ステビオシド

Stevioside

HCID 442089CAS 57817-89-7
部分構造検索類似構造を探す

基本情報

標準SMILES
C=C1C[C@@]23CC[C@H]4[C@@](C)(CCC[C@@]4(C)C(=O)O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@H]2CC[C@]1(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C3
InChIKey
UEDUENGHJMELGK-HYDKPPNVSA-N
分子式
C38H60O18
平均分子量
804.9 g/mol
単同位体質量
804.37796506

名称と識別子

優先名称
Stevioside
IUPAC
[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,4S,5R,9S,10R,13S)-13-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylate
現地名
ステビオシド
英語名
Stevioside
分子式
C38H60O18
分子量
804.88

名称と別名

SteviosideSteviosin57817-89-70YON5MXJ9PCHEBI:9271INS NO.960DTXSID7021281FEMA NO. 4763INS-960E-960((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl) (1R,4S,5R,9S,10R,13S)-13-((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxyoxan-2-yl)oxy-5,9-dimethyl-14-methylidenetetracyclo(11.2.1.01,10.04,9)hexadecane-5-carboxylate(4bS,8aS)-1-hydroxy-2-isopropyl-4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthrene-3,4-dione
名称をさらに表示
ステビオサイド標準品ステビオシドステビオサイドステビオシド標準品ステビオシド 水和物13-[(2-O-β-D-グルコピラノシル-β-D-グルコピラノシル)オキシ]カウラ-16-エン-18-酸β-D-グルコピラノシル(4R)-13-[(2-O-β-D-グルコピラノシル-β-D-グルコピラノシル)オキシ]カウラ-16-エン-18-酸β-D-グルコピラノシル(2S,3R,4S,5S,6R)-3,4,5-トリヒドロキシ-6-(ヒドロキシメチル)オキサン-2-イル (1R,4S,5R,9S,10R,13S)-13-{[(2S,3R,4S,5S,6R)-4,5-ジヒドロキシ-6-(ヒドロキシメチル)-3-{[(2S,3R,4S,5S,6R)-3,4,5-トリヒドロキシ-6-(ヒドロキシメチル)オキサン-2-イル]オキシ}オキサン-2-イル]オキシ}-5,9-ジメチル-14-メチリデンテトラシクロ[11.2.1.01,10.04,9]ヘキサデカン-5-カルボキシラートステビオシン13-(2-O-β-D-グルコピラノシル-β-D-グルコピラノシルオキシ)カウラ-16-エン-18-酸β-D-グルコピラノシルGLUCOSYL STEVIOL GLYCOSIDESSTEVIA LEAF EXTRACTSteviosidesStevia 95% (froM Stevia rebaudiana) anhydrousStevioside (90%)Stevioside powderStevioside - min 80%
[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,4S,5R,9S,10R,13S)-13-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylateRefChem:51134DTXCID301281260-975-5RebaudinDiterpene glycosideSTEVIBIOSIDE.ALPHA.-G-SWEET

データベース識別子

CAS
57817-89-7
PubChem CID
442089
DTXSID
DTXSID7021281
ChEMBL
CHEMBL444122
ChEBI
CHEBI:9271
UNII
0YON5MXJ9P
EC Number
260-975-5
Nikkaji
J27.441K

物性

構造計算による物性

XLogP
-1.2
極性表面積
295 Ų
水素結合供与体数
11
水素結合受容体数
18
回転可能結合数
10
重原子数
56

実験および物理化学的性質

Solubility1.25 mg/mL
Melting Point238 - 239 °C
Physical DescriptionSolid
Collision Cross Section269.64 Ų [M+H]+ [CCS Type: TW]

物理化学的性質

融点
198 °C · 198°C
沸点
963.3 · 963.3±65.0 °C(Predicted)
比旋光度
25 · D25 -39.3° (c = 5.7 in H2O)
比重(密度)
1.53 · 1.53±0.1 g/cm3(Predicted)
屈折率
-39.3 ° · -39.3 ° (C=6, H2O)
FEMA
4728 · 4728 | GLUCOSYL STEVIOL GLYCOSIDES

化学的性質

化学的特性White powder

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 85.7% (6 of 7) of all reports.

Warning

H315 (14.3%): Causes skin irritation [Warning Skin corrosion/irritation]；H317 (14.3%): May cause an allergic skin reaction [Warning Sensitization, Skin]；H319 (14.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P261, P264, P264+P265, P272, P280, P302+P352, P305+P351+P338, P321, P332+P317, P333+P317, P337+P317, P362+P364, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 7 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 6 of 7 reports by companies.；There is 1 notification provided by 1 of 7 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory Information · 2 件

Chemical: Kaur-16-en-18-oic acid, 13-[(2-O-.beta.-D-glucopyranosyl-.beta.-D-glucopyranosyl)oxy]-, .beta.-D-glucopyranosyl ester, (4.alpha.)-

Kaur-16-en-18-oic acid, 13-(2-O-.beta.-D-glucopyranosyl-.beta.-D-glucopyranosyl)oxy-, .beta.-D-glucopyranosyl ester, (4.alpha.)-: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesSkin Irrit. 2 (14.3%)；Skin Sens. 1 (14.3%)；Eye Irrit. 2 (14.3%)

法規制情報

Regulatory Information · 2 件

Chemical: Kaur-16-en-18-oic acid, 13-[(2-O-.beta.-D-glucopyranosyl-.beta.-D-glucopyranosyl)oxy]-, .beta.-D-glucopyranosyl ester, (4.alpha.)-

Kaur-16-en-18-oic acid, 13-(2-O-.beta.-D-glucopyranosyl-.beta.-D-glucopyranosyl)oxy-, .beta.-D-glucopyranosyl ester, (4.alpha.)-: Does not have an individual approval but may be used under an appropriate group standard

安全データ

wgk
3
rtecs
NZ8175000
hs_code
29389090
safety_code
22-24/25
ストレージクラス
11 - Combustible Solids

化学と産業

薬理情報

MeSH Pharmacological ClassificationSubstances that sweeten food, beverages, medications, etc., such as sugar, saccharine or other low-calorie synthetic products. (From Random House Unabridged Dictionary, 2d ed)
Cellular LocationsCytoplasm；Extracellular；Membrane

用途と製造

Use Classification · 2 件

Food Additives -> SWEETENER -> JECFA Functional Classes

Cosmetics -> Masking; Oral care

応用分野 · 3 件

解説ステビオシド，ステビオシドは吸湿性の結晶．融点198 ℃．[α]25D－39.3°(水)．800 mL の水に1 g 溶けるが，有機溶媒に難溶．食品の甘味料として使用される．ステビオールC20H30O3(318.46)は針状結晶．融点215 ℃．[α]D－94.7°．植物生長促進作用をもっている．森北出版「化学辞典（第2版）

天然物の起源Stevioside is a naturally occurring sweetener (～200 times sweeter than sucrose) extracted from a South American plant, Stevia rebaudiana Bertoni. The dried leaves, the water extract of leaves, and the refined chemical ingredients, eg, and Rebaudioside A (～300 times sweeter than sucrose), can all be used as sweetening agents. These are collectively referred to as stevia. Discovered in Paraguay and Brazil, the plant was identified in the early 1970s as a plant of high economical value and transported to Japan for cultivation, where the commercialization of stevia leaves extract as a natural sweetener became a success. Today Stevia plant is cultivated primarily in China.

来歴Because no food additive petition has been presented to the FDA, stevioside and related materials cannot be used in the United States as food ingredients. An import alert against stevia was issued by the FDA in 1991. In 1995, however, the FDA revised this import alert to allow the importation and use of stevia as a dietary supplement, but not as a sweetener or an ingredient for foods. In 2004, JECFA (Joint Expert Committee of Food Additives) issued a preliminary ADI (Allowed Daily Intake) of 2-mg/kg body weight (based on steviol) for stevia extract. This action may impact favorably on worldwide regulatory approval. As consumer’s demand on naturally sweetened products increases, interest in Stevia, and naturally occurring potent sweeteners in general, is expected to grow. A comprehensive review of stevia is available [Kinghorn, 2002].

上流・下流製品情報

サプライヤー50 社

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]

補足説明

定義本品は、ステビア Stevia rebaudiana から分離される炭水化物である。[Eupatorium rebaudianum]

関連反応

2 件
反応記録を作成

関連ノート

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