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基本情報
- CAS
99291-20-0- 標準SMILES
CSCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)C1CCCN1C(=O)[C@@H](N)C(C)C)C(C)C)C(C)C)C(=O)O- InChIKey
AIKMAJWJXJPJNB-HNRKYVDVNA-N- 分子式
- C42H69N9O14S
- 平均分子量
- 956.12 g/mol
名称と識別子
- 優先名称
- V-9-M cholecystokinin nonapeptide
- 英語名
- V-9-M cholecystokinin nonapeptide
- 分子式
- C42H69N9O14S
- 分子量
- 956.12
名称と別名
Cholecystokinin Precursor (24-32) (rat) H-Val-Pro-Val-Glu-Ala-Val-Asp-Pro-Met-OHSmeglutideSemaglutide（Recombinant）Cholecystokinin PrecursorV-9-M cholecystokinin nonapeptideL-Valyl-L-prolyl-L-valyl-L-α-glutamyl-L-alanyl-L-valyl-L-α-aspartyl-L-prolyl-L-methionineL-Methionine,L-valyl-L-prolyl-L-valyl-L-a-glutamyl-L-alanyl-L-valyl-L-a-aspartyl-L-prolyl-L-Methionine, L-valyl-L-prolyl-L-valyl-L-α-glutamyl-L-alanyl-L-valyl-L-α-aspartyl-L-prolyl-Cholecystokinin precursor (24-32), also known as semaglutide, is a human yeast fermented substanceV 9 M|||Prepro CCK Fragment V-9-M|||Val-pro-val-glu-ala-val-asp-pro-met|||Cholecystokinin Precursor (24-32)|||V9M|||V-9-M
データベース識別子
- CAS
99291-20-0- PubChem CID
- 5489386
物性
物理化学的性質
- 沸点
- 1350.7 · 1350.7±65.0 °C(Predicted)
- 比重(密度)
- 1.306 · 1.306±0.06 g/cm3(Predicted)
- 酸解離定数(Pka)
- 3.51 · 3.51±0.10(Predicted)
- 外見
- Solid
- 色
- White to off-white
- InChIKey
- AIKMAJWJXJPJNB-HNRKYVDVNA-N
化学と産業
応用分野
説明V-9-M Cholecystokinin nonapeptide is a glucagon-like peptide receptor agonist, namely GLP-1 receptor agonist. Human GLP-1 is a peptide hormone secreted by intestinal L cells. Cholecystokinin Precursor (24-32), rat has apparent sedative actions and prevents experimental amnesisa in rats.
使用V-9-M cholecystokinin nonapeptide belongs to the glucagon-like peptide-1 receptor agonist (GLP-1 receptor agonist) class of hypoglycemic drugs, which increase insulin secretion in a glucose-dependent manner and inhibit glucagon secretion , and can promote gastric emptying, centrally suppress appetite, reduce food intake, and then reduce glucose absorption to achieve the effect of lowering blood sugar.
一般的な説明V-9-M cholecystokinin nonapeptide, also known as Cholecystokinin Precursor (24-32) (rat), is a precursor compound of cholecystokinin (CCK) that is expressed in the heart, lungs, and kidneys as well as in the gastrointestinal tract and brain. Cholecystokinin (CCK) is a brain-gut peptide that stimulates gallbladder contraction and pancreatic exocrine secretion, as well as a neurotransmitter. It can be extracted from the small intestine of dogs and cats and causes gallbladder contractions.
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