データを補完しています。通常は 1 分以内に完了します
基本情報
- CAS
1263-89-4- 標準SMILES
NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3N)O[C@@H]2CO)[C@H](N)[C@@H](O)[C@@H]1O.O=S(=O)(O)O- InChIKey
LJRDOKAZOAKLDU-UDXJMMFXSA-N- 分子式
- C23H47N5O18S
- 平均分子量
- 713.7 g/mol
- 単同位体質量
- 713.26368084
名称と識別子
- 優先名称
- Paromomycin Sulfate
- IUPAC
- (2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(2R,3S,4R,5S)-5-[(1R,2R,3S,5R,6S)-3,5-diamino-2-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-hydroxycyclohexyl]oxy-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxyoxane-3,4-diol;sulfuric acid
名称と別名
名称をさらに表示
データベース識別子
- CAS
1263-89-4、7205-49-4- PubChem CID
- 441375
- DTXSID
DTXSID601335979- ChEMBL
CHEMBL2206196- ChEBI
CHEBI:7935- UNII
- 845NU6GJPS
- EC Number
- 215-031-7、230-575-5
物性
構造計算による物性補完中
- 極性表面積
- 430 Ų
- 水素結合供与体数
- 15
- 水素結合受容体数
- 23
- 回転可能結合数
- 9
- 重原子数
- 47
- 形式電荷
- 0
- 複雑度
- 952
安全と法規制
GHS分類
GHS Classification
This chemical does not meet GHS hazard criteria for 93% (53 of 57) of all reports.
Not Classified;Reported as not meeting GHS hazard criteria by 53 of 57 companies (only 7% companies provided GHS information). For more detailed information, please visit ECHA C&L website.
Aggregated GHS information provided per 57 reports by companies from 5 notifications to the ECHA C&L Inventory.;Reported as not meeting GHS hazard criteria per 53 of 57 reports by companies.;There are 4 notifications provided by 4 of 57 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
危険有害性情報
毒性情報
Drug Induced Liver Injury
Drug Induced Liver Injury Rank (DILIrank 2.0)
Paromomycin sulfate
vNo-DILI-concern
0
No match
DOI:10.1016/j.drudis.2016.02.015
Effects During Pregnancy and Lactation
◉ Summary of Use during Lactation;No information is available on the clinical use of paromomycin during breastfeeding. Because paromomycin is poorly absorbed orally, it is not likely to reach the bloodstream of the infant or cause any adverse effects in breastfed infants.;◉ Effects in Breastfed Infants;Relevant published information was not found as of the revision date.;◉ Effects on Lactation and Breastmilk;Relevant published information was not found as of the revision date.
法規制情報
化学と産業
薬理情報
FDA Pharmacological Classification
PAROMOMYCIN SULFATE
Antiprotozoal [EPC]
MeSH Pharmacological Classification
Substances that are destructive to protozoans.
Substances that inhibit the growth or reproduction of BACTERIA.
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