α-エチル-2-オキソ-1-ピロリジンアセトアミド

alpha-ethyl-2-oxo-1-Pyrrolidineacetamide

HCID 59708CAS 33996-58-6

部分構造検索類似構造を探す

基本情報

標準SMILES: CCC(C(N)=O)N1CCCC1=O
InChIKey: HPHUVLMMVZITSG-UHFFFAOYSA-N
分子式: C8H14N2O2
平均分子量: 170.21 g/mol
単同位体質量: 170.10552769

名称と識別子

優先名称: alpha-ethyl-2-oxo-1-Pyrrolidineacetamide
IUPAC: 2-(2-oxopyrrolidin-1-yl)butanamide
現地名: α-エチル-2-オキソ-1-ピロリジンアセトアミド
英語名: Etiracetam
分子式: C8H14N2O2
分子量: 170.21

名称と別名

Etiracetam33996-58-62-(2-oxopyrrolidin-1-yl)butanamidealpha-Ethyl-2-oxo-1-pyrrolidineacetamideEtiracetamumUCB-6474DTXSID5046510230447L0GL1-Pyrrolidineacetamide, alpha-ethyl-2-oxo-DTXCID3026510RefChem:139255UCB 6474

名称をさらに表示

エチラセタムα-エチル-2-オキソ-1-ピロリジンアセトアミドレベチエチラセタムIC MIXTURE (1:1 MIXTURE OF LEVETIRACETAM S-ENANTIOMER-(2S)-2-(2-OXOPYRROLIDIN-1-YL)BUTANAMIDE AND LEVETIRACETAM R-ENANTIOMER (2R)-2-(2-OXOPYRROLIDIN-1-YL)BUTANAMIレベチエチラセタムic Mixture (1:1 mixture of levetiracetam S-enantiomer-(2S)-2-(2-oxopyrrolidin-1-yl)butanamide and levetiracetam R-enantiomer (2R)-2-(2-oxopyrrolidin-1-yl)butanamide)2-(2-オキソピロリジン-1-イル)ブタンアミドrac-LevetiracetamEtiracetam USP/EP/BPSALOR-INT L127760-1EA(+-)-1-pyrrolidineacetamidLevetiracetam Impurity CRSLevetiracetaM RaceMic Mixturerac-Levetiracetam / Etiracetam

Etiracetam [INN]Levetiracetam-d3(R)-LevetiracetamMFCD00868507NCGC00165970-01Etiracetamum [INN-Latin]CAS-33996-58-6Levetiracetam Racemate

データベース識別子

CAS: 33996-58-6
PubChem CID: 59708
DTXSID: DTXSID5046510
ChEMBL: CHEMBL1400561
ChEBI: CHEBI:176724
UNII: 230447L0GL
EC Number: 642-997-0
Nikkaji: J17.546C

物性

構造計算による物性

XLogP: -0.3
極性表面積: 63.4 Å²
水素結合供与体数: 1
水素結合受容体数: 2
回転可能結合数: 3
重原子数: 12
形式電荷: 0
複雑度: 203

物理化学的性質

融点: 113 · 113-114 °C(Solv: acetone (67-64-1))
沸点: 395.9 · 395.9±25.0 °C(Predicted)
比重(密度): 1.168 · 1.168±0.06 g/cm3(Predicted)
蒸気圧: 0 Pa · 0Pa at 25℃
貯蔵温度: -20 °C · Store at -20°C
溶解性: Chloroform (Slightly), Methanol (Slightly)
酸解離定数(Pka): 15.74 · 15.74±0.50(Predicted)
外見: Solid
色: White to off-white
水溶解度: 401 g/L · 401g/L at 20℃
BRN: 1529106 · 1529106
LogP: 0.7 at · 0.7 at 20℃

化学的性質

化学的特性White Solid

安全と法規制

安全データ

ridadr: UN 3077 9 / PGIII
毒性: mouse,LD50,intravenous,1790mg/kg (1790mg/kg),United States Patent Document. Vol. #4696943,
hs_code: 2933790002
risk_code: 22-36-51/53
hazard_code: Xn,N
safety_code: 26-61

化学と産業

応用分野

使用A nootropic drug that produced a significant increase in β-wave activity and stimulated α-wave activity dose-dependently. Etiracetam has been used in studies to alleviate the effects of memory retrieval defic its in rats.