Lauramidopropyl Dimethylamine (HCID 51392)

概要

The CIR Expert Panel concluded that the 24 fatty acid amidopropyl dimethylamines ingredients listed below are safe in cosmetics when they are formulated to be non-sensitizing, which may be based on a QRA...Lauramidopropyl Dimethylamine...

名称と識別子

優先名称: Lauramidopropyl Dimethylamine
IUPAC: N-[3-(dimethylamino)propyl]dodecanamide
現地名: ジメチル[3-(ドデカノイルアミノ)プロピル]アミン
英語名: N-[3-(DIMETHYLAMINO)PROPYL]LAURAMIDE
分子式: C17H36N2O
分子量: 284.48

名称と別名

N-[3-(dimethylamino)propyl]dodecanamideLauramidopropyl dimethylamineN-[3-(Dimethylamino)propyl]lauramideN-(3-(Dimethylamino)propyl)dodecanamideSCHERCODINE LDodecanamide, N-[3-(dimethylamino)propyl]-(LAURYLAMIDOPROPYL)DIMETHYLAMINEDTXSID8044913FS588RR72JDodecanamide, N-(3-(dimethylamino)propyl)-NSC-79892ZOHAR AMIDO AMINE L

名称をさらに表示

N-[3-(ジメチルアミノ)プロピル]ドデカンアミドジメチル[3-(ドデカノイルアミノ)プロピル]アミンN-ドデカノイル-3-(ジメチルアミノ)-1-プロパンアミンN-ラウロイルアミド-3-N′,N′-ジメチルプロピルアミンLexamine L 13PKO12Einecs 221-661-3Dimethylaminopropyl lauramideLaurylamidopropylDimethylAmineN,N-DimethyllauramidopropylamineLauric 3-dimethylaminopropylamideDodecanoylamidopropyldimethylamineLauroyl(dimethyl amino propyl)amine

3-dodecanamidopropyldimethylamineDTXCID6024913DIMETHYLAMINOPROPYLLAURYLAMIDEN-(3-(Dimethylamino)propyl)lauramide1147459-12-8N,N-DIMETHYLAMINOPROPYLDODECYLAMIDEAmides, C12-18, N-(3-(dimethylamino)propyl)Amides, C12-18, N-[3-(dimethylamino)propyl]

データベース識別子

CAS: 1147459-12-8、3179-80-4
PubChem CID: 51392
DTXSID: DTXSID8044913
ChEMBL: CHEMBL3185963
UNII: FS588RR72J
EC Number: 221-661-3、689-272-5
Nikkaji: J27.687A

物性

構造計算による物性

XLogP: 5.1
極性表面積: 32.3 Å²
水素結合供与体数: 1
水素結合受容体数: 2
回転可能結合数: 14
重原子数: 20
形式電荷: 0
複雑度: 217

実験および物理化学的性質

Cosmetics · 3 件

Cosmetic ingredients (Lauramidopropyl Dimethylamine) -> CIR (Cosmetic Ingredient Review)

Personal care product

Antistatic

Physical DescriptionLiquid; Other Solid; CBI

Collision Cross Section181.8 Å² [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID8044913]

物理化学的性質

融点: 34.5 · 34.5-38.5 °C(lit.)
沸点: 171 · 171-194 °C(Press: 2 Torr)
比重(密度): 0.882 · 0.882±0.06 g/cm3(Predicted)
闪点: 230 °F · >230 °F
溶解性: Chloroform (Slightly), Methanol (Slightly)
酸解離定数(Pka): 16.29 · 16.29±0.46(Predicted)
外見: Low-Melting Solid
色: White to Off-White
化粧品成分の機能: 帯電防止
InChI: InChI=1S/C17H36N2O/c1-4-5-6-7-8-9-10-11-12-14-17(20)18-15-13-16-19(2)3/h4-16H2,1-3H3,(H,18,20)
InChIKey: TWMFGCHRALXDAR-UHFFFAOYSA-N
SMILES: C(NCCCN(C)C)(=O)CCCCCCCCCCC
LogP: 4.561 · 4.561 (est)
表面張力: 27.8 mN/m · 27.8mN/m at 1g/L and 20℃
EPAの化学物質情報: 3 · Dodecanamide, N-[3-(dimethylamino)propyl]- (3179-80-4)

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 0.2% (1 of 653) of reports.

Danger

H302 (25.7%): Harmful if swallowed [Warning Acute toxicity, oral]

P260, P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P332+P317, P333+P317, P362+P364, P363, P391, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 653 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

危険有害性情報

Regulatory Information · 4 件

Chemical: Dodecanamide, N-[3-(dimethylamino)propyl]-

Dodecanamide, N-[3-(dimethylamino)propyl]- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Dodecanamide, N-[3-(dimethylamino)propyl]- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 23-02-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/10713

Dodecanamide, N-3-(dimethylamino)propyl-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Other Safety InformationIMAP assessments - Fatty acid amido propyl dimethylamines: Human health tier II assessment

Hazard Classes and Categories · 3 件

Acute Tox. 4 (25.7%)

Acute Tox. 4 (100%)

Skin corrosion - category 1

毒性情報

Toxicity Summary · 2 件

The CIR Expert Panel concluded that the 24 fatty acid amidopropyl dimethylamines ingredients listed below are safe in cosmetics when they are formulated to be non-sensitizing, which may be based on a QRA...Lauramidopropyl Dimethylamine...

Safe for use in cosmetics, with qualifications

安全データ

wgk: 2
tsca: TSCA listed
risk_code: 36/37/38
hazard_code: Xi
safety_code: 26
Hazard Classifications: Eye Irrit. 2Skin Irrit. 2STOT SE 3
ストレージクラス: 11 - Combustible Solids

化学と産業

用途と製造

UsesCIR ingredient: Lauramidopropyl Dimethylamine

U.S. Production2023: 10,000,000 - <25,000,000 lb

Industry UsesIntermediate

Use ClassificationCosmetics -> Antistatic

General Manufacturing Information · 2 件

All Other Basic Organic Chemical Manufacturing

Dodecanamide, N-[3-(dimethylamino)propyl]-: ACTIVE

応用分野

使用N-(3-(Dimethylamino)propyl)dodecanamide is used in the study of surface chemistry and colloids as a new surfactnt for hydrate anti-agglomeration in hydrocarbon flowlines and seabed oil capture.