基本情報
- CAS
28614-26-8- 標準SMILES
CN1CCN(c2ccc3ccccc3n2)CC1- InChIKey
HOMWNUXPSJQSSU-UHFFFAOYSA-N- 分子式
- C14H17N3
- 平均分子量
- 227.3 g/mol
- 単同位体質量
- 227.14224756
概要
N-methylquipazine is an aminoquinoline that consists of quinoline in which the hydrogen at position 2 is substituted by a 4-methylpiperazin-1-yl group. A 5-HT3 agonist. Has almost the same affinity for 5-HT3 sites as quipazine but unlike the latter, does not bind to 5-HT1B sites. It has a role as a serotonergic agonist. It is an aminoquinoline, a N-alkylpiperazine and a N-arylpiperazine.
名称と識別子
- 優先名称
- N-Methylquipazine
- IUPAC
- 2-(4-methylpiperazin-1-yl)quinoline
- 英語名
- N-Methylquipazine dimaleate
- 分子式
- C14H17N3
- 分子量
- 227.3
名称と別名
N-methylquipazine2-(4-methylpiperazin-1-yl)quinoline28614-26-8quinoline, 2-(4-methyl-1-piperazinyl)-0YV1ZIR6S0J366.838J1-(2-Quinolyl)-4-methylpiperazine2-(1-(4-methyl)-piperazinyl)quinolineDTXSID8043731CHEBI:64164RefChem:927276DTXCID6023731
名称をさらに表示
N-Methylquipazine dimaleateQUIPAZINE, N-METHYL- DIMALEATEN Methylquipazine,NMethylquipazineN-Methylquipazine dimaleate salt2-(1-N-METHYLPIPERAZINYL)QUINOLINE DIMALEATE2-[1-(4-METHYL)-PIPERAZINYL]QUINOLINE DIMALEATE2-[1-(4-Methyl)piperazinyl]quinoline dimaleate salt
CHEMBL2885912-(4-Methyl-piperazin-1-yl)-quinolineTocris-0566Lopac-Q-107Biomol-NT_000084UNII-0YV1ZIR6S0Lopac0_001000Oprea1_654246
データベース識別子
- CAS
28614-26-8- PubChem CID
- 5013
- DTXSID
DTXSID8043731
物性
構造計算による物性
- XLogP
- 2
- 極性表面積
- 19.4 Ų
- 水素結合供与体数
- 0
- 水素結合受容体数
- 3
- 回転可能結合数
- 1
- 重原子数
- 17
- 形式電荷
- 0
- 複雑度
- 248
物理化学的性質
- 貯蔵温度
- 2 · 2-8°C
- 溶解性
- 0.1 M · 0.1 M HCl: 可溶
- 色
- 白い
化学と産業
応用分野
使用N-Methylquipazine dimaleate is a SR-3 agonist.
サプライヤー8 社
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
VDM Biochemicals0330-2528181 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
EMMX Biotechnology LLC888-539-0666 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
珠海奥博凯生物医药技术有限公司400-0628126 · [email protected]
補足説明
定義ChEBI: A maleate salt obtained by reaction of N-methylquipazine with two equivalents of maleic acid. A 5-HT3 agonist. Has almost the same affinity for 5-HT3 sites as quipazine but unlike the latter, doe not bind to 5-HT1B sites.
関連反応
0 件
現在のフィルター条件では反応記録がありません。
化合物ノート
読み込み中…