◉ Summary of Use during Lactation;No information is available on the clinical use of paromomycin during breastfeeding. Because paromomycin is poorly absorbed orally, it is not likely to reach the bloodstream of the infant or cause any adverse effects in breastfed infants.;◉ Effects in Breastfed Infants;Relevant published information was not found as of the revision date.;◉ Effects on Lactation and Breastmilk;Relevant published information was not found as of the revision date.

法規制情報

Regulatory InformationRegulation (EC) No 1831/2003 (amended)

化学と産業

薬理情報

FDA Pharmacological Classification · 2 件

PAROMOMYCIN SULFATE

Antiprotozoal [EPC]

MeSH Pharmacological Classification · 2 件

Substances that are destructive to protozoans.

Substances that inhibit the growth or reproduction of BACTERIA.

サプライヤー13 社

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
湖北研科时代科技有限公司15780669880 · [email protected]
湖北恒硕化工有限公司027-82830253 13995541600 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
安耐吉化学&3A(安徽泽升科技股份有限公司)400-0056266 · [email protected]

関連反応

2 件

化合物ノート

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