2-ブタノン オキシム
Butanone oxime
基本情報
- CAS
96-29-7- 標準SMILES
CC/C(C)=N\O- InChIKey
WHIVNJATOVLWBW-PLNGDYQASA-N- 分子式
- C4H9NO
- 平均分子量
- 87.12 g/mol
- 単同位体質量
- 87.06841391
概要
Methyl ethyl ketoxime is a clear colorless liquid with a musty odor. (NTP, 1992)
名称と識別子
- 優先名称
- Butanone oxime
- IUPAC
- (NZ)-N-butan-2-ylidenehydroxylamine
- 現地名
- 2-ブタノン オキシム
- 英語名
- 2-Butanone oxime
- 分子式
- C4H9NO
- 分子量
- 87.12
名称と別名
MEK-oximeButanone oximeTroykyd anti-skin BEthyl methyl ketoximeEthyl methyl ketone oximeMethyl ethyl ketone oximeUSAF AM-3Methyl ethyl ketoximeUSAF EK-9062-Butanone, oximeNSC 442NSC-442
名称をさらに表示
2-ブタノン オキシムメチルエチルケトキシムMEK-オキシムエチルメチルケトンオキシムブタン-2-オン=オキシム2-ブタノンオキシムメチルエチルケトンオキシムエチルメチルケトキシムエチル(メチル)ケトンオキシム2-ブトキシムメチルエチルケトオキシムブタン２オン＝オキシムエチルメチルケトオキシムメチルアルキル(C2～4)ケトオキシム2‐ブタノンオキシム2-ブタノン=オキシムN-(ブタン-2-イリデン)ヒドロキシルアミンMEKOExkin 2Methylethylketoxim(2E)-2-Butanone oximeSKINO
96-29-7WLN: QNUY2&1Skino #2butan-2-one (Z)-oximeEthyl-methylketonoxim [Czech]UNII-51YGE935U9CCRIS 1382HSDB 8043
データベース識別子
- CAS
96-29-7- PubChem CID
- 5324276
- UNII
- 51YGE935U9
- EC Number
- 202-496-6
- Nikkaji
- J97.905H
物性
構造計算による物性
- XLogP
- 0.7
- 極性表面積
- 32.6 Ų
- 水素結合供与体数
- 1
- 水素結合受容体数
- 2
- 回転可能結合数
- 1
- 重原子数
- 6
- 形式電荷
- 0
- 複雑度
- 58.6
実験および物理化学的性質
Chemical ClassesNitrogen Compounds -> Oximes
SpringerMaterials PropertiesOptical coefficient
Density
0.9232 at 68 °F (NTP, 1992) - Less dense than water; will float
0.923 @ 20°C
Solubilitygreater than or equal to 100 mg/mL at 72 °F (NTP, 1992)
Flash Point138 °F (NTP, 1992)
Boiling Point
306 °F at 760 mmHg (NTP, 1992)
152 °C @760 [mm Hg]
Melting Point
-21.1 °F (NTP, 1992)
-29.5 °C
Vapor Density3 (NTP, 1992) - Heavier than air; will sink (Relative to Air)
Vapor Pressure
22.6 mmHg at 73 °F ; 50.9 mmHg at 118 °F (NTP, 1992)
0.9 [mmHg]
Physical Description
Methyl ethyl ketoxime is a clear colorless liquid with a musty odor. (NTP, 1992)
CBI; Liquid
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
Danger
H301: Toxic if swallowed [Danger Acute toxicity, oral]
P203, P260, P261, P264, P264+P265, P270, P271, P272, P280, P301+P316, P302+P352, P304+P340, P305+P354+P338, P308+P316, P317, P318, P319, P321, P330, P332+P317, P333+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
This chemical does not meet GHS hazard criteria for < 0.1% (2 of 4723) of reports.
Danger
H312 (> 99.9%): Harmful in contact with skin [Warning Acute toxicity, dermal]
危険有害性情報
Regulatory Information
Chemical: 2-Butanone, oxime
2-Butanone, oxime is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 2-Butanone, oxime are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: Butanone oxime (EC: 202-496-6)
2-Butanone, oxime: HSNO Approval: HSR001191 Approved with controls
Other Safety InformationEvaluation - 2-Butanone, oxime (MEKO)
DOT LabelFlammable Liquid
Fire HazardsThis chemical is combustible. (NTP, 1992)
Health HazardsSYMPTOMS: Symptoms of exposure to this compound may include slight eye and skin irritation. It may interfere with alcohol metabolism resulting in the formation of acetaldehyde, blotchy red marks, red eyes, tiredness and visible veins.
Hazards Summary
A skin sensitizer; [Quick CPC] Dermal sensitization, hemolytic anemia, and CNS depression reported in animal studies; Hemolytic effects were seen in a 4-week inhalation study at 533 ppm, but not at 283 ppm; MEKO has been produced since 1958, and no adverse effects in workers have been reported; Painters using alkyd paints containing MEKO were exposed at levels <1-2 ppm; [AIHA] 8-hour exposure of 12 rats to saturated atmosphere caused no mortalities; Hematological changes (increased methemoglobin and reticulocytes and decreased hemoglobin) observed in 4-week inhalation study of rats at 400 ppm; In a 13-week oral neurotoxicity study of rats, transient neurobehavioral changes were observed immediately following administration, but reversed by the next day; No progressive long term neurotoxicity observed; [IUCLID]
化学と産業
用途と製造
Uses
Used as an anti-skinning agent in alkyd paints; Also used as a blocking agent (urethane polymers) and a corrosion inhibitor (boilers); [AIHA]
Painting (Pigments, Binders, and Biocides) [Category: Paint]
U.S. Production2023: 2,500,000 - <4,000,000 lb
Consumer UsesDeflocculant
Industry UsesDeflocculant
Household ProductsInformation on 222 consumer products that contain Methyl ethyl ketoxime in the following categories is provided:
General Manufacturing Information
Machinery Manufacturing
2-Butanone, oxime: ACTIVE
応用分野
用途塗料の皮張り防止剤、シリコン樹脂の硬化剤およびウレタンのブロッキング剤
用途有機合成原料。
使用2-Butanone oxime was employed as reagent and solvent in the syntheses of ketoimine and 2,4-dipyridyl-1,3,5-triazapentadiene palladium(II) complexes. It was also used in the synthesis of novel acetaldiimine cobalt complex, [CoI2{((CH3CH2)(CH3)C=NO)2C(CH3)2}]. Methyl ethyl ketoxime is used primarily as an antiskinning agent in alkyd coating resins
一般的な説明Clear colorless liquid with a musty odor.
調製方法
製造方法2-Butanone oxime is obtained by the reaction of butanone and hydroxylamine hydrochloride. It can also be synthesized by the reaction between butanone and hydroxylamine sulfate.
合成方法2-ブタノールのCu-Zn触媒による気相脱水素
上流・下流製品情報
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