CAS 10049-21-5 Sodium Phosphate, Monobasic, Monohydrate (HCID 516949)

名称と識別子

優先名称: Sodium Phosphate, Monobasic, Monohydrate
IUPAC: sodium;dihydrogen phosphate;hydrate
現地名: りん酸一ナトリウム一水和物
英語名: Sodium Phosphate Monobasic Monohydrate
分子式: H4NaO5P
分子量: 137.992291

名称と別名

Sodium phosphate monobasic monohydrateSodium dihydrogen phosphate monohydrateMonosodium phosphate monohydrateSodium phosphate monohydratePhosphoric acid, monosodium salt, monohydrateSODIUM PHOSPHATE, MONOBASIC, MONOHYDRATEsodium dihydrogenphosphate monohydrate593YOG76RNDTXSID6073994CHEBI:114249sodium dihydrogen phosphate--water (1/1)MONOBASIC SODIUM PHOSPHATE MONOHYDRATE

名称をさらに表示

りん酸二水素ナトリウム一水和物りん酸一ナトリウム一水和物リン酸ナトリウム一塩基性一水和物 ACS REAGENT,≥98%リン酸ナトリウム一塩基性一水和物 PURISS. P.A.,ACS REAGENT,≥99.0% (T)りん酸二水素ナトリウム一水和物, GRりん酸一ナトリウム一水和物,USPグレードリン酸ナトリウム一塩基性一水和物PHOSPHATE BUFFERPOTASSIUM PHOSPHATE BUFFERPH 7 BUFFERPhosphate bufferedSODIUMPHOSPHATEMONOBASIC,MONOHYDRATE,GRANULAR,USP,BPRIA BUFFERBUFFER FOR BODDilution bottleBUFFER MDB 9.50

MONOBASIC SODIUM PHOSPHATE, MONOHYDRATESODIUM PHOSPHATE MONOBASIC, MONOHYDRATESODIUM PHOSPHATE MONOBASIC (MONOHYDRATE)SODIUM PHOSPHATE, MONOBASIC MONOHYDRATE [MI]SODIUM PHOSPHATE MONOBASIC,MONOHYDRATE [VANDF]SODIUM PHOSPHATE, MONOBASIC, MONOHYDRATE [II]SODIUM PHOSPHATE,MONOBASIC,MONOHYDRATE [VANDF]SODIUM PHOSPHATE MONOBASIC (MONOHYDRATE) [WHO-DD]

データベース識別子

CAS: 10049-21-5
PubChem CID: 516949
DTXSID: DTXSID6073994
ChEBI: CHEBI:114249
UNII: 593YOG76RN
EC Number: 600-102-0

物性

構造計算による物性

極性表面積: 81.6 Å²
水素結合供与体数: 3
水素結合受容体数: 5
回転可能結合数: 0
重原子数: 7
形式電荷: 0
複雑度: 61

実験および物理化学的性質

Physical Description · 2 件

Dry Powder

White odorless solid; Slightly deliquescent; [Merck Index] White hygroscopic crystals; [Sigma-Aldrich MSDS]

物理化学的性質

融点: 100 °C · 100°C -H₂O
沸点: 399 °C · 399 °C
比重(密度): 2 · 2,04 g/cm3
貯蔵温度: 5 °C · Store at +5°C to +30°C.
溶解性: 2 O: · H2O: 1 M、透明、無色
外見: 個体
酸解離定数(Pka): 7.21 · 7.21
色: 白色半透明
臭い (Odor): 無臭
PH: 4.1 · 4.1-4.5 (25℃, 50mg/mL in H2O)
水溶解度: 水に溶けます。エタノール、エーテル、クロロホルムに不溶。
Merck: 14 · 14,8660
InChI: 1S/Na.H3O4P.H2O/c;1-5(2,3)4;/h;(H3,1,2,3,4);1H2/q+1;;/p-1
InChIKey: BBMHARZCALWXSL-UHFFFAOYSA-M
SMILES: [Na+].[H]O[H].OP(O)([O-])=O
LogP: -2.148 · -2.148 (est)
CAS データベース: 10049 · 10049-21-5(CAS DataBase Reference)
EPAの化学物質情報: Monosodium phosphate monohydrate (10049-21-5)
Absorption: 0.01 at · ≤0.01 at 260nm≤0.01 at 280nm

化学的性質 · 1 件

化学的特性Anhydrous salt: white crystalline powder; slightly hygroscopic; forms sodium acid pyrophosphate, Na2H2P2O7 on heating above 225°C and sodium metaphosphate (NaPO3)n at about 350 to 400°C; very soluble in water, aqueous solution acidic. Monohydrate: white orthorhombic crystals or granules; density 2.04 g/cm3 ; loses its water of crystallization at 100°C; very soluble in water, pH of 1% solution 4.5; insoluble in alcohol. Dihydrate: large transparent crystals; orthorhombic bisphenoidal structure; density 1.915 g/cm 3 ; decomposes at 60°C; very soluble in water; insoluble in alcohol.

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 76.9% (40 of 52) of all reports.

Warning

H315 (21.2%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (21.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (21.2%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 52 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 40 of 52 reports by companies.；There are 4 notifications provided by 12 of 52 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory Information · 3 件

Chemical: Phosphoric acid, monosodium salt, monohydrate

Phosphoric acid, monosodium salt, monohydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phosphoric acid, monosodium salt, monohydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Monosodium dihydrogen phosphate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Phosphoric acid, monosodium salt, monohydrate: Human health tier I assessment

Hazards SummaryMay cause irritation; [Sigma-Aldrich MSDS] See Sodium phosphate, monobasic.

Hazard Classes and CategoriesSkin Irrit. 2 (21.2%)；Eye Irrit. 2 (21.2%)；STOT SE 3 (21.2%)

法規制情報

Regulatory Information · 3 件

Chemical: Phosphoric acid, monosodium salt, monohydrate

Phosphoric acid, monosodium salt, monohydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phosphoric acid, monosodium salt, monohydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Monosodium dihydrogen phosphate: Does not have an individual approval but may be used under an appropriate group standard

安全データ

F: 3
wgk: 1
tsca: Yes
rtecs: WA1900000
毒性: LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rabbit > 7940 mg/kg
hs_code: 2835 22 00
risk_code: 36/37/38-36
hazard_code: Xi
safety_code: 26-36/37/39-36-39-24/25
ストレージクラス: 13 - Non Combustible Solids

化学と産業

用途と製造

UsesUsed in baking powders, boiler water, foods (acidulant and sequestrant), and as a veterinary urinary acidifier; [Merck Index]

U.S. Production2023: 41,887 lb；2022: 14,200 lb；2021: 34,041 lb；2020: 59,762 lb

Consumer UsesNot Known or Reasonably Ascertainable

Industry UsesNot Known or Reasonably Ascertainable

Household ProductsInformation on 1 consumer products that contain Sodium phosphate monobasic monohydrate in the following categories is provided:；• Personal Care

General Manufacturing InformationAll Other Chemical Product and Preparation Manufacturing

応用分野 · 3 件

説明Sodium Phosphate Monobasic Monohydrate is a reagent with very high buffering capacity widely used in molecular biology, biochemistry and chromatography. it can be used as a buffer to adjust pH. In medicine, it is sometimes used as a stimulant laxative before certain operations and medical procedures. Sodium Phosphate Monobasic Monohydrate is often used in foods and in water treatment. It is used as sequestrant, emulsifier, mordant in dyeing, reagent and buffer in foods and analytical chemistry. It is applied as a fireproofing agent and for weighting silk in tanning. It is employed in manufacturing of enamels, ceramics, detergents, boiler compounds, in soldering and brazing instead of borax. Monobasic sodium phosphate is used in baking powders, acid cleansers, electroplating, as a dry acidulant, and in treating boiler water.

使用Sodium Phosphate Monobasic Monohydrate is often used in foods and in water treatment. it can be used as a buffer to adjust pH. In medicine, it is sometimes used as a stimulant laxative before certain operations and medical procedures.

一般的な説明Useful in conjuction with sodium phosphate, dibasic (Cat. No. 567550) in the preparation of biological buffers(absorbance: ≤0.01 at 260 nm and 280 nm).

調製方法 · 2 件

製造方法Monobasic sodium phosphate can be prepared by partial neutralization of phosphoric acid with sodium hydroxide in equimolar amounts: H3PO4+ NaOH →NaH2PO4+ H2O It also can be made by treating disodium hydrogen phosphate with phosphoric acid in proper stoichiometric amount: Na2HPO4+ H3PO4→2NaH2PO4

Monobasic sodium phosphate is prepared by adding phosphoric acid to a hot, concentrated solution of disodium phosphate until the liquid ceases to form a precipitate with barium chloride. This solution is then concentrated and the monobasic sodium phosphate is crystallized.