化工社化工社 化学情報印刷レポート · 研究参考用
オキシドパミン
オキシドパミン · ヒドロキシドーパミン · 5-(2-アミノエチル)-1,2,4-ベンゼントリオール · 6-ヒドロキシドーパミン · 2,4,5-トリヒドロキシフェネチルアミン · 5-(2-アミノエチル)ベンゼン-1,2,4-トリオール · 6-ヒドロキシドパミン · 2-(2,4,5-トリヒドロキシフェニル)エタンアミン
識別子と物理属性
| CAS No. | 1199-18-4 |
|---|---|
| 分子式 | C8H11NO3 |
| 平均分子量 | 169.18 g/mol |
| 単同位体質量 | 169.07389321 g/mol |
| SMILES | NCCc1cc(O)c(O)cc1O |
| InChIKey | DIVDFFZHCJEHGG-UHFFFAOYSA-N |
| PubChem CID | 4624 |
| ChEMBL | CHEMBL337702 |
| ChEBI | CHEBI:78741 |
| EC No. | 214-842-3 |
| DTXSID | DTXSID0036768 |
| 現地名 | オキシドパミン |
化学・物理的性質
| XLogP | 0.2 |
|---|---|
| 極性表面積 | 86.7 |
| 水素結合供与体数 | 4 |
| 水素結合受容体数 | 4 |
| 回転可能結合数 | 2 |
| 重原子数 | 12 |
| 形式電荷 | 0 |
| 複雑度 | 142 |
| 融点 | 232 °C |
| Physical Description | 6-hydroxydopamine is a solid. Used as a pharmacological agent. |
| Collision Cross Section | 143 Ų [M+H]+ [CCS Type: DTMethod: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]143.2 Ų [M+H]+ |
| 沸点 | 298.46°C (rough estimate) |
| 密度 | 1.2435 (rough estimate) |
| 屈折率 | 1.5100 (estimate) |
| EPAの化学物質情報 | 6-Hydroxydopamine (1199-18-4) |
安全性と法規制
| 輸送ラベル（DOT） | Poison |
|---|---|
| 火災危険 | Flash point data for this chemical are not available. It is probably combustible. (NTP, 1992) |
| 健康有害性 | SYMPTOMS: Symptoms of exposure to this chemical may include a prolonged decomposition in catecholamine content of the heart (shown to be due to the destruction of sympathetic nerve endings). (NTP, 1992) |
| 反応性グループ | Amines, Phosphines, and Pyridines |
| Reactivity Profile | Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. |
| Air and Water Reactions | No rapid reaction with air. No rapid reaction with water. |
| 消火 | Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992) |
| 応急処置 | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
| 非火災時の漏出対応 | STORAGE PRECAUTIONS: You should store this material in a refrigerator. (NTP, 1992) |
| Isolation and Evacuation | Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: |
| Personal Protective Equipment (PPE) | RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992) |
用途
使用
Adrenergic (ophthalmic).
一般的な説明
Solid. Used as a pharmacological agent.