6-ブロモ-2-クロロ-8-シクロペンチル-5-メチルピリド[2,3-D]ピリミジン-7(8H)-オン

説明6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one is a pharmaceutical intermediate that can be used to synthesize Palbociclib, an inhibitor of cyclin-dependent kinases (CDKs) 4 and 6 for the treatment of breast cancer.

一般的な説明6-bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one is a key intermediate in the synthesis of Ibrance[1]. The structural feature of this compound lies in its incorporation of two functional groups—bromine and chlorine—which heighten its reactivity during synthesis. Furthermore, it may also be employed in the synthesis of palbociclib and its salt derivatives[2].