化工社化工社 化学情報印刷レポート · 研究参考用
HCID 4742004作成日：2026年10月26日
1-シクロプロピルピペラジン
1-シクロプロピルピペラジン · Cyclopropyl piperazine · N-cyclopropylpiperazine · 1-Cyclopropylpiperazine · Piperazine,1-cyclopropyl- · 1-Cyclopropylpiperazine >(Piperazin-1-yl)cyclopropane · 1-(Cyclopropyl Phenyl)Piperazine · 1-Cyclopropylpiperazine - [C14363]
https://huagongshe.com/ja/chemical/4742004
識別子と物理属性
| CAS No. | 20327-23-5 |
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| 分子式 | C7H14N2 |
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| 平均分子量 | 126.2 g/mol |
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| 単同位体質量 | 126.11569845 g/mol |
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| SMILES | C1CN(C2CC2)CCN1 |
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| InChIKey | HNZJIWIXRPBFAN-UHFFFAOYSA-N |
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| PubChem CID | 4742004 |
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| EC No. | 807-993-7 |
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| DTXSID | DTXSID20406303 |
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| 現地名 | 1-シクロプロピルピペラジン |
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化学・物理的性質
| XLogP | 0.2 |
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| 極性表面積 | 15.3 |
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| 水素結合供与体数 | 1 |
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| 水素結合受容体数 | 2 |
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| 回転可能結合数 | 1 |
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| 重原子数 | 9 |
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| 形式電荷 | 0 |
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| 複雑度 | 93.1 |
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| 沸点 | 43°C/7mm |
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| 密度 | 0.94 |
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| 屈折率 | 1.4804 |
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| 貯蔵条件 | Keep in dark place,Sealed in dry,Room Temperature |
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| 外観・状態 | clear liquid |
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| pKa（酸解離定数） | 9.23±0.10(Predicted) |
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| 色 | Colorless to Light yellow |
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| InChI | InChI=1S/C7H14N2/c1-2-7(1)9-5-3-8-4-6-9/h7-8H,1-6H2 |
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| InChIKey | HNZJIWIXRPBFAN-UHFFFAOYSA-N |
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| SMILES | N1(C2CC2)CCNCC1 |
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安全性と法規制
| GHS 分類 | DangerH302 (60%): Harmful if swallowed [Warning Acute toxicity, oral]P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 5 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
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| Hazard Classes and Categories | Acute Tox. 4 (60%) |
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| 輸送番号（UN） | 3267 |
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| 税関コード | 2933599590 |
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| 消防法 | 危-4-3-III |
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| 危険表示 | Xi |
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| 危険等級 | 8 |
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| 包装等級 | Ⅲ |
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用途
使用
1-cyclopropylpiperazine is a piperazine derivative known in the literature by synonyms such as N-cyclopropylpiperazine and 4-cyclopropylpiperazine. It has been used in the preparation of some tri- and tetrasubstituted ureas with histamine H3 antagonist receptor activity, 3-amido-4- anilinoquinolines series as CSF-1R kinase inhibitors, for the synthesis of cyclopropyl amines as modulators of the histamine H3 receptor, sulfonamide compounds as cysteine protease inhibitors, N-oxides as antibacterial agents and in the treatment of the disease caused by helicobacter infection[1].
