Navuridine

HCID 55262CAS 84472-85-5

基本情報

標準SMILES: [N-]=[N+]=N[C@H]1C[C@H](n2ccc(=O)[nH]c2=O)O[C@@H]1CO
InChIKey: ZSNNBSPEFVIUDS-SHYZEUOFSA-N
分子式: C9H11N5O4
平均分子量: 253.22 g/mol
単同位体質量: 253.08110383

概要

Navuridine is a dideoxyuridine inhibitor of HIV reverse transcriptase that is related to zidovudine. Navuridine exhibits a relatively short half-life and incomplete oral bioavailability and has not been developed into a clinical drug.

名称と識別子

優先名称: Navuridine
IUPAC: 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

名称と別名

Navuridine84472-85-5AZdU3'-AZIDO-2',3'-DIDEOXYURIDINEAZddUCS-87NavuridinaUridine, 3'-azido-2',3'-dideoxy-NSC-380882PS28W654793'-azido-2',3'dideoxyuridinenavuridinum

名称をさらに表示

NSC380882RefChem:9275253'-azido-2'-3'-dideoxyuridineNavuridine [INN]1-((2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dioneMFCD008703241-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dioneAzUrd