N-(4-(4-アミノピペリジン-1-イル)-2-メトキシフェニル)-5-クロロ-4-(1H-インドール-3-イル)ピリミジン-2-アミン

AZD3463 is a member of the class of indoles that is 1H-indole substituted by a 2-[4-(4-aminopiperidin-1-yl)-2-methoxyanilino]-5-chloropyrimidin-4-yl group at position 3. It is an orally bioavailable dual inhibitor of ALK and IGF1R with Ki value of 0.75 nM for ALK. It has a role as an autophagy inducer, an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an apoptosis inducer. It is a member of indoles, a monomethoxybenzene, an organochlorine compound, an aminopyrimidine, an aminopiperidine, a secondary amino compound and a tertiary amino compound.