化工社化工社 化学情報印刷レポート · 研究参考用
HCID 6019作成日：2026年10月27日
Pyridoxine Hydrochloride
PYRIDOXOL · PYRIDOXIN · 4,5-BIS-HYDROXYMETHYL-2-METHYL-PYRIDIN-3-OL · 4,5-BIS(HYDROXYMETHYL)-2-METHYL-3-PYRIDINOL
https://huagongshe.com/ja/chemical/6019
識別子と物理属性
| CAS No. | 12001-77-3 |
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| 分子式 | C8H11NO3.ClH |
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| 平均分子量 | 205.64 g/mol |
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| 単同位体質量 | 205.05057092 g/mol |
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| SMILES | Cc1ncc(CO)c(CO)c1O.Cl |
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| InChIKey | ZUFQODAHGAHPFQ-UHFFFAOYSA-N |
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| PubChem CID | 6019 |
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| ChEMBL | CHEMBL1200756 |
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| ChEBI | CHEBI:30961 |
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| EC No. | 200-386-2 |
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| DTXSID | DTXSID1040792 |
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化学・物理的性質
| 極性表面積 | 73.6 |
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| 水素結合供与体数 | 4 |
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| 水素結合受容体数 | 4 |
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| 回転可能結合数 | 2 |
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| 重原子数 | 13 |
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| 形式電荷 | 0 |
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| 複雑度 | 142 |
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| 物質分類 | Biological Agents -> Vitamins and Derivatives |
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| 化粧品 | Hair conditioningSkin conditioningAntistatic |
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| pH | pH of 10% "wt in vol" soln in water: 3.2 |
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| 味 | BITTER TASTE |
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| 食品添加物 | NUTRIENT SUPPLEMENT -> FDA Substance added to food |
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| Color/Form | Platelets or thick, birefringent rods from alcohol + acetonePLATES FROM ALCOHOL, ACETONECOLORLESS OR WHITE CRYSTALS OR WHITE CRYSTALLINE POWDERWhite to practically white crystals or crystalline powder.Colorless-white platelets |
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| 溶解度 | 5 to 10 mg/mL at 68 °F (NTP, 1992)1 g dissolves in about 4.5 ml water, 90 ml alcoholsol in propylene glycolsparingly sol in acetoneinsol in ether, chloroformSoluble in alc, acetoneslightly soluble in other organic solvents.In water, 2.2X10+5 mg/l, temp not specified. |
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| Human Drugs | Breast FeedingLactationMilk, HumanVitaminsFDA approved drugs -> Active ingredient |
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| 沸点 | Sublimes |
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| Decomposition | When heated to decomposition it emits very toxic fumes of oxides of nitrogen and hydrogen chloride. |
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| 融点 | 207 °C159-162 °C(lit.) |
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| 蒸気圧 | 0.00000006 [mmHg] |
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| 化粧品成分の機能 | スキンコンディショニングヘアコンディショニング帯電防止 |
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安全性と法規制
| GHS 分類 | This chemical does not meet GHS hazard criteria for 7.1% (22 of 309) of reports.DangerH318 (88.3%): Causes serious eye damage [Danger Serious eye damage/eye irritation]P264+P265, P280, P305+P354+P338, and P317 (click each P-code to see the statement)Aggregated GHS information provided per 309 reports by companies from 16 notifications to the ECHA C&L Inventory. |
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| 規制情報 | Chemical: 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochlorideRegulation (EC) No 1831/2003 (amended)Status: Active Update: 16-07-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/17066Pyridoxine hydrochloride: Non hazardous |
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| 火災危険 | Flash point data for this chemical are not available. It is probably combustible. (NTP, 1992) |
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| 健康有害性 | SYMPTOMS: Symptoms of exposure to this compound may include drowsinesslethargyfatiguedisorientationdizzinessunsteady gaittinnitusheadacheblurred visionnervousnesstremorsirritabilityepigastric painnauseavomitingdiarrhea and/or constipationdry mouthpalpitationshallucinationshypnosiscoma and seizures. (NTP, 1992) |
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| 有害性の概要 | Causes convulsions, excitement, other liver changes, and multiple enzyme effects in acute oral studies of rats[RTECS] Excessive, chronic ingestion (2-5 g/d for several months) can cause peripheral neuropathy[Olson, p. 446] May cause irritation[Sigma-Aldrich MSDS] |
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| FDA 要件 | Manufacturers, packers, and distributors of drug and drug products for human use are responsible for complying with the labeling, certification, and usage requirements as prescribed by the Federal Food, Drug, and Cosmetic Act, as amended (secs 201-902, 52 Stat. 1040 et seq., as amended |
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