Zantac

HCID 47909CAS 66357-59-3

部分構造検索類似構造を探す

基本情報

標準SMILES: CNC(=C[N+](=O)[O-])NCCSCc1ccc(CN(C)C)o1.Cl
InChIKey: GGWBHVILAJZWKJ-UHFFFAOYSA-N
分子式: C13H23ClN4O3S
平均分子量: 350.87 g/mol
単同位体質量: 350.11793928

概要

See also: Ranitidine Hydrochloride (annotation moved to).

名称と識別子

優先名称: Zantac
IUPAC: 1-N'-[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine;hydrochloride

名称と別名

ZANTACRefChem:934486SantanolTanidinaToriolRadin71130-06-8RaniberlranicDigestosanServiradineAlvidina

名称をさらに表示

ArtomilAzuranitMideranNoktomeQuadrinRanibertaRanicuxRanidil

データベース識別子

CAS: 66357-59-3、71130-06-8
PubChem CID: 47909
DTXSID: DTXSID201015892
UNII: BK76465IHM
EC Number: 275-207-4

物性

構造計算による物性

極性表面積: 112 Å²
水素結合供与体数: 3
水素結合受容体数: 7
回転可能結合数: 9
重原子数: 22
形式電荷: 0
複雑度: 347

安全と法規制

GHS分類

GHS Classification · 4 件

Danger

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P233, P260, P261, P264, P264+P265, P271, P272, P280, P284, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 54 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Hazard Classes and CategoriesSkin Irrit. 2 (100%)

化学と産業

薬理情報

MeSH Pharmacological Classification · 2 件

Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.

Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.