ニトロフラゾン

解説ニトロフラゾン,黄色の結晶性の粉末で，無臭，わずかに苦味を呈する．ジメチルホルムアミドに可溶，水，エタノール，酢酸エチルに難溶，エーテル，クロロホルムに不溶．局所殺菌消毒薬．各種のグラム陰性および陽性菌に有効である．数日以上続けて使用すると皮膚の過敏症を起こすことがある．皮膚表面の感染症に軟膏または0.2～0.02％ 溶液として局所的に用いる．[CAS 59-87-0]森北出版「化学辞典（第2版）

説明Nitrofurazone is an antibacterial agent used in animal feed. Occupational dermatitis was reported in cattle breeders and farmers.

使用Nitrofurazone is a topical anti-infective and bactericide for most pathogens commonly causing surface infections; in the adjunctive therapy of patients with second and third degree bums when bacterial resistance to other agents is areal or potential problem; in skin grafting where bacterial contamination may cause graft rejection and/or donor-site infection; antibacterial agent for the treatment or prevention of infections in a variety of conditions involving skin, eyes, ears, nose and genito-urinary tract; used on pyodermas, ulcers, and wounds; affects some protozoa and is an effective prophylaxis against nosocomial infections; antiseptic lubricant for trans urethral resection; anti-microbial in veterinary medicine.

一般的な説明Odorless pale yellow needles or yellow powder. pH (saturated aqueous solution) 6.0 - 6.5. Alkaline solutions are dark orange.

定義ChEBI: A semicarbazone resulting from the formal condensation of semicarbazide with 5-nitrofuraldehyde. A broad spectrum antibacterial drug, although with little activity against Pseudomonas species, it is used as a local application for burns, ulcer , wounds and skin infections.