データを補完しています。しばらくしてからページを更新すると最新の内容を表示できます
27200-12-0O=C1c2c(O)cc(O)cc2OC(c2cc(O)c(O)c(O)c2)C1OKJXSIXMJHKAJOD-UHFFFAOYSA-N27200-12-0、557792-97-9DTXSID001347411CHEBI:28917安全情報は参考情報です。供給元の安全データシート(SDS)、適用法令、専門家による評価に代わるものではありません。
毒性ラットにおける急性毒性試験ではジヒドロミルセチンは毒性が低く、ラットへの経口投与の最大耐量は5.0g/kgに達したと表明した。
説明Dihydromyricetin (DHM), also known as ampelopsin, is a natural flavonoid compound, which is found in large quantities in Asian plant species. One of them – Hovenia dulcis – is known for centuries in traditional Chinese medicine as a cure for alcohol poisoning and hangover (Liang et al. 2014). DHM is sold as a supplement and is commonly marketed as a treatment for hangovers due to its ability to reduce blood alcohol levels and projected hepatoprotective properties.Dihydromyricetin had beneficial effects on health such as antimicrobial, anti-inflammatory,antioxidative, anticancer, lipid and glucose metabolism-regulatory activities,and cell death-mediating without or with minimum adverse effects on normal cells. And most importantly, DHM has been shown to provide significant hepatoprotective effects. Its positive influence on alcohol-induced and other liver diseases was suggested in the study of acute liver failure (Liu et al. 2017).
使用Dihydromyricetin has been used to study its effect on adipogenesis and glucose uptake in differentiated 3T3-L1 pre-adipocytes. It has also been used to study its antitumor activity against liver cancer cells.
現在のフィルター条件では反応記録がありません。
読み込み中…
定義本品は、次の化学式で表される芳香族化合物である。
定義ChEBI: (+)-dihydromyricetin is an optically active form of dihydromyricetin having (2R,3R)-configuration. It has a role as a metabolite, an antioxidant and an antineoplastic agent. It is a secondary alpha-hydroxy ketone and a dihydromyricetin. It is an enantiomer of a (-)-dihydromyricetin.