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13609-67-1CCCC(=O)O[C@]1(C(=O)CO)CCC2[C@@H]3CCC4=CC(=O)CC[C@]4(C)C3[C@@H](O)C[C@@]21C13609-67-1CHEMBL3039247安全情報は参考情報です。供給元の安全データシート(SDS)、適用法令、専門家による評価に代わるものではありません。
説明Hydrocortisone 17-butyrate: a new non-fluorinated topical corticosteroid.Hydrocortisone 17-butyrate could be used in psoriasis, eczema and other inflammatory dermatoses. It may be found in creams, lotions, ointments, and powders and in ear, nose and eye drops for rhinitis, otitis, and conjunctivitis. In double-blind paired comparisons with other topical corticosteroids, the efficacy of hydrocortisone 17-butyrate 0.1% has generally been indistinguishable from that of triamcinolone acetonide 0.1%, fluocinolone acetonide 0.025% or betamethasone 17-valerate 0.1% in patients with eczema or psoriasis. When applied to the face of patients with atrophy superimposed on rosacea and perioral dermatitis resulting from prolonged use of fluorinated topical corticosteroids, hydrocortisone 17-butyrate 0.1% did not prevent the beneficial effect of systemic tetracycline nor the disappearance of telangiectasis and tended to be more effective than hydrocortisone 1%[1].
使用Hydrocortisone-17-butyrate is a topical corticosteroid with anti-inflammatory properties; marker for topical corticosteroid allergy.
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定義ChEBI: Cortisol esterified with butyric acid at the 17-hydroxy group.