基本情報
- CAS
9008-97-3- 標準SMILES
COc1cc(OC)c2c(c1)OC(c1ccc(OC)c(OC)c1)CC2O- InChIKey
APLKIOPSKVXHFK-UHFFFAOYSA-N- 分子式
- C19H22O6
- 平均分子量
- 346.4 g/mol
- 単同位体質量
- 346.14163842
概要
Mucoproteins isolated from the kidney bean (Phaseolus vulgaris); some of them are mitogenic to lymphocytes, others agglutinate all or certain types of erythrocytes or lymphocytes. They are used mainly in the study of immune mechanisms and in cell culture.
名称と識別子
- 優先名称
- Phytohemagglutinins
- IUPAC
- 2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-3,4-dihydro-2H-chromen-4-ol
- 現地名
- ファセオルスブルガリス凝集素
- 英語名
- PHYTOHEMAGGLUTININ PHA-M
- 分子量
- 0
名称と別名
Phytohemagglutinins9008-97-3Plant HemagglutininsHemagglutinins, PlantRefChem:389217Lectin2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-3,4-dihydro-2H-chromen-4-olLectin from Phaseolus vulgaris (red kidney bean)2-(3,4-Dimethoxyphenyl)-3,4-dihydro-5,7-dimethoxy-2H-1-benzopyran-4-ol2H-1-Benzopyran-4-ol, 2-(3,4-dimethoxyphenyl)-3,4-dihydro-5,7-dimethoxy-2-(3,4-Dimethoxyphenyl)-5,7-dimethoxy-4-chromanol #10496-69-2
名称をさらに表示
ファセオルスブルガリス凝集素フィトヘマグルチニン-Pフィトヘマグルチニンp-(ヘキシルアミノ)フェノール4-(ヘキシルアミノ)フェノールPHA-LPHA-PPHASEOLUS VULGARIS LEUCOAGGLUTININPHA-CPHA-MDog PHAPHA-P PHA-LPhytolectinPHA proteinfitohemaglutynina
物性
構造計算による物性
- XLogP
- 2.6
- 極性表面積
- 66.4 Ų
- 水素結合供与体数
- 1
- 水素結合受容体数
- 6
- 回転可能結合数
- 5
- 重原子数
- 25
- 形式電荷
- 0
- 複雑度
- 419
実験および物理化学的性質
Chemical ClassesBiological Agents -> Plant Toxins
Physical DescriptionPowder; [Sigma-Aldrich MSDS]
物理化学的性質
- 貯蔵温度
- 2 · Sealed in dry,2-8°C
- 溶解性
- 2 mg/mL · PBS: 2 mg/mL
- 外見
- 無塩凍結乾燥粉末
- 色
- White to light yellow
- 由来生物
- Phaseolus vulgaris
- 化粧品成分の機能
- スキンコンディショニング - その他
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
危険有害性情報
Regulatory InformationAgglutinins and Lectins, phytohemagglutinins: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryMay cause irritation; [Sigma-Aldrich MSDS]
安全データ
- F
- 10-21
- wgk
- WGK 3
- rtecs
- TJ3470000
- safety_code
- 22-24/25
- ストレージクラス
- 11 - Combustible Solids
化学と産業
薬理情報
MeSH Pharmacological Classification
A substance that makes particles (such as bacteria or cells) stick together to form a clump or a mass.
Agents that cause agglutination of red blood cells. They include antibodies, blood group antigens, lectins, autoimmune factors, bacterial, viral, or parasitic blood agglutinins, etc.
Substances that stimulate mitosis and lymphocyte transformation. They include not only substances associated with LECTINS, but also substances from streptococci (associated with streptolysin S) and from strains of alpha-toxin-producing staphylococci. (Stedman, 25th ed)
応用分野
用途細胞表面糖鎖の検索等。
使用Phytohemagglutinin-M (PHA-M) has been used in the activation of Jurkat and primary cells. It has also been used to treat polymorphonuclear blood cells(PMBCs)
一般的な説明Lectins are distinct proteins or glycoproteins that have at least one non-catalytic domain which fixes reversibly to a definite mono- or oligosaccharide. Some of their potentially utilizable biological assets include: antitumor, immunomodulatory and anti-insect, antifungal, antibacterial, anti-HIV, and mitogenic properties.
サプライヤー100 社
北京华美互利生物化工010-56205725 · [email protected]
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖南韵邦生物科技股份有限公司0731-88532326 13319508186 · [email protected]
南通飞宇生物科技有限公司0513-68819626 15152877458 · [email protected]
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